Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3

Gene

Volumn 273, Issue 1, 2001, Pages 29-39

  Simpson, Anisha ^a   Uitto, Jouni ^a   Rodeck, Ulrich ^a   Mahoney, Mỹ G ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Fyn; Grb2; Nucleosome remodeling histone deacetylase complex; Src homology 3 binding domain

Indexed keywords

ADAPTOR PROTEIN; GREEN FLUORESCENT PROTEIN; GROWTH FACTOR RECEPTOR BINDING PROTEIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; LIGAND; MESSENGER RNA; METASTASIS ASSOCIATED PROTEIN 1; METASTASIS ASSOCIATED PROTEIN 3; PROTEIN; PROTEIN KINASE FYN; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA LIBRARY; GENE DELETION; HUMAN; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; CELL NUCLEUS; CLONING, MOLECULAR; CYTOPLASM; HISTONE DEACETYLASES; HUMANS; KERATINOCYTES; MICE; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; NUCLEAR LOCALIZATION SIGNALS; PROTEINS; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY; SRC HOMOLOGY DOMAINS; TRANSFECTION;

EID: 0035948612     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(01)00563-7     Document Type: Article

References (34)

1. Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase
2. Histone acetylation and cancer
3. Fyn tyrosine kinase is involved in keratinocyte differentiation control
4. The Grb2 adaptor
5. Inverse single-strand RACE: An adapter-independent method of 5′ RACE
6. Molecular cloning, mapping, and characterization of a novel human gene, MTA1-L1, showing homology to a metastasis-associated gene, MTA1
7. Synthetic peptides as nuclear localization signals
8. EGL-27 is similar to a metastasis-associated factor and controls cell polarity and cell migration in C. elegans
9. Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo
10. A novel zymogen granule protein (ZG29p) and the nuclear protein MTA1p are differentially expressed by alternative transcription initiation in pancreatic acinar cells of the rat
11. Role of histones acetyltransferases and deacetylases in gene regulation
12. Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal
13. The Nck SH2/SH3 adaptor protein is present in the nucleus and associates with the nuclear protein SAM68
14. Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3
15. The members of the plakin family of proteins recognized by paraneoplastic pemphigus antibodies include periplakin
16. A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs
17. Tumor metastasis-associated human MTA1 gene: Its deduced protein sequence, localization, and association with breast cancer cell proliferation using antisense phosphorothioate oligonucleotides
18. Genetics of src: Structure and functional organization of a protein tyrosine kinase
19. cDNA cloning of a novel, developmentally regulated immediate early gene activated by fibroblast growth factor and encoding a nuclear protein
20. Candidate metastasis-associated genes of the rat 13762NF mammary adenocarcinoma
21. Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase
22. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
23. Grb2 and its apoptotic isoform Grb3-3 associate with heterogeneous nuclear ribonucleoprotein C, and these interactions are modulated by poly (U) RNA
24. The Caenorhabditis elegans genes egl-27 and egr-1 are similar to MTA1, a member of a chromatin regulatory complex, and are redundantly required for embryonic patterning
25. A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines
26. Analysis of the complete sequence of the novel metastasis-associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines
27. Overexpression of the MTA1 gene in gastrointestinal carcinomas: Correlation with invasion and metastasis
28. Overexpression of metastasis-associated MTA1 mRNA in invasive oesophageal carcinomas
29. Molecular analysis of a candidate metastasis-associated gene, MTA1: Possible interaction with histone deacetylase 1
30. Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex
31. Grb2 overexpression in nuclei and cytoplasm of human breast cells: A histochemical and biochemical study of normal and neoplastic mammary tissue specimens
32. NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
33. The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities
34. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation