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Volumn 253, Issue 2, 1999, Pages 170-180

Phenotype of HIV-1 lacking a functional nuclear localization signal in matrix protein of gag and Vpr is comparable to wild-type HIV-1 in primary macrophages

Author keywords

HIV 1; Macrophages; Matrix NLS; Vpr

Indexed keywords

APHIDICOLIN; GAG PROTEIN; MATRIX PROTEIN; RNA DIRECTED DNA POLYMERASE; VPR PROTEIN;

EID: 0033585371     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1998.9482     Document Type: Article
Times cited : (48)

References (42)
  • 1
    • 0030777412 scopus 로고    scopus 로고
    • Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways
    • Blauvelt, A., Asada, H., Saville, M. W., Klaus-Kovtun, V., Altman, D. J., Yarchoan, R., and Katz, S. I. (1997). Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways. J. Clin. Invest 100, 2043-2053.
    • (1997) J. Clin. Invest , vol.100 , pp. 2043-2053
    • Blauvelt, A.1    Asada, H.2    Saville, M.W.3    Klaus-Kovtun, V.4    Altman, D.J.5    Yarchoan, R.6    Katz, S.I.7
  • 3
    • 0025875699 scopus 로고
    • Enhanced detection of HIV-1 sequences using PCR and a liquid hybridization technique
    • Bruisten, S. M., Koppelman, M. H. G. M., Van der Poel, C. L., and Huisman, J. G. (1991). Enhanced detection of HIV-1 sequences using PCR and a liquid hybridization technique. Vox Sang. 61, 24-29.
    • (1991) Vox Sang. , vol.61 , pp. 24-29
    • Bruisten, S.M.1    Koppelman, M.H.G.M.2    Van Der Poel, C.L.3    Huisman, J.G.4
  • 6
    • 0026725736 scopus 로고
    • Regulation of human monocyte DNA synthesis by colony-stimulating factors, cytokines, and cyclic adenosine monophosphate
    • Cheung, D. L., and Hamilton, J. A. (1992). Regulation of human monocyte DNA synthesis by colony-stimulating factors, cytokines, and cyclic adenosine monophosphate. Blood 79, 1972-1981.
    • (1992) Blood , vol.79 , pp. 1972-1981
    • Cheung, D.L.1    Hamilton, J.A.2
  • 7
    • 0028842207 scopus 로고
    • Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
    • Connor, R. I., Kuan Chen, B., Choe, S., and Landau, N. R. (1995). Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology 206, 935-944.
    • (1995) Virology , vol.206 , pp. 935-944
    • Connor, R.I.1    Kuan Chen, B.2    Choe, S.3    Landau, N.R.4
  • 8
    • 0028798332 scopus 로고
    • Syncytium-inducing (SI) phenotype suppression at seroconversion after intramuscular inoculation of a non-syncytium inducing/SI phenotypically mixed human immunodeficiency virus population
    • Cornelissen, M., Mulder-Kampinga, G. A., Veenstra, J., Zorgdrager, F., Kuiken, C. L., Hartman, S., Dekker, J., Van der Hoek, L., Sol, C., Coutinho, R. A., and Goudsmit, J. (1995). Syncytium-inducing (SI) phenotype suppression at seroconversion after intramuscular inoculation of a non-syncytium inducing/SI phenotypically mixed human immunodeficiency virus population. J. Virol. 69, 1810-1818.
    • (1995) J. Virol. , vol.69 , pp. 1810-1818
    • Cornelissen, M.1    Mulder-Kampinga, G.A.2    Veenstra, J.3    Zorgdrager, F.4    Kuiken, C.L.5    Hartman, S.6    Dekker, J.7    Van Der Hoek, L.8    Sol, C.9    Coutinho, R.A.10    Goudsmit, J.11
  • 9
    • 0019955814 scopus 로고
    • Isolation of functionally different human monocytes by counter-flow centrifugation elutriation
    • Figdor, C. G., Bont, W. S., Touw, I., De Roos, J., Roosnek, E. E., and De Vries, J. (1982). Isolation of functionally different human monocytes by counter-flow centrifugation elutriation. Blood 60, 46-54.
    • (1982) Blood , vol.60 , pp. 46-54
    • Figdor, C.G.1    Bont, W.S.2    Touw, I.3    De Roos, J.4    Roosnek, E.E.5    De Vries, J.6
  • 11
    • 0027948924 scopus 로고
    • HIV-1 macrophage-tropism is determined at multiple steps of the viral replication cycle
    • Fouchier, R. A. M., Brouwer, M., Kootstra, N. A., Huisman, J. G., and Schuitemaker, H. (1994). HIV-1 macrophage-tropism is determined at multiple steps of the viral replication cycle. J. Clin. Invest. 94, 1806-1814.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1806-1814
