[125I]2-(2-chloro-4-iodo-phenylamino)-5-methyl-pyrroline (LNP 911), a high-affinity radioligand selective for I1 imidazoline receptors

Molecular Pharmacology

Volumn 62, Issue 1, 2002, Pages 181-191

  Greney, Hugues ^a   Urosevic, Dragan ^a   Schann, Stephan ^a   Dupuy, Laurence ^a   Bruban, Véronique ^a   Ehrhardt, Jean Daniel ^a   Bousquet, Pascal ^a   Dontenwill, Monique ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 CHLORO 4 IODOPHENYLAMINO) 5 METHYLPYRROLINE I 125; 4 CHLORO 2 (2 IMIDAZOLIN 2 YLAMINO)ISOINDOLINE; ALPHA 2 ADRENERGIC RECEPTOR; EFAROXAN; IMIDAZOLINE RECEPTOR; LNP 911; METIZOLINE; MOXONIDINE; RADIOLIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; 2 (2 CHLORO 4 IODOPHENYLAMINO) 5 METHYLPYRROLINE; 2-(2-CHLORO-4-IODOPHENYLAMINO)-5-METHYLPYRROLINE; DRUG RECEPTOR; IMIDAZOLE DERIVATIVE; IMIDAZOLINE I1 RECEPTORS; PYRROLIDINE DERIVATIVE; RADIOACTIVE IODINE; RECEPTOR, ADRENERGIC, ALPHA 2A; RECEPTOR, ADRENERGIC, ALPHA-2A;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISSOCIATION; DOSE RESPONSE; DRUG STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RECEPTOR AFFINITY; RECEPTOR BINDING; SIGNAL TRANSDUCTION; ANIMAL; CELL MEMBRANE; CELL STRAIN; DRUG EFFECT; DRUG INTERACTION; METABOLISM; RADIOASSAY; RAT;

ALLOSTERIC REGULATION; ANIMALS; BINDING SITES; CELL MEMBRANE; DRUG INTERACTIONS; IMIDAZOLES; IODINE RADIOISOTOPES; PC12 CELLS; PYRROLIDINES; RADIOLIGAND ASSAY; RATS; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, DRUG; SIGNAL TRANSDUCTION;

EID: 0035983543     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.1.181     Document Type: Article

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