Identification of residues in the adult nicotinic acetylcholine receptor that confer selectivity for curariform antagonists

Journal of Biological Chemistry

Volumn 272, Issue 49, 1997, Pages 30793-30798

  Bren, Nina ^a   Sine, Steven M ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ALPHA BUNGAROTOXIN; ASPARTIC ACID; DIMETHYLTUBOCURARINE; HISTIDINE; ISOLEUCINE; LYSINE; NEUROMUSCULAR BLOCKING AGENT; NICOTINIC RECEPTOR; SERINE; THREONINE; TYROSINE; VALINE;

ADULT; ARTICLE; CHOLINERGIC STIMULATION; DRUG SELECTIVITY; FETUS; HUMAN; HUMAN CELL; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY;

ADULT; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NICOTINIC ANTAGONISTS; POINT MUTATION; PROTEIN CONFORMATION; RECEPTORS, NICOTINIC; RECOMBINANT FUSION PROTEINS; TUBOCURARINE;

EID: 0030692790     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.49.30793     Document Type: Article

References (20)

1. Sine, S. M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 9436-9440
2. Mishina, M., Takai, T., Imoto, K., Noda, M., Takahashi, T., Numa, S., Methfessel, C., and Sakmann, B. (1986) Nature 321, 406-411
3. Neubig, R. R. and Cohen, J. B., (1979) Biochemistry 18, 5464-5475
4. Sine, S. M., and Taylor, P. (1981) J. Biol. Chem. 256, 6692-6699
5. Blount, P., and Merlie, J. P. (1989) Neuron 3, 349-357
6. Pedersen, S. E., and Cohen, J. B. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 2785-2789
7. Blount, P., and Merlie, J. P. (1991) J. Biol. Chem. 266, 14692-14696
8. Sine, S. M., and Claudio, T. (1991) J. Biol. Chem. 266, 19369-19377
9. Fu, D.-X., and Sine, S. M. (1994) J. Biol. Chem. 269, 26152-26157
10. Gardner, P. (1990) Nucleic Acids Res. 18, 6714
11. Sine, S., and Taylor, P. (1979) J. Biol. Chem. 254, 3315-3325
12. Prince, R. J., and Sine, S. M. (1996) J. Biol. Chem. 271, 25770-25777
13. Chiara, D. C., and Cohen, J. B. (1992) Biophys. J. 61, A106 (abstr.)
14. O'Leary, M. E., Filatov, G. N., and White, M. M. (1994) Am. J. Physiol. 266, C648-C653
15. Corringer, P. J., Galzi, J. L., Eisele, J. L., Bertrand, S., Changeux, J.-P., and Bertrand, D. (1995) J. Biol. Chem. 270, 11749-11752
16. Harvey, S. C., and Leutje, C. W. (1996) J. Neurosci. 16, 3798-3806
17. Sine, S. M., Kreienkamp, H.-J., Bren, N., Maeda, R., and Taylor, P. (1995) Neuron 15, 205-211
18. Sine, S. M., Quiram, P., Papanikolaou, F., Kreienkamp, H.-J., and Taylor, (1994) J. Biol. Chem. 269, 8808-8816
19. Sine, S. M. (1997) J. Biol. Chem. 272, 23521-23527
20. Tsigelny, I., Sugiyama, N., Sine, S., and Taylor, P. (1997) Biophys. J. 73, 52-66