Assays to predict the genotoxicity of the chromosomal mutagen etoposide - Focussing on the best assay

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 493, Issue 1-2, 2001, Pages 139-147

  Turner, S D ^a,d   Wijnhoven, S W P ^b   Tinwell, H ^c   Lashford, L S ^a   Rafferty, J A ^a   Ashby, J ^c   Vrieling, H ^b   Fairbairn, L J ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ASTRAZENECA   (United Kingdom)

^d BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

APRT; Etoposide; Genotoxicity assays

Indexed keywords

CLASTOGEN; ETOPOSIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CHROMOSOME ABERRATION; CHROMOSOME MUTATION; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; GENE LOCUS; GENOTOXICITY; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MONONUCLEAR CELL; MOUSE; MUTATION RATE; NONHUMAN; PREDICTION; PRIORITY JOURNAL;

ADENINE PHOSPHORIBOSYLTRANSFERASE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; COMET ASSAY; DNA TOPOISOMERASES, TYPE II; ETOPOSIDE; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MICE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS; SPLEEN;

MURINAE;

EID: 0035958287     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(01)00170-X     Document Type: Article

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