    • Fouchier, R.A.M.1    Brouwer, M.2    Kootstra, N.A.3    Huisman, J.G.4    Schuitemaker, H.5
  • 12
    • 0030747461 scopus 로고    scopus 로고
    • HIV-1 infection of non-dividing cells: Evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import
    • Fouchier, R. A. M., Meyer, B. E., Simon, J. H. M., Fischer, U., and Malim, M. H. (1997). HIV-1 infection of non-dividing cells: Evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import. EMBO J. 16, 4531-4539.
    • (1997) EMBO J. , vol.16 , pp. 4531-4539
    • Fouchier, R.A.M.1    Meyer, B.E.2    Simon, J.H.M.3    Fischer, U.4    Malim, M.H.5
  • 13
    • 0031472241 scopus 로고    scopus 로고
    • Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection
    • Freed, E. O., Englund, G., Maldarelli, F., and Martin, M. A. (1997). Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection. Cell 88, 171-174.
    • (1997) Cell , vol.88 , pp. 171-174
    • Freed, E.O.1    Englund, G.2    Maldarelli, F.3    Martin, M.A.4
  • 14
    • 0029062117 scopus 로고
    • Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection
    • Freed, E. O., Englund, G., and Martin, M. (1995). Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection. J. Virol, 69, 3949-3954.
    • (1995) J. Virol , vol.69 , pp. 3949-3954
    • Freed, E.O.1    Englund, G.2    Martin, M.3
  • 15
    • 0030987672 scopus 로고    scopus 로고
    • HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway
    • Gallay, P., Hope, T., Chin, D., and Trono, D. (1997). HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway. Proc. Natl. Acad. Sci. USA 94, 9825-9830.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9825-9830
    • Gallay, P.1    Hope, T.2    Chin, D.3    Trono, D.4
  • 16
    • 0030065395 scopus 로고    scopus 로고
    • Role of the karyopherin pathway in HIV-1 nuclear import
    • Gallay, P., Stitt, V., Mundy, C., Oettinger, M., and Trono, D. (1996). Role of the karyopherin pathway in HIV-1 nuclear import. J. Virol. 70, 1027-1032.
    • (1996) J. Virol. , vol.70 , pp. 1027-1032
    • Gallay, P.1    Stitt, V.2    Mundy, C.3    Oettinger, M.4    Trono, D.5
  • 17
    • 0028821383 scopus 로고
    • HIV-1 infection of non-dividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator
    • Gallay, P., Swingler, S., Aiken, C., and Trono, D. (1995). HIV-1 infection of non-dividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator. Cell 80, 379-388.
    • (1995) Cell , vol.80 , pp. 379-388
    • Gallay, P.1    Swingler, S.2    Aiken, C.3    Trono, D.4
  • 20
    • 0032031443 scopus 로고    scopus 로고
    • Proliferation dependent replication in primary macrophages of macrophage-tropic HIV-1 variants
    • Kootstra, N. A., and Schuitemaker, H. (1998). Proliferation dependent replication in primary macrophages of macrophage-tropic HIV-1 variants. AIDS Res. Hum. Retroviruses 14, 339-345.
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , pp. 339-345
    • Kootstra, N.A.1    Schuitemaker, H.2
  • 21
    • 0027162620 scopus 로고
    • Human immunodeficiency virus type 1 DNA synthesis, integration, and efficient viral replication in growth-arrested T cells
    • Li, G., Simm, M., Potash, M. J., and Volsky, D. J. (1993). Human immunodeficiency virus type 1 DNA synthesis, integration, and efficient viral replication in growth-arrested T cells. J. Virol. 67, 3969-3977.
    • (1993) J. Virol. , vol.67 , pp. 3969-3977
    • Li, G.1    Simm, M.2    Potash, M.J.3    Volsky, D.J.4
  • 22
    • 0028888369 scopus 로고
    • Multiple determinants for growth of human immunodeficiency virus type 1 in monocyte-macrophages
    • Malykh, A., Reitz, M. S., Louie, A., Hall, L., and Lori, F. (1995). Multiple determinants for growth of human immunodeficiency virus type 1 in monocyte-macrophages. Virology 206, 646-650.
    • (1995) Virology , vol.206 , pp. 646-650
    • Malykh, A.1    Reitz, M.S.2    Louie, A.3    Hall, L.4    Lori, F.5
  • 23
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller, D. G., Adam, M. A., and Miller, A. D. (1990). Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol. Cell. Biol. 10, 4239-4242.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4239-4242
