A comparison of intraperitoneal and oral gavage administration in comet assay in mouse eight organs

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 493, Issue 1-2, 2001, Pages 39-54

  Sekihashi, Kaoru ^a,b   Sasaki, Takuro ^a   Yamamoto, Ayumu ^a   Kawamura, Kohtaro ^b   Ikka, Tsuguo ^b   Tsuda, Shuji ^c   Sasaki, Yu F ^a  

^a HACHINOHE NATIONAL COLLEGE OF TECHNOLOGY   (Japan)

^b Safety Research Institute for Chemical Compounds Co Ltd   (Japan)

^c IWATE UNIVERSITY   (Japan)

Author keywords

Alkaline single cell gel electrophoresis (SCG) assay; Comet assay; Mouse multiple organs; Route of administration

Indexed keywords

ALKYLATING AGENT; AROMATIC AMINE; AROMATIC HYDROCARBON; AZO COMPOUND; AZO DYE; AZO REDUCTASE; HYDRAZINE DERIVATIVE; INORGANIC SALT; MESYLIC ACID METHYL ESTER; MUTAGENIC AGENT; PROMUTAGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER; BONE MARROW; BRAIN; COLON; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; ENZYME ACTIVATION; ENZYME SYNTHESIS; GASTROINTESTINAL MUCOSA; GASTROINTESTINAL TRACT; GENOTOXICITY; KIDNEY; LD 50; LIVER; LUNG; MALE; MICROFLORA; MOUSE; MUTAGEN TESTING; NONHUMAN; PRIORITY JOURNAL; SAMPLING; STOMACH;

ADMINISTRATION, ORAL; ALKYLATING AGENTS; AMINES; ANIMALS; AZO COMPOUNDS; COMET ASSAY; DIGESTIVE SYSTEM; DNA DAMAGE; HYDRAZINES; HYDROCARBONS, AROMATIC; INJECTIONS, INTRAPERITONEAL; LIVER; MALE; MICE; MUTAGENS; ORGAN SPECIFICITY; SALTS;

EID: 0035958282     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(01)00157-7     Document Type: Article

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