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Volumn 15, Issue 5, 2001, Pages 609-615

Sequencing of protease inhibitor therapy: Insights from an analysis of HIV phenotypic resistance in patients failing protease inhibitors

(25)  Kemper, Carol A a,b   Witt, Mallory D c,d   Keiser, Phillip H e   Dubé, Michael P f   Forthal, Donald N g   Leibowitz, Matthew d   Smith, D Scott h   Rigby, Andrew i   Hellmann, Nicholas S j   Lie, Yolanda S j   Leedom, John k   Richman, Douglas i,l   McCutchan, J Allen i   Haubrich, Richard i   Seefried, E L i   Ballard, C m   Yazdani, B e   Martinez, S a   Downing, M n   Yeganeh, M h   more..


Author keywords

Antiretroviral resistance; HIV 1; Phenotypic assay; Protease inhibitor

Indexed keywords

AMPRENAVIR; INDINAVIR; NELFINAVIR; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; VIRUS RNA;

EID: 0035970641     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200103300-00010     Document Type: Article
Times cited : (52)

References (31)
  • 1
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV outpatients Study investigators
    • Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatients Study Investigators. N Engl J Med 1998, 338:853-860.
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella, F.J.1    Delaney, K.M.2    Moorman, A.C.3
  • 2
    • 0442268112 scopus 로고    scopus 로고
    • A controlled trail of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 study team
    • Hammer SM, Squires KE, Hughes MD, et al. A controlled trail of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. N Engl J Med. 1997, 337:725-733.
    • (1997) N Engl J Med , vol.337 , pp. 725-733
    • Hammer, S.M.1    Squires, K.E.2    Hughes, M.D.3
  • 3
    • 0034685037 scopus 로고    scopus 로고
    • Antiretroviral therapy in adults: Updated recommendations of the International AIDS Society - USA Panel
    • Carpenter CC, Cooper DA, Fischl MA, et al. Antiretroviral therapy in adults: Updated recommendations of the International AIDS Society - USA Panel. JAMA 2000, 283:381-390.
    • (2000) JAMA , vol.283 , pp. 381-390
    • Carpenter, C.C.1    Cooper, D.A.2    Fischl, M.A.3
  • 4
    • 0343183245 scopus 로고    scopus 로고
    • Antiretroviral drug resistance testing in adult HIV infection. Recommendations of an international AIDS society-USA panel
    • Hirsch MS, Brun Vezinet F, D'Aquila RT, et al. Antiretroviral drug resistance testing in adult HIV infection. Recommendations of an International AIDS Society-USA Panel. JAMA 2000, 238:2417-2426.
    • (2000) JAMA , vol.238 , pp. 2417-2426
    • Hirsch, M.S.1    Brun Vezinet, F.2    D'Aquila, R.T.3
  • 5
    • 0032103187 scopus 로고    scopus 로고
    • Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients
    • Shafer RW, Winters MA, Palmer S, Merigan TC. Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients. Ann Intern Med 1998, 128:906-911.
    • (1998) Ann Intern Med , vol.128 , pp. 906-911
    • Shafer, R.W.1    Winters, M.A.2    Palmer, S.3    Merigan, T.C.4
  • 6
    • 13344275873 scopus 로고    scopus 로고
    • Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease
    • Patick AK, Mo H, Markowitz M, et al. Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease. Antimicrob Agents Chemother 1996, 40:292-297.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 292-297
    • Patick, A.K.1    Mo, H.2    Markowitz, M.3
  • 8
    • 0031950370 scopus 로고    scopus 로고
    • Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (Norvir) monotherapy
    • Eastman PS, Mittler J, Kelso R, et al. Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (Norvir) monotherapy. J Virol 1998, 72:5154-5164.
    • (1998) J Virol , vol.72 , pp. 5154-5164
    • Eastman, P.S.1    Mittler, J.2    Kelso, R.3
  • 9
    • 0032808202 scopus 로고    scopus 로고
    • The value of patient-reported adherence to antiretroviral therapy in predicting virologic and immunologic response
    • Haubrich RH, Little SJ, Currier JS, et al. The value of patient-reported adherence to antiretroviral therapy in predicting virologic and immunologic response. AIDS 1999, 13: 1099-1107.
    • (1999) AIDS , vol.13 , pp. 1099-1107
    • Haubrich, R.H.1    Little, S.J.2    Currier, J.S.3
  • 10
    • 0033033234 scopus 로고    scopus 로고
    • HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS Clinic: Response to both initial and salvage therapy
    • Deeks S, Hecht F, Swanson M, et al. HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS Clinic: Response to both initial and salvage therapy. AIDS 1999, 13:F35-F43.