    • Miller, D.G.1    Adam, M.A.2    Miller, A.D.3
  • 24
    • 0030931963 scopus 로고    scopus 로고
    • Stable and efficient gene transfer into retina using HIV-based lentiviral vector
    • Miyoshi, H., Takahashi, M., Gage, F. H., and Verma, I. M. (1997). Stable and efficient gene transfer into retina using HIV-based lentiviral vector. Proc. Natl. Acad. Sci. USA 94, 10319-10323.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10319-10323
    • Miyoshi, H.1    Takahashi, M.2    Gage, F.H.3    Verma, I.M.4
  • 25
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini, L., Blömer, U., Gallay, P., Ory D., Mulligan, R., Gage, F. H., Verma, I. M., and Trono, D. (1996). In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267.
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1    Blömer, U.2    Gallay, P.3    Ory, D.4    Mulligan, R.5    Gage, F.H.6    Verma, I.M.7    Trono, D.8
  • 27
    • 0027158091 scopus 로고
    • Integration of murine leukemia virus DNA depends on mitosis
    • Roe, T. Y., Reynolds, T. C., Yu, G., and Brown, P. O. (1993). Integration of murine leukemia virus DNA depends on mitosis. EMBO J. 12, 2099-2108.
    • (1993) EMBO J. , vol.12 , pp. 2099-2108
    • Roe, T.Y.1    Reynolds, T.C.2    Yu, G.3    Brown, P.O.4
  • 28
    • 0022372670 scopus 로고
    • Enzymatic amplification of b-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia
    • Saiki, R. K., Scharf, S., Faloona, F., Mullis, K. B., Horn, G. T., Erlich, H. A., and Arnheim, N. (1985). Enzymatic amplification of b-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230, 1350-1354.
    • (1985) Science , vol.230 , pp. 1350-1354
    • Saiki, R.K.1    Scharf, S.2    Faloona, F.3    Mullis, K.B.4    Horn, G.T.5    Erlich, H.A.6    Arnheim, N.7
  • 29
    • 0030790535 scopus 로고    scopus 로고
    • Cell proliferation is not required for productive HIV-1 infection of macrophages
    • Schmidtmayerova, H., Nuovo, G. J., and Bukrinsky, M. (1997). Cell proliferation is not required for productive HIV-1 infection of macrophages. Virology 232, 379-384.
    • (1997) Virology , vol.232 , pp. 379-384
    • Schmidtmayerova, H.1    Nuovo, G.J.2    Bukrinsky, M.3
  • 30
    • 0026070668 scopus 로고
    • Monocytotropic human immunodeficiency virus 1 (HIV-1) variants detectable in all stages of HIV infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture
    • Schuitemaker, H., Kootstra, N. A., De Goede, R. E. Y., De Wolf, F., Miedema, F., and Tersmette, M. (1991). Monocytotropic human immunodeficiency virus 1 (HIV-1) variants detectable in all stages of HIV infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture. J. Virol. 65, 356-363.
    • (1991) J. Virol. , vol.65 , pp. 356-363
    • Schuitemaker, H.1    Kootstra, N.A.2    De Goede, R.E.Y.3    De Wolf, F.4    Miedema, F.5    Tersmette, M.6
  • 31
    • 0028559508 scopus 로고
    • Productive HIV-1 infection of macrophages restricted to the cell fraction with proliferative capacity
    • Schuitemaker, H., Kootstra, N. A., Fouchier, R. A. M., Hooibrink, B., and Miedema, F. (1994). Productive HIV-1 infection of macrophages restricted to the cell fraction with proliferative capacity. EMBO J. 13, 5929-5936.
    • (1994) EMBO J. , vol.13 , pp. 5929-5936
    • Schuitemaker, H.1    Kootstra, N.A.2    Fouchier, R.A.M.3    Hooibrink, B.4    Miedema, F.5
  • 32
    • 0029888991 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 replication is blocked prior to reverse transcription and integration in freshly isolated peripheral blood monocytes
    • Sonza, S., Maerz, A., Deacon, N., Meanger, J., Mills, J., and Crowe, S. (1996). Human immunodeficiency virus type 1 replication is blocked prior to reverse transcription and integration in freshly isolated peripheral blood monocytes. J. Virol. 70, 3863-3869.
    • (1996) J. Virol. , vol.70 , pp. 3863-3869
    • Sonza, S.1    Maerz, A.2    Deacon, N.3    Meanger, J.4    Mills, J.5    Crowe, S.6
  • 34
    • 0031950204 scopus 로고    scopus 로고
    • Evolution of syncytium inducing and non-syncytium inducing biological virus clones in relation to replication kinetics during the course of HIV-1 infection
