Identification of peptides inhibitory to recombinant cysteine proteinase, CPB, of Leishmania mexicana

Molecular and Biochemical Parasitology

Volumn 114, Issue 1, 2001, Pages 81-88

  Alves, Lira C ^a   St Hilaire, Phaedria M ^b   Meldal, Morten ^b   Sanderson, Sanya J ^c   Mottram, Jeremy C ^c   Coombs, Graham H ^c   Juliano, Luiz ^a   Juliano, Maria A ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b CARLSBERG LABORATORY   (Denmark)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Cathepsin L; Cruzain; Cysteine proteinase; Inhibitors; Leishmania; Thiol protease

Indexed keywords

ANTHRANILIC ACID; ANTIPARASITIC AGENT; CATHEPSIN L; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG DESIGN; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; HYDROLYSIS; LEISHMANIA MEXICANA; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; CATHEPSINS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; HUMANS; KINETICS; LEISHMANIA MEXICANA; MAMMALS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 0035946413     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00239-0     Document Type: Article

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