    • (1999) AIDS , vol.13 , pp. F35-F43
    • Deeks, S.1    Hecht, F.2    Swanson, M.3
  • 11
    • 0034019566 scopus 로고    scopus 로고
    • A novel phenotypic drug susceptibility assay for human immunodeficiency virus 1
    • Petropoulos CJ, Parkin NT, Limoli KL, et al. A novel phenotypic drug susceptibility assay for human immunodeficiency virus 1. Antimicrob Agents Chemother 2000, 44:920-928.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 920-928
    • Petropoulos, C.J.1    Parkin, N.T.2    Limoli, K.L.3
  • 13
    • 0032750954 scopus 로고    scopus 로고
    • Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle virus assay for patients failing combination therapies
    • Race E, Dam E, Obry V, Paulous S, Clavel F. Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle virus assay for patients failing combination therapies. AIDS 1999, 13:2061-2068.
    • (1999) AIDS , vol.13 , pp. 2061-2068
    • Race, E.1    Dam, E.2    Obry, V.3    Paulous, S.4    Clavel, F.5
  • 14
    • 0343109638 scopus 로고    scopus 로고
    • Genetic correlates of virological response to an indinavir-containing salvage regimen in patients with nelfinavir failure
    • San Diego, April abstract 63
    • Condra JH, Holder DJ, Schleif WA, et al. Genetic correlates of virological response to an indinavir-containing salvage regimen in patients with nelfinavir failure. Third International Workshop on Drug Resistance and Treatment Strategies. San Diego, April 1999 [abstract 63].
    • (1999) Third International Workshop on Drug Resistance and Treatment Strategies
    • Condra, J.H.1    Holder, D.J.2    Schleif, W.A.3
  • 15
    • 0033010748 scopus 로고    scopus 로고
    • Virologic responses to a ritonavir-saquinavir-containing regimen in patients who have previously failed nelfinavir
    • Tebas P, Patick AK, Kane EM, et al. Virologic responses to a ritonavir-saquinavir-containing regimen in patients who have previously failed nelfinavir. AIDS 1999, 13:F23-F28.
    • (1999) AIDS , vol.13 , pp. F23-F28
    • Tebas, P.1    Patick, A.K.2    Kane, E.M.3
  • 16
    • 0003243402 scopus 로고    scopus 로고
    • The efficacy of ritonavir (RTV)/saquinavir (SQV) antiretroviral therapy (ART) in patients who failed nelfinavir (NLV): A multicenter clinical cohort study
    • San Francisco, September abstract 2065
    • Zolopa AR, Tebas P, Gallant J, et al. The efficacy of ritonavir (RTV)/saquinavir (SQV) antiretroviral therapy (ART) in patients who failed nelfinavir (NLV): A multicenter clinical cohort study. 39th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, September 1999 [abstract 2065].
    • (1999) 39th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Zolopa, A.R.1    Tebas, P.2    Gallant, J.3
  • 17
    • 85103140288 scopus 로고    scopus 로고
    • Phenotypic changes in drug susceptibility associated with failure of human immunode-ficiency virus type 1 (HIV-1) triple combination therapy
    • Parkin NT, Lie YS, Hellmann NS, et al. Phenotypic changes in drug susceptibility associated with failure of human immunode-ficiency virus type 1 (HIV-1) triple combination therapy. J Infect Dis 1999, 179:1375-1381.
    • (1999) J Infect Dis , vol.179 , pp. 1375-1381
    • Parkin, N.T.1    Lie, Y.S.2    Hellmann, N.S.3
  • 18
    • 0034639490 scopus 로고    scopus 로고
    • Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens
    • Havlir DV, Hellmann NS, Petropoulus CJ, et al. Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens. JAMA 2000, 283:229-234.
    • (2000) JAMA , vol.283 , pp. 229-234
    • Havlir, D.V.1    Hellmann, N.S.2    Petropoulus, C.J.3
  • 19
    • 0034639473 scopus 로고    scopus 로고
    • Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy. Trilege (Agence nationale de recherches sur le Sida 072 study team)
    • Descamps D, Flandre P, Calvez V, et al. Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy. Trilege (Agence Nationale de Recherches sur le SIDA 072 Study Team). JAMA 2000, 283: 201-211.
    • (2000) JAMA , vol.283 , pp. 201-211
    • Descamps, D.1    Flandre, P.2    Calvez, V.3
  • 20
    • 0032869255 scopus 로고    scopus 로고
    • HIV-1 evolution under pressure of protease inhibitors: Climbing the stairs of viral fitness
    • Berkhout B. HIV-1 evolution under pressure of protease inhibitors: Climbing the stairs of viral fitness. J Biomed Sci 1999, 6:298-305.
    • (1999) J Biomed Sci , vol.6 , pp. 298-305
    • Berkhout, B.1
  • 21
    • 15444377672 scopus 로고    scopus 로고
    • Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