    • Van't Wout, A. B., Blaak, H., Ran, L. J., Brouwer, M., Kuiken, C., and Schuitemaker, H. (1998). Evolution of syncytium inducing and non-syncytium inducing biological virus clones in relation to replication kinetics during the course of HIV-1 infection. J. Virol. 72, 5099-5107.
    • (1998) J. Virol. , vol.72 , pp. 5099-5107
    • Van't Wout, A.B.1    Blaak, H.2    Ran, L.J.3    Brouwer, M.4    Kuiken, C.5    Schuitemaker, H.6
  • 35
    • 0004007632 scopus 로고
    • (R. A. Weiss, N. Teich, J. Coffin, and H. Varmus, Eds.), 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Varmus, H. E., and Swanstrom, R. (1985). "RNA Tumor Viruses" (R. A. Weiss, N. Teich, J. Coffin, and H. Varmus, Eds.), 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1985) RNA Tumor Viruses
    • Varmus, H.E.1    Swanstrom, R.2
  • 36
    • 0028234528 scopus 로고
    • The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes
    • von Schwedler, U., Kornbluth, R. S., and Trono, D. (1994). The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes. Proc. Natl. Acad. Sci. USA 91, 6992-6996.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6992-6996
    • Von Schwedler, U.1    Kornbluth, R.S.2    Trono, D.3
  • 37
    • 0025720570 scopus 로고
    • Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes
    • Weinberg, J. B., Matthews, T. J., Cullen, B. R., and Malim, M. H. (1991). Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes. J. Exp. Med. 174, 1477-1482.
    • (1991) J. Exp. Med. , vol.174 , pp. 1477-1482
    • Weinberg, J.B.1    Matthews, T.J.2    Cullen, B.R.3    Malim, M.H.4
  • 38
    • 0026655258 scopus 로고
    • Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants
    • Westervelt, P., Henkel, T., Trowbridge, D. B., Orenstein, J., Heuser, J., Gendelman, H. E., and Ratner, L. (1992). Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants. J. Virol. 66, 3925-3931.
    • (1992) J. Virol. , vol.66 , pp. 3925-3931
    • Westervelt, P.1    Henkel, T.2    Trowbridge, D.B.3    Orenstein, J.4    Heuser, J.5    Gendelman, H.E.6    Ratner, L.7
  • 39
    • 0025342694 scopus 로고
    • HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure
    • Zack, J. A., Arrigo, S. J., Weitsman, S. R., Go, A. S., Haislip, A., and Chen, I. S. Y. (1990). HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure. Cell 61, 213-222.
    • (1990) Cell , vol.61 , pp. 213-222
    • Zack, J.A.1    Arrigo, S.J.2    Weitsman, S.R.3    Go, A.S.4    Haislip, A.5    Chen, I.S.Y.6
  • 40
    • 0026526144 scopus 로고
    • Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle
    • Zack, J. A., Haislip, A. M., Krogstad, P., and Chen, I. S. Y. (1992). Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle. J. Virol. 66, 1717-1725.
    • (1992) J. Virol. , vol.66 , pp. 1717-1725
    • Zack, J.A.1    Haislip, A.M.2    Krogstad, P.3    Chen, I.S.Y.4
  • 41
    • 0029985975 scopus 로고    scopus 로고
    • Endogenous reverse transcription of human immunodeficiency virus type 1 in physiological microenvironments: An important stage for viral infection of nondividing cells
    • Zhang, H., Dornadula, G., and Pomerantz, R. J. (1996). Endogenous reverse transcription of human immunodeficiency virus type 1 in physiological microenvironments: An important stage for viral infection of nondividing cells. J. Virol. 70, 2809-2824.
    • (1996) J. Virol. , vol.70 , pp. 2809-2824
    • Zhang, H.1    Dornadula, G.2    Pomerantz, R.J.3
  • 42
    • 0027880142 scopus 로고
    • Reverse transcription takes place within extracellular HIV-1 virions: Potential biological significance
    • Zhang, H., Zhang, Y., Spicer, T. P., Abbott, L. Z., Abbott, M., and Poiesz, B. J. (1993). Reverse transcription takes place within extracellular HIV-1 virions: Potential biological significance. AIDS Res. Hum. Retroviruses 9, 1287-1296.
    • (1993) AIDS Res. Hum. Retroviruses , vol.9 , pp. 1287-1296
    • Zhang, H.1    Zhang, Y.2    Spicer, T.P.3    Abbott, L.Z.4    Abbott, M.5    Poiesz, B.J.6


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