-
1
-
-
0029151644
-
Characterization of a delta opioid receptor in rat pheochromocytoma cells
-
Abood ME and Tao Q (1995) Characterization of a delta opioid receptor in rat pheochromocytoma cells. J Pharmacol Exp Ther 274:1566-1573.
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 1566-1573
-
-
Abood, M.E.1
Tao, Q.2
-
2
-
-
77957055780
-
Integrated methods for the construction of three dimensional models and computational probing of structure function relations in G protein-coupled receptors
-
(Conn PM and Sealfon SM eds), Academic Press, San Diego
-
Ballesteros JA and Weinstein H (1995) Integrated methods for the construction of three dimensional models and computational probing of structure function relations in G protein-coupled receptors, in Methods in Neuroscience (Conn PM and Sealfon SM eds) pp 366-428, Academic Press, San Diego.
-
(1995)
Methods in Neuroscience
, pp. 366-428
-
-
Ballesteros, J.A.1
Weinstein, H.2
-
3
-
-
0029078977
-
Construction of a 3D model of the cannabinoid CB1 receptor: Determination of helix ends and helix orientation
-
Bramblett RD, Panu AM, Ballesteros JA and Reggio PH (1995) Construction of a 3D model of the cannabinoid CB1 receptor: Determination of helix ends and helix orientation. Life Sci 56:1971-1982.
-
(1995)
Life Sci
, vol.56
, pp. 1971-1982
-
-
Bramblett, R.D.1
Panu, A.M.2
Ballesteros, J.A.3
Reggio, P.H.4
-
4
-
-
0015861774
-
Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (IC50) on an enzymatic reaction
-
Cheng YC and Prusoff WH (1973) Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (IC50) on an enzymatic reaction. Biochem Pharmacol 22:3099-3108.
-
(1973)
Biochem Pharmacol
, vol.22
, pp. 3099-3108
-
-
Cheng, Y.C.1
Prusoff, W.H.2
-
5
-
-
0031972779
-
Ligand binding and modulation of cyclic AMP levels depends on the chemical nature of residue 192 of the human cannabinoid receptor 1
-
Chin C, Abadji V, Lucas-Lenard J and Kendall D (1998) Ligand binding and modulation of cyclic AMP levels depends on the chemical nature of residue 192 of the human cannabinoid receptor 1. J Neurochem 70:366-373.
-
(1998)
J Neurochem
, vol.70
, pp. 366-373
-
-
Chin, C.1
Abadji, V.2
Lucas-Lenard, J.3
Kendall, D.4
-
6
-
-
0026592569
-
Pharmacological profile of a series of bicyclic cannabinoid analogs: Classification as cannabimimetic agents
-
Compton DR, Johnson MR, Melvin LS and Martin BR (1992) Pharmacological profile of a series of bicyclic cannabinoid analogs: Classification as cannabimimetic agents. J Pharmacol Exp Ther 260:201-209.
-
(1992)
J Pharmacol Exp Ther
, vol.260
, pp. 201-209
-
-
Compton, D.R.1
Johnson, M.R.2
Melvin, L.S.3
Martin, B.R.4
-
7
-
-
0027185227
-
Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediate signal transduction
-
Felder CC, Briley EM, Axelrod J, Simpson JT, Mackie K and Devane WA (1993) Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediate signal transduction. Proc Natl Acad Sci USA 90:7656-7660.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7656-7660
-
-
Felder, C.C.1
Briley, E.M.2
Axelrod, J.3
Simpson, J.T.4
Mackie, K.5
Devane, W.A.6
-
8
-
-
0029118444
-
Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors
-
Felder CC, Joyce KE, Briley EM, Mansouri J, Mackie K, Blond O, Lai Y, Ma AL and Mitchell RL (1995) Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. Mol Pharmacol 48:443-450.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 443-450
-
-
Felder, C.C.1
Joyce, K.E.2
Briley, E.M.3
Mansouri, J.4
Mackie, K.5
Blond, O.6
Lai, Y.7
Ma, A.L.8
Mitchell, R.L.9
-
9
-
-
0021722983
-
Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes
-
Howlett AC and Fleming RM (1984) Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes. Mol Pharmacol 26:532-538.