    • Molla A, Korneyeva M, Gao Q, Vasavanonda S, et al. Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. Nature Med 1996, 2:760-766.
    • (1996) Nature Med , vol.2 , pp. 760-766
    • Molla, A.1    Korneyeva, M.2    Gao, Q.3    Vasavanonda, S.4
  • 22
    • 0033281851 scopus 로고    scopus 로고
    • Failure of HIV-1 protease inhibitors to fully suppress viral replication. Implications for salvage therapy
    • Deeks SG. Failure of HIV-1 protease inhibitors to fully suppress viral replication. Implications for salvage therapy. Adv Exp Med Biol 1999, 458:175-182.
    • (1999) Adv Exp Med Biol , vol.458 , pp. 175-182
    • Deeks, S.G.1
  • 23
    • 0032990266 scopus 로고    scopus 로고
    • Novel four-drug salvage treatment regimens after failure of a human immunode-fiency virus type 1 protease inhibitor-containing regimen: Antiviral activity and correlation of baseline phenotype drug susceptibility with virologic outcome
    • Deeks SG, Hellmann NS, Grant RM, et al. Novel four-drug salvage treatment regimens after failure of a human immunode-fiency virus type 1 protease inhibitor-containing regimen: antiviral activity and correlation of baseline phenotype drug susceptibility with virologic outcome. J Infect Dis 1999, 179:1375-1381.
    • (1999) J Infect Dis , vol.179 , pp. 1375-1381
    • Deeks, S.G.1    Hellmann, N.S.2    Grant, R.M.3
  • 24
    • 0030317870 scopus 로고    scopus 로고
    • The effect of high-dose saquinavir on viral load and CD4+ T-cell counts in HIV-infected patients
    • Schapiro JM, Winters MA, Stewart F, et al. The effect of high-dose saquinavir on viral load and CD4+ T-cell counts in HIV-infected patients. Ann Intern Med 1996, 124: 1039-1059.
    • (1996) Ann Intern Med , vol.124 , pp. 1039-1059
    • Schapiro, J.M.1    Winters, M.A.2    Stewart, F.3
  • 26
    • 0033606540 scopus 로고    scopus 로고
    • Drug resistance genotyping in HIV-1 therapy: The VIRADAPT randomized controlled trail
    • Durant J, Clevenbergh P, Halfon P, et al. Drug resistance genotyping in HIV-1 therapy: The VIRADAPT randomized controlled trail. Lancet 1999, 353:2195-2199.
    • (1999) Lancet , vol.353 , pp. 2195-2199
    • Durant, J.1    Clevenbergh, P.2    Halfon, P.3
  • 27
    • 0001287189 scopus 로고    scopus 로고
    • A pilot study of the short-term effects of antiretroviral management based on plasma genotypic antiretroviral resistance testing (GART) in patients failing antiretroviral therapy
    • Chicago, January abstract LB8
    • Baxter JD, Mayers DL, Wentworth DN, Neoton JD, Merigan TC. A pilot study of the short-term effects of antiretroviral management based on plasma genotypic antiretroviral resistance testing (GART) in patients failing antiretroviral therapy. Sixth Conference on Retroviruses and Opportunistic Infections. Chicago, January 1999 [abstract LB8].
    • (1999) Sixth Conference on Retroviruses and Opportunistic Infections
    • Baxter, J.D.1    Mayers, D.L.2    Wentworth, D.N.3    Neoton, J.D.4    Merigan, T.C.5
  • 28
    • 0344593433 scopus 로고    scopus 로고
    • The relation between baseline HIV drug resistance and response to antiretroviral therapy: Re-analysis of retrospective and prospective studies using a standardized data analysis plan
    • DeGrutolla V, Dix L, D'Aquilar, et al. The relation between baseline HIV drug resistance and response to antiretroviral therapy: Re-analysis of retrospective and prospective studies using a standardized data analysis plan. Antiviral Ther 2000, 5:43-50.
    • (2000) Antiviral Ther , vol.5 , pp. 43-50
    • DeGrutolla, V.1    Dix, L.2    D'Aquilar3
  • 29
    • 0003276336 scopus 로고    scopus 로고
    • Phenotypic resistance testing significantly improves response to therapy: A randomized trail (VIRA 3001)
    • San Francisco, January abstract 237
    • Cohen C, Hunt S, Sension M, et al. Phenotypic resistance testing significantly improves response to therapy: A randomized trail (VIRA 3001). Seventh Conference on Retroviruses and Opportunistic Infections. San Francisco, January 2000 [abstract 237].
    • (2000) Seventh Conference on Retroviruses and Opportunistic Infections
    • Cohen, C.1    Hunt, S.2    Sension, M.3
  • 31
    • 0033615280 scopus 로고    scopus 로고
    • Reduced antiretroviral drug susceptibility among patients with primary HIV infection
    • Little SJ, Daar ES, D'Aquila RT, et al. Reduced antiretroviral drug susceptibility among patients with primary HIV infection. JAMA 1999, 282:1142-1149.
    • (1999) JAMA , vol.282 , pp. 1142-1149
    • Little, S.J.1    Daar, E.S.2    D'Aquila, R.T.3


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