GM-CSF and M-CSF modulate β-chemokine and HIV-1 expression in microglia

GLIA

Volumn 39, Issue 2, 2002, Pages 174-183

  Si, Qiusheng ^a   Cosenza, Melissa ^a   Zhao, Meng Liang ^a   Goldstein, Harris ^a   Lee, Sunhee C ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

chemokine; GM CSF; HIV 1; M CSF; Microglia

Indexed keywords

BETA CHEMOKINE; COLONY STIMULATING FACTOR 1; GAG PROTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYBRID PROTEIN; IMMUNOLOGICAL ADJUVANT; MACROPHAGE INFLAMMATORY PROTEIN 1; RANTES;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; BRAIN; CELL CULTURE; CELL DIVISION; DOSE RESPONSE; DRUG EFFECT; FEMALE; FETUS; GENETICS; HEAT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; MICROGLIA; PATHOLOGY; PREGNANCY; VIROLOGY; VIRUS REPLICATION;

ADJUVANTS, IMMUNOLOGIC; AIDS DEMENTIA COMPLEX; BRAIN; CELL DIVISION; CELLS, CULTURED; CHEMOKINES, CC; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEAT; HIV CORE PROTEIN P24; HIV-1; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGE INFLAMMATORY PROTEIN-1; MICROGLIA; PREGNANCY; RANTES; RECOMBINANT FUSION PROTEINS; VIRUS REPLICATION;

EID: 0035983278     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.10095     Document Type: Article

References (55)

1. Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates
2. The inhibitory effect of RANTES on the infection of primary macrophages by R5 human immunodeficiency virus type-1 depends on the macrophage activation state
3. Phase III study of granulocyte-macrophage colony-stimulating factor in advanced HIV disease: Effect on infections, CD4 cell counts and HIV suppression
4. RANTES: A versatile and controversial chemokine
5. Aggregation of RANTES is responsible for its inflammatory properties: Characterization of nonaggregating, noninflammatory RANTES mutants
6. AIDS dementia complex and HIV-1 brain infection: Clinical-virological correlations
7. A randomized, placebo-controlled trial of granulocyte-macrophage colony-stimulating factor and nucleoside analogue therapy in AIDS
8. Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton
9. A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
10. Multiple cis regulatory elements control RANTES promoter activity in alveolar epithelial cells infected with respiratory syncytial virus
11. + T cells
12. GM-CSF and its effects on replication of HIV-1 in cells of macrophage lineage
13. Identification of a major co-receptor for primary isolates of HIV-1
14. Granulocyte-macrophage colony-stimulating factor: Potential therapeutic, immunological and antiretroviral effects in HIV infection
15. Chemokine receptor regulation and HIV type 1 tropism in monocyte-macrophages
16. Soluble CD40 ligand induces β-chemokine production by macrophages and resistance to HIV-1 entry
17. + cells is mediated by the chemokine receptor CC-CKR-5
18. Brain dendritic cells and macrophages/microglia in central nervous system inflammation
19. Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor treated monocytes
20. Regulation of RANTES chemokine gene expression requires cooperation between NF-κB and IFN-regulatory factor transcription factors
21. Role of the β-chemokine receptor CCR3 and CCR5 in human immunodeficiency virus type I infection of monocytes and microglia
22. Colony-stimulating factors are promoters of ameboid microglia
23. Immunocytochemical quantification of human immunodeficiency virus in the brain: Correlations with dementia
24. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia
25. The vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in non-dividing host cells
26. Granulocyte-macrophage colony-stimulating factor inhibits HIV-1 replication in monocyte-derived macrophages
27. Role of MIP-1β and RANTES in HIV-1 infection of microglia: Inhibition of infection and induction by IFNβ
28. The effects of human immunodeficiency virus in the central nervous system
29. Phenotype of HIV-1 lacking a functional nuclear localization signal in matrix protein of gag and Vpr is comparable to wild-type HIV-1 in primary macrophages
30. Macrophage colony-stimulating factor antagonists inhibit replication of HIV-1 in human macrophages
31. Characterization of human fetal dissociated CNS cultures with an emphasis on microglia
32. Productive infection of human fetal microglia by HIV-1
33. Cytokine production by human fetal microglia and astrocytes: Differential induction by LPS and IL-1β
34. Macrophage colony stimulating factor (CSF-1) in astrocytes and microglia: Differential regulation by cytokines and LPS and inhibition of class II MHC expression on microglia
35. GM-CSF promotes proliferation of human fetal and adult microglia in primary cultures
36. Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression
37. Expression of type II nitric oxide synthase in primary human astrocytes and microglia: Role of IL-1β and IL-1 receptor antagonist
38. Chemokines - Chemotactic cytokines in inflammation
39. Production of hematopoietic colony-stimulating factors by astrocytes
40. The AIDS dementia complex. II. Neuropathology
41. The AIDS dementia complex. I. Clinical features
42. Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a pathway dependent on nuclear factor-kappaB
43. Integration of murine leukemia virus DNA depends on mitosis
44. Chemokines
45. +, T-cell clones correlates with the clinical state of HIV-1-infected individuals and may be responsible for blocking infection with non-syncytium-inducing HIV-1 in vitro
46. Developmental plasticity of CNS microglia
47. Hematopoietic growth factors signal through the formation of reactive oxygen species
48. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
49. Productive HIV-1 infection of macrophages restricted to the cell fraction with proliferative capacity
50. Signals for activation of the GM-CSF promoter and enhancer in T cells
51. HIV nuclear import: What's the flap?
52. Cytokine regulation of human immunodeficiency virus type 1 entry and replication in human monocytes/macrophages through modulation of CCR5 expression
53. Specific tropism of HIV-1 for microglial cells in primary human brain cultures
54. Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome
55. Expression of iNOS, IL-1 and caspase-1 in HIV-1 encephalitis