-
1
-
-
0028246688
-
(R)-Methanandamide: A chiral novel anandamide possessing higher potency and metabolic stability
-
Abadji V., Lin S., Taha G., Griffin G., Stevenson L. A., Pertwee R. G., and Makriyannis A. (1994) (R)-Methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability. J. Med. Chem. 37, 1889-1893.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 1889-1893
-
-
Abadji, V.1
Lin, S.2
Taha, G.3
Griffin, G.4
Stevenson, L.A.5
Pertwee, R.G.6
Makriyannis, A.7
-
2
-
-
0031028923
-
Isolation and expression of a mouse CB1 cannabinoid receptor gene
-
Abood M. E., Ditto K. E., Noel M. A., Showalter V. M., and Tao Q. (1997) Isolation and expression of a mouse CB1 cannabinoid receptor gene. Biochem. Pharmacol. 53, 207-214.
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 207-214
-
-
Abood, M.E.1
Ditto, K.E.2
Noel, M.A.3
Showalter, V.M.4
Tao, Q.5
-
3
-
-
0027506471
-
The probable arrangement of the helices in G protein-coupled receptors
-
Baldwin J. M. (1993) The probable arrangement of the helices in G protein-coupled receptors. EMBO J. 12, 1693-1703.
-
(1993)
EMBO J.
, vol.12
, pp. 1693-1703
-
-
Baldwin, J.M.1
-
4
-
-
0029586743
-
Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1
-
Bouaboula M., Poinot-Chazel C., Bourrie B., Canat X., Calandra B., Rinaldi-Carmona M., Le Fur G., and Casellas P. (1995) Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1. Biochem. J. 312, 637-641.
-
(1995)
Biochem. J.
, vol.312
, pp. 637-641
-
-
Bouaboula, M.1
Poinot-Chazel, C.2
Bourrie, B.3
Canat, X.4
Calandra, B.5
Rinaldi-Carmona, M.6
Le Fur, G.7
Casellas, P.8
-
5
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
-
Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72, 248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
6
-
-
0029078977
-
Construction of a 3D model of the cannabinoid CB1 receptor: Determination of helix ends and helix orientation
-
Bramblett R. D., Panu A. M., Ballesteros J. A., and Reggio P. H. (1995) Construction of a 3D model of the cannabinoid CB1 receptor: determination of helix ends and helix orientation. Life Sci. 56, 1971-1982.
-
(1995)
Life Sci.
, vol.56
, pp. 1971-1982
-
-
Bramblett, R.D.1
Panu, A.M.2
Ballesteros, J.A.3
Reggio, P.H.4
-
7
-
-
0003015977
-
Functional significance of cannabinoid receptors in brain
-
(Pertwee R. G., ed). Academic Press, San Diego
-
Deadwyler S. A., Hampson R. E., and Childers S. R. (1995) Functional significance of cannabinoid receptors in brain, in Cannabinoid Receptors (Pertwee R. G., ed), pp. 205-231. Academic Press, San Diego.
-
(1995)
Cannabinoid Receptors
, pp. 205-231
-
-
Deadwyler, S.A.1
Hampson, R.E.2
Childers, S.R.3
-
8
-
-
0024263922
-
Determination and characterization of a cannabinoid receptor in rat brain
-
Devane W. A., Francis A. D. III, Johnson M. R., Melvin L. S., and Howlett A. C. (1988) Determination and characterization of a cannabinoid receptor in rat brain. Mol. Pharmacol. 34, 605-613.
-
(1988)
Mol. Pharmacol.
, vol.34
, pp. 605-613
-
-
Devane, W.A.1
Francis III, A.D.2
Johnson, M.R.3
Melvin, L.S.4
Howlett, A.C.5
-
9
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane W. A., Hanuš L., Breuer A., Pertwee R. G., Stevenson L. A., Griffin G., Gibson D., Mandelbaum A., Etinger A., and Mechoulam R. (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258, 1946-1949.
-
(1992)
Science
, vol.258
, pp. 1946-1949
-
-
Devane, W.A.1
Hanuš, L.2
Breuer, A.3
Pertwee, R.G.4
Stevenson, L.A.5
Griffin, G.6
Gibson, D.7
Mandelbaum, A.8
Etinger, A.9
Mechoulam, R.10
-
10
-
-
0022509199
-
Cannabinoid pharmacology
-
Dewey W. L. (1986) Cannabinoid pharmacology. Pharmacol. Rev. 38, 151-178.
