The role of the 5′ untranslated region (UTR) in glucose-dependent mRNA decay

Yeast

Volumn 19, Issue 10, 2002, Pages 887-902

  De La Cruz, Bernard J ^a   Prieto, Susana ^a   Scheffler, Immo E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

5 UTR; Eukaryotic initiation factors; Glucose repression; mRNA turnover; Saccharomyces cerevisiae; Translation initiation

Indexed keywords

GLUCOSE; IRON PROTEIN SUCCINYLATE; MESSENGER RNA; SUCCINATE DEHYDROGENASE; FUNGAL RNA; INITIATION FACTOR; NONHEME IRON PROTEIN;

5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTURE MEDIUM; ENZYME STABILITY; ENZYME SUBUNIT; FUNGUS GROWTH; HALF LIFE TIME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RNA METABOLISM; RNA STABILITY; RNA TRANSCRIPTION; SACCHAROMYCES CEREVISIAE; TRANSLATION REGULATION; GENETICS; MACROMOLECULE; METABOLISM; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PROTEIN SYNTHESIS;

EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

5' UNTRANSLATED REGIONS; BASE SEQUENCE; BLOTTING, NORTHERN; GLUCOSE; HALF-LIFE; MACROMOLECULAR SUBSTANCES; NONHEME IRON PROTEINS; PEPTIDE INITIATION FACTORS; PROTEIN BIOSYNTHESIS; RNA, FUNGAL; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SUCCINATE DEHYDROGENASE;

EID: 0035983107     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/yea.884     Document Type: Article

References (54)

1. The 5′ terminal oligopyrimidine tract confers translational control on TOP mRNAs in a cell type- and sequence context-dependent manner
2. Vertebrate mRNAs with a 5′-terminal pyrimidine tract are candidates for translational repression in quiescent cells: Characterization of the translational cis-regulatory element
3. Degradation of mRNA in eukaryotes
4. Regulation of glucose utilization in yeast
5. Glucose repression in yeast
6. Iron-responsive elements: Regulatory RNA sequences that control mRNA levels and translation
7. Mutational analysis of the Saccharomyces cerevisiae SNF1 protein kinase and evidence for functional interaction with the SNF4 protein
8. The Control of mRNA Turnover as a Mechanism of Glucose Repression in Saccharomyces cerevisiae
9. Glucose-dependent turnover of the mRNAs encoding succinate dehydrogenase peptides in Saccharomyces cerevisiae: Sequence elements in the 5′ untranslated region of IP mRNA play a dominant role
10. Genetic analysis of glucose regulation in Saccharomyces cerevisiae: Control of transcription versus mRNA turnover
11. Post-transcriptional gene regulatory mechanisms in eukaryotes: An overview
12. Mechanisms of mRNA degradation in eukaryotes
13. mRNA translation in yeast during entry into stationary phase
14. Signal transduction and regulation of translation initiation
15. Yeast carbon catabolite repression
16. Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements
17. A model for the structure and functions of iron-responsive elements
18. The expression of poly(A) binding protein gene is translationally regulated in a growth-dependent fashion through a 5′-terminal oligpyrimidine tract motif
19. Transformation of intact yeast cells treated with alkali cations
20. Improved predictions of secondary structures for RNA
21. S6k
22. The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Ga183 component in the kinase complex
23. Regulation of carbon and phosphate utilization
24. cis-trans Models for post-transcriptional gene regulation
25. Regulating the fate of mRNA: The control of cellular iron metabolism
26. Influences of mRNA secondary structure on initiation by eukaryotic ribosomes
27. A consideration of alternative models for the initiation of translation in eukaryotes
28. The cis-acting sequences responsible for the differential decay of the unstable MFA2 and stable PGK1 transcripts in yeast include the context of the translational start codon
29. Oligopyrimidine tract at the 5′ end of mammalian ribosomal protein mRNAs is required for their translational control
30. Control of mRNA turnover as a mechanism of glucose repression in Saccharomyces cerevisiae
31. Isolation and characterization of a Saccharomyces cerevisiae mutant with a disrupted gene for the IP subunit of succinate dehydrogenase
32. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
33. Mutations causing constitutive invertase synthesis in yeast: Genetic interactions with snf mutations
34. The relationship between eukaryotic translation and mRNA stability. A short upstream open reading frame strongly inhibits translational initiation and greatly accelerates mRNA degradation in the yeast Saccharomyces cerevisiae
35. Inhibition of translational initiation in Saccharomyces cerevisiae by secondary structure: Roles of the stability and position of stem loops in the mRNA leader
36. Expression of the SUC2 gene of Saccharomyces cerevisiae is induced by low levels of glucose
37. Glucose-regulated turnover of mRNA and the influence of poly(A) tail length on half-life
38. Control of messenger RNA stability in higher eukaryotes
39. The influence of 5′ secondary structures upon ribosome binding to mRNA during translation in yeast
40. Upstream region of the SUC2 gene confers regulated expression to a heterologous gene in Saccharomyces cerevisiae
41. Control of mRNA turnover as a mechanism of glucose repression in Succharomyces cererisiae
42. Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae
43. mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E
44. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
45. Heat shock transcription factor activates yeast metallothionein gene expression in response to heat and glucose starvation via distinct signalling pathways
46. Ferritin mRNA translation, structure, and gene transcription during development of animals and plants
47. Regulation of ferritin and transferrin receptor mRNAs
48. Glucose repression in the yeast Saccharomyces cerevisiae
49. Mechanisms and control of mRNA decapping in Saccharomyces cerevisiae
50. Inhibition of translational initiation in the yeast Saccharomyces cerevisiae as a function of the stability and position of hairpin structures in the mRNA leader
51. The eukaryotic mRNA decapping protein Dcp1 interacts physically and functionally with the eIF4F translation initiation complex
52. Deletion of the PAT1 gene affects translation initiation and suppresses a PAB1 gene deletion in yeast
53. On finding all suboptimal foldings of an RNA molecule