-
(1984)
Mol Pharmacol
, vol.26
, pp. 532-538
-
-
Howlett, A.C.1
Fleming, R.M.2
-
10
-
-
0029846519
-
Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor
-
Huffman JW, Yu S, Showalter V, Abood ME, Wiley JL, Compton DR, Martin BR, Bramblett RD and Reggio PH (1996) Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor. J Med Chem 39:3875-3877.
-
(1996)
J Med Chem
, vol.39
, pp. 3875-3877
-
-
Huffman, J.W.1
Yu, S.2
Showalter, V.3
Abood, M.E.4
Wiley, J.L.5
Compton, D.R.6
Martin, B.R.7
Bramblett, R.D.8
Reggio, P.H.9
-
12
-
-
0026603679
-
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells
-
Mackie K and Hille B (1992) Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc Natl Acad Sci. USA 89:3825-3829.
-
(1992)
Proc Natl Acad Sci. USA
, vol.89
, pp. 3825-3829
-
-
Mackie, K.1
Hille, B.2
-
13
-
-
0028823316
-
Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with the rat brain cannabinoid receptor
-
Mackie K, Lai Y, Westenbroek R and Mitchell R (1995) Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with the rat brain cannabinoid receptor. J Neurosci. 15: 6552-6561.
-
(1995)
J Neurosci.
, vol.15
, pp. 6552-6561
-
-
Mackie, K.1
Lai, Y.2
Westenbroek, R.3
Mitchell, R.4
-
14
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda LA, Lolait SJ, Brownstein MJ, Young AC and Bonner TI (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564.
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
15
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro S, Thomas KL and Abu-Shaar M (1993) Molecular characterization of a peripheral receptor for Cannabinoids. Nature 365:61-65.
-
(1993)
Nature
, vol.365
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
16
-
-
0032101590
-
High level expression of the human CB2 cannabinoid receptor using a baculovirus system
-
Nowell KW, Pettit DAD, Cabral WA, H. W. Zimmerman J, Abood ME and Cabral GA (1998) High level expression of the human CB2 cannabinoid receptor using a baculovirus system. Biochem Pharmacol 55:1893-1905.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1893-1905
-
-
Nowell, K.W.1
Pettit, D.A.D.2
Cabral, W.A.3
H W Zimmerman, J.4
Abood, M.E.5
Cabral, G.A.6
-
17
-
-
0002014756
-
Site-directed mutagenesis in one day with >80% efficiency
-
Papworth C, Bauer J, Braman J and Wright D (1996) Site-directed mutagenesis in one day with >80% efficiency. Strategies 9:3-4.
-
(1996)
Strategies
, vol.9
, pp. 3-4
-
-
Papworth, C.1
Bauer, J.2
Braman, J.3
Wright, D.4
-
18
-
-
0004300890
-
-
University of California, San Francisco
-
Pearlman D, Case D, Caldwell J, Seibel G, Singh U, Weiner P and Kollman P (1991) Amber 4.0. University of California, San Francisco.
-
(1991)
Amber 4.0
-
-
Pearlman, D.1
Case, D.2
Caldwell, J.3
Seibel, G.4
Singh, U.5
Weiner, P.6
Kollman, P.7
-
19
-
-
0344096422
-
What is the bioactive conformation of amino-alkylindoles at the CB1 receptor? insights gained from E and Z napthylidene indenes
-
Stone Mountain, GA
-
Reggio PH, Basu-Dutt S, Hurst DP, Patel MJ, Seltzman HH and Thomas BF (1997) What is the bioactive conformation of amino-alkylindoles at the CB1 receptor? Insights gained from E and Z napthylidene indenes, in Symposium on the Cannabinoids, International Cannabinoid Research Society p 47, Stone Mountain, GA.
-
(1997)
Symposium on the Cannabinoids, International Cannabinoid Research Society
, pp. 47
-
-
Reggio, P.H.1
Basu-Dutt, S.2
Hurst, D.P.3
Patel, M.J.4
Seltzman, H.H.5
Thomas, B.F.6
-
20
-
-
0014127723
-
A graphic method for the determination and presentation of binding parameters in a complex system
-
Rosenthal HE (1967) A graphic method for the determination and presentation of binding parameters in a complex system. Anal Biochem 20:525-537.