-
(1986)
Pharmacol. Rev.
, vol.38
, pp. 151-178
-
-
Dewey, W.L.1
-
11
-
-
0027064626
-
Cannabinoid agonists stimulate both receptor- and non-receptor-mediated signal transduction pathways in cells transfected with and expressing cannabinoid receptor clones
-
Felder C. C., Veluz J. S., Williams H. L., Briley E. M., and Matsuda L. A. (1992) Cannabinoid agonists stimulate both receptor- and non-receptor-mediated signal transduction pathways in cells transfected with and expressing cannabinoid receptor clones. Mol. Pharmacol. 42, 838-845.
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 838-845
-
-
Felder, C.C.1
Veluz, J.S.2
Williams, H.L.3
Briley, E.M.4
Matsuda, L.A.5
-
12
-
-
0027402090
-
Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345
-
Fong T. M., Cascieri M. A., Yu H., Bansal A., Swain C., and Strader C. D. (1994) Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345. Nature 362, 350-353.
-
(1994)
Nature
, vol.362
, pp. 350-353
-
-
Fong, T.M.1
Cascieri, M.A.2
Yu, H.3
Bansal, A.4
Swain, C.5
Strader, C.D.6
-
13
-
-
0024847889
-
Site directed mutagenesis of m1 muscarinic acetylcholine receptors: Conserved aspartic acids play important roles in receptor function
-
Fraser C. M., Wang C.-D., Robinson D. A., Gocayne J. D., and Venter J. C. (1989) Site directed mutagenesis of m1 muscarinic acetylcholine receptors: conserved aspartic acids play important roles in receptor function. Mol. Pharmacol. 36, 840-847.
-
(1989)
Mol. Pharmacol.
, vol.36
, pp. 840-847
-
-
Fraser, C.M.1
Wang, C.-D.2
Robinson, D.A.3
Gocayne, J.D.4
Venter, J.C.5
-
14
-
-
0025878961
-
Molecular cloning of a human cannabinoid receptor which is also expressed in testis
-
Gérard C. M., Mollereau C., Vassart G., and Parmentier M. (1991) Molecular cloning of a human cannabinoid receptor which is also expressed in testis. Biochem. J. 279, 129-134.
-
(1991)
Biochem. J.
, vol.279
, pp. 129-134
-
-
Gérard, C.M.1
Mollereau, C.2
Vassart, G.3
Parmentier, M.4
-
16
-
-
0029846519
-
Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor
-
Huffman J. W., Yu S., Showalter V., Abood M. E., Bramblett R. D., and Reggio P. H. (1996) Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor. J. Med. Chem. 39, 3875-3877.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 3875-3877
-
-
Huffman, J.W.1
Yu, S.2
Showalter, V.3
Abood, M.E.4
Bramblett, R.D.5
Reggio, P.H.6
-
17
-
-
0026511304
-
Distribution of cannabinoid receptors in rat brain determined with aminoalkylindoles
-
Jansen E. M., Haycock D. A., Ward S. J., and Seybold V. S. (1992) Distribution of cannabinoid receptors in rat brain determined with aminoalkylindoles. Brain Res. 575, 93-102.
-
(1992)
Brain Res.
, vol.575
, pp. 93-102
-
-
Jansen, E.M.1
Haycock, D.A.2
Ward, S.J.3
Seybold, V.S.4
-
18
-
-
0029657910
-
The role of Asp 578 in maintaining the inactive conformation of the human lutropin/choriogonadotropin receptor
-
Kosugi S., Mori T., and Shenker A. (1996) The role of Asp 578 in maintaining the inactive conformation of the human lutropin/choriogonadotropin receptor. J. Biol. Chem. 271, 31813-31817.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31813-31817
-
-
Kosugi, S.1
Mori, T.2
Shenker, A.3
-
19
-
-
0026603679
-
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells
-
Mackie K. and Hille B. (1992) Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc. Natl. Acad. Sci. USA 89, 3825-3829.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 3825-3829
-
-
Mackie, K.1
Hille, B.2
-
20
-
-
0002866945
-
Structural requirements for cannabinoid receptor probes
-
(Pertwee R. G., ed). Academic Press, San Diego
-
Martin B. R., Thomas B. F., and Razdan R. K. (1995) Structural requirements for cannabinoid receptor probes, in Cannabinoid Receptors (Pertwee R. G., ed), pp. 36-79. Academic Press, San Diego.
