Tumor metastasis-associated human MTA1 gene: Its deduced protein sequence, localization, and association with breast cancer cell proliferation using antisense phosphorothioate oligonucleotides

Journal of Cellular Biochemistry

Volumn 79, Issue 2, 2000, Pages 202-212

  Nawa, Akihiro ^a   Nishimori, Katsuhiko ^b   Lin, Paul ^a   Maki, Yoshiyuki ^c   Moue, Kennsuke ^b   Sawada, Hidetomo ^d   Toh, Yasushi ^e   Fumitaka, Kikkawa ^d   Nicolson, Garth L ^f  

^a UNIVERSITY OF TEXAS   (United States)

^b TOHOKU UNIVERSITY   (Japan)

^c Science Tanaka Co Ltd   (Japan)

^d NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

^f INSTITUTE FOR MOLECULAR MEDICINE   (United States)

Author keywords

Antisense oligonucleotides; Cancer cells; Cell proliferation; Gene expression; Gene structure; Nuclear regulatory protein; Nucleosome remodeling histone deacetylase complex

Indexed keywords

AMINO ACID; ANTISENSE OLIGONUCLEOTIDE; ANTISENSE PHOSPHOROTHIOATE OLIGONUCLEOTIDE; COMPLEMENTARY DNA; HISTONE DEACETYLASE; METASTASIS ASSOCIATED GENE 1; PROTEIN; PROTEIN MTA 1; REGULATOR PROTEIN; RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL; CARCINOGENESIS; CELL GROWTH; CELL PROLIFERATION; DNA DETERMINATION; DNA LIBRARY; GENE LOCATION; GENE OVEREXPRESSION; GENE SEQUENCE; GENE STRUCTURE; HUMAN; HUMAN CELL; METASTASIS; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RNA ANALYSIS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; BREAST NEOPLASMS; CELL DIVISION; DNA, COMPLEMENTARY; EVOLUTION, MOLECULAR; HUMAN; MOLECULAR SEQUENCE DATA; NEOPLASM METASTASIS; OLIGONUCLEOTIDES, ANTISENSE; ORGANOTHIOPHOSPHORUS COMPOUNDS; PROTEINS; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS; HISTONE DEACETYLASES; HUMANS; REPRESSOR PROTEINS;

ANIMALIA; MAMMALIA;

EID: 0033795072     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4644(20001101)79:2<202::AID-JCB40>3.0.CO;2-L     Document Type: Article

References (36)

1. Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides
2. A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas
3. The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML
4. Retinoblastoma protein recruits histone deacetylase to repress transcription
5. Purification and some properties of a lung-derived growth factor that differentially stimulates the growth of tumor cells metastatic to the lung
6. Transcriptional down-regulation of a rat gene, WDNM2, in metastatic DMBA-8 cells
7. Differential expression of a novel gene, WDNM1, in nonmetastatic rat mammary adenocarcinoma cells
8. KAI1, a metastasis suppressor gene for prostate cancer of human chromosome 11p11.2
9. 2+ binding protein
10. nit-2, the major positive-acting nitrogen regulatory gene of Neurospora crassa, encodes a sequence-specific DNA-binding protein
11. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
12. Antisense inhibition of the p65 subunit of NF-κB blocks tumorigenicity and causes tumor regression
13. The regulatory gene area mediating nitrogen metabolite repression in Aspergillus nidulans. Mutations affecting specificity of gene activation alter a loop residue of a putative zinc finger
14. Rb interacts with histone deacetylase to repress transcription
15. Retinoblastoma protein represses transcription by recruiting a histone deacetylase
16. Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf
17. Sequence and expression of GLN3, a positive nitrogen regulatory gene of Saccharomyces cerevisiae encoding a protein with a putative zinc finger DNA-binding domain
18. Breast cancer metastasis-associated genes: Prognostic significance and therapeutic implications
19. Candidate metastasis-associated genes of the rat 13762NF mammary adenocarcinoma
20. Isolation of gene associated with high metastatic potential in rat mammary adenocarcinoma
21. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice
22. Identification of a ten-amino acid proline-rich SH3 binding site
23. Evidence for a novel gene associated with low tumor metastatic potential
24. Does antisense exist?
25. SPXX, a frequent sequence motif in gene regulatory proteins
26. Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members
27. Decreased expression of BRCA1 accerates growth and is often present during sporadic breast cancer progression
28. A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines
29. Analysis of the complete sequence of the novel gene mta1 differentially expressed in highly metastatic mammary adenocarcinoma and breast cancer cell lines and clones
30. Molecular analysis of a candidate metastasis-associated gene MTA1: Interaction with histone deacetylase 1
31. Scissors-grip model for DNA recognition by a family of leucine zipper proteins
32. NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
33. Effect of sequence of thioated oligonucleotides on cultured human mammary epithelial cells
34. Reversible arrest of proliferation of rat 3Y1 fibroblasts in both the G1 and G2 phases by trichostatin A
35. Structual basis for the binding of proline-rich peptides to SH3 domains
36. The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities