Structural Plasticity of an Invariant Hydrophobic Triad in the Switch Regions of Rab GTPases Is a Determinant of Effector Recognition

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13982-13988

  Merithew, Eric ^b   Hatherly, Scott ^b   Dumas, John J ^b   Lawe, Deirdre C ^b   Heller Harrison, Robin ^b   Lambright, David G ^a  

^a Program in Molecular Medicine   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CRYSTAL STRUCTURE; HYDROPHOBICITY; NUCLEIC ACIDS; PLASTICITY;

CONFORMATIONAL SWITCH REGIONS;

ENZYMES;

GUANOSINE TRIPHOSPHATASE; RAB PROTEIN; EPITOPE; NERVE PROTEIN; PHENYLALANINE; RAB5C PROTEIN, HUMAN; RABPHILIN 3A; RABPHILIN-3A; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRYPTOPHAN; TYROSINE; VESICULAR TRANSPORT PROTEIN;

ARTICLE; CRYSTALLOGRAPHY; ENDOCYTOSIS; ENZYME PURIFICATION; ENZYME STRUCTURE; ESCHERICHIA COLI; EXOCYTOSIS; GENE EXPRESSION; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; BASE SEQUENCE; CRYSTALLOGRAPHY, X-RAY; EPITOPES; ESCHERICHIA COLI; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PHENYLALANINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RAB GTP-BINDING PROTEINS; RAB3A GTP-BINDING PROTEIN; RAB5 GTP-BINDING PROTEINS; TRYPTOPHAN; TYROSINE; VESICULAR TRANSPORT PROTEINS;

EID: 0035958009     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009771200     Document Type: Article

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