Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory rantes mutants

Journal of Biological Chemistry

Volumn 274, Issue 39, 1999, Pages 27505-27512

  Appay, Victor ^a,b   Brown, Anthony ^a   Cribbes, Scott ^a,c   Randle, Eliot ^a,d   Czaplewski, Lloyd G ^a  

^a British Biotech Pharmaceuticals Ltd   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^d Prolifix Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES;

ARTICLE; CELL ACTIVATION; DIMERIZATION; ERYTHROCYTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATION; LEUKEMIA CELL LINE; LEUKOCYTE ACTIVATION; LYMPHOCYTE ACTIVATION; MONOCYTE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

AMINO ACID SUBSTITUTION; CALCIUM; CELL DIVISION; CELL LINE; CHEMOTAXIS, LEUKOCYTE; ERYTHROCYTES; HUMANS; INFLAMMATION; JURKAT CELLS; MACROMOLECULAR SUBSTANCES; MACROPHAGE INFLAMMATORY PROTEIN-1; MONOCYTES; MUTAGENESIS, SITE-DIRECTED; NEUTROPHILS; RANTES; RECOMBINANT PROTEINS; T-LYMPHOCYTES; VARIATION (GENETICS);

EID: 0033600814     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.39.27505     Document Type: Article

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