-
(1967)
Anal Biochem
, vol.20
, pp. 525-537
-
-
Rosenthal, H.E.1
-
21
-
-
84969001783
-
The attractions of proteins for small molecules and ions
-
Scatchard G (1951) The attractions of proteins for small molecules and ions. Ann NY Acad Sci 51:670-672.
-
(1951)
Ann NY Acad Sci
, vol.51
, pp. 670-672
-
-
Scatchard, G.1
-
22
-
-
0029965292
-
Structural features of the central cannabinoid CB1 receptor involved in the binding of the specific CB1 antagonist SR 141716A
-
Shire D, Calandra B, Delpech M, Dumont X, Kaghad M, Fur GL, Caput D and Ferrara P (1996) Structural features of the central cannabinoid CB1 receptor involved in the binding of the specific CB1 antagonist SR 141716A. J Biol Chem 271:6941-6946.
-
(1996)
J Biol Chem
, vol.271
, pp. 6941-6946
-
-
Shire, D.1
Calandra, B.2
Delpech, M.3
Dumont, X.4
Kaghad, M.5
Fur, G.L.6
Caput, D.7
Ferrara, P.8
-
23
-
-
0030425575
-
Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
-
Showalter VM, Compton DR, Martin BR and Abood ME (1996) Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands. J Pharmacol Exp Ther 278:989-999.
-
(1996)
J Pharmacol Exp Ther
, vol.278
, pp. 989-999
-
-
Showalter, V.M.1
Compton, D.R.2
Martin, B.R.3
Abood, M.E.4
-
24
-
-
0029128197
-
Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase
-
Slipetz DM, O'Neill GP, Favreau L, Dufresne C, Gallant M, Gareau Y, Guay D, Labelle M and Metters KM (1995) Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase. Mol Pharmacol 48:352-361.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 352-361
-
-
Slipetz, D.M.1
O'Neill, G.P.2
Favreau, L.3
Dufresne, C.4
Gallant, M.5
Gareau, Y.6
Guay, D.7
Labelle, M.8
Metters, K.M.9
-
25
-
-
0029866824
-
A lysine residue of the cannabinoid receptor is critical for receptor recognition by several agonists but not WIN55212-2
-
Song Z-H and Bonner TI (1996) A lysine residue of the cannabinoid receptor is critical for receptor recognition by several agonists but not WIN55212-2. Mol Pharmacol 49:891-896.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 891-896
-
-
Song, Z.-H.1
Bonner, T.I.2
-
27
-
-
0029015380
-
Classical/non-classical cannabinoid hybrids; stereochemical requirements for the southern hydroxyalkyl chain
-
Tius M, Hill W, Zou X, Busch-Petersen J, Kawakami J, Fernandez-Garcia M, Drake D, Abadji V and Makriyannis A (1995) Classical/non-classical cannabinoid hybrids; stereochemical requirements for the southern hydroxyalkyl chain. Life Sci 66:2007-2012.
-
(1995)
Life Sci
, vol.66
, pp. 2007-2012
-
-
Tius, M.1
Hill, W.2
Zou, X.3
Busch-Petersen, J.4
Kawakami, J.5
Fernandez-Garcia, M.6
Drake, D.7
Abadji, V.8
Makriyannis, A.9
-
28
-
-
0030775615
-
Arrangement of rhodopsin transmembrane alpha-helices
-
Unger V, Hargrave P, Baldwin J and Schertler G (1997) Arrangement of rhodopsin transmembrane alpha-helices. Nature 389:203-206.
-
(1997)
Nature
, vol.389
, pp. 203-206
-
-
Unger, V.1
Hargrave, P.2
Baldwin, J.3
Schertler, G.4
-
29
-
-
15844374570
-
The comformational properties of the highly selective cannabinoid receptor ligand CP-55,940
-
Xie XQ, Melvin LS and Makryiannis A (1996) The comformational properties of the highly selective cannabinoid receptor ligand CP-55,940. J Biol Chem 271:10640-10647.
-
(1996)
J Biol Chem
, vol.271
, pp. 10640-10647
-
-
Xie, X.Q.1
Melvin, L.S.2
Makryiannis, A.3
|