-
(1995)
Cannabinoid Receptors
, pp. 36-79
-
-
Martin, B.R.1
Thomas, B.F.2
Razdan, R.K.3
-
21
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda L. A., Lolait S. J., Brownstein M. J., Young A. C., and Bonner T.I. (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561-564.
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
22
-
-
0026800892
-
The cloning of a family of genes that encode the melanocortin receptors
-
Mountjoy K. G., Robbins L. S., Mortrud M. T., and Cone R. D. (1992) The cloning of a family of genes that encode the melanocortin receptors. Science 257, 1248-1251.
-
(1992)
Science
, vol.257
, pp. 1248-1251
-
-
Mountjoy, K.G.1
Robbins, L.S.2
Mortrud, M.T.3
Cone, R.D.4
-
23
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro S., Thomas K. L., and Abu-Shaar M. (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 365, 61-65.
-
(1993)
Nature
, vol.365
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
24
-
-
0028926576
-
Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms
-
Noda K., Saad Y., Kinoshita A., Boyle T. P., Graham R. M., Husain A., and Kamik S. S. (1995) Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms. J. Biol. Chem. 270, 2284-2289.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2284-2289
-
-
Noda, K.1
Saad, Y.2
Kinoshita, A.3
Boyle, T.P.4
Graham, R.M.5
Husain, A.6
Kamik, S.S.7
-
25
-
-
0022885592
-
Structure-activity relationships in cannabinoids
-
Razdan R. K. (1986) Structure-activity relationships in cannabinoids. Pharmacol. Rev. 38, 75-149.
-
(1986)
Pharmacol. Rev.
, vol.38
, pp. 75-149
-
-
Razdan, R.K.1
-
26
-
-
0023464472
-
Molecular determinants for cannabinoid activity: Refinement of a molecular reactivity template
-
(Rapaka R. S. and Makriyannis A., eds). U.S. Government Printing Office, Washington, D.C.
-
Reggio P. H. (1987) Molecular determinants for cannabinoid activity: refinement of a molecular reactivity template, in NIDA Research Monograph, Vol. 79 (Rapaka R. S. and Makriyannis A., eds), pp. 82-95. U.S. Government Printing Office, Washington, D.C.
-
(1987)
NIDA Research Monograph, Vol. 79
, vol.79
, pp. 82-95
-
-
Reggio, P.H.1
-
27
-
-
0343177634
-
Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin
-
Sakmar T. P., Franke R. R., and Khorana H. G. (1989) Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin. Proc. Natl. Acad. Sci. USA 86, 8309-8313.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 8309-8313
-
-
Sakmar, T.P.1
Franke, R.R.2
Khorana, H.G.3
-
30
-
-
0025300739
-
A computergraphic investigation into the pharmacological role of the THC-cannabinoid phenolic moiety
-
Semus S. F. and Martin B. R. (1990) A computergraphic investigation into the pharmacological role of the THC-cannabinoid phenolic moiety. Life Sci. 46, 1781-1785.
-
(1990)
Life Sci.
, vol.46
, pp. 1781-1785
-
-
Semus, S.F.1
Martin, B.R.2
-
31
-
-
0029866824
-
A lysine residue of the cannabinoid receptor is critical to receptor recognition by several agonists but not WIN 55,212-2
-
Song Z.-H. and Bonner T. I. (1996) A lysine residue of the cannabinoid receptor is critical to receptor recognition by several agonists but not WIN 55,212-2. Mol. Pharmacol. 49, 891-896.
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 891-896
-
-
Song, Z.-H.1
Bonner, T.I.2
-
32
-
-
0029064111
-
Common cannabimimetic pharmacophoric requirements between aminoalkyl indoles and classical cannabinoids
-
Xie X.-Q., Eissenstat M., and Makriyannis A. (1995) Common cannabimimetic pharmacophoric requirements between aminoalkyl indoles and classical cannabinoids. Life Sci. 56, 1963-1970.
-
(1995)
Life Sci.
, vol.56
, pp. 1963-1970
-
-
Xie, X.-Q.1
Eissenstat, M.2
Makriyannis, A.3
-
33
-
-
15844374570
-
The conformational properties of the highly selective cannabinoid receptor ligand CP-55,940
-
Xie X.-Q., Melvin L. S., and Makriyannis A. (1996) The conformational properties of the highly selective cannabinoid receptor ligand CP-55,940. J. Biol. Chem. 271, 10640-10647.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10640-10647
-
-
Xie, X.-Q.1
Melvin, L.S.2
Makriyannis, A.3
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