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Volumn 473, Issue 1, 2001, Pages 23-36

Loss of heterozygosity in somatic cells of the mouse: An important step in cancer initiation?

Author keywords

Aprt; Carcinogens; Loss of heterozygosity (LOH); Mutagenesis; Transgenic mouse models

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AUTOSOME; CARCINOGENESIS; CELL VIABILITY; FAMILIAL CANCER; GENE LOCUS; HETEROZYGOSITY LOSS; MARKER GENE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SOMATIC CELL; SOMATIC CELL GENETICS; TUMOR SUPPRESSOR GENE;

EID: 0035945687     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(00)00163-9     Document Type: Article
Times cited : (34)

References (57)
  • 3
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 6
    • 0025964190 scopus 로고
    • Diagnosis of heterozygous states for adenine phosphoribosyltransferase deficiency based on detection of in vivo somatic mutants in blood T-cells: Application to screening of heterozygotes
    • (1991) Am. J. Hum. Genet. , vol.48 , pp. 552-562
    • Hakoda, M.1    Yamanaka, H.2    Kamatani, N.3
  • 11
    • 0024493729 scopus 로고
    • A comparison of mutation induction at the Tk and Hprt loci in human lymphoblastoid cells: Quantitative differences are due to an additional class of mutations at the autosomal tk locus
    • (1989) Mutat. Res. , vol.216 , pp. 9-17
    • Liber, H.L.1    Yandell, D.W.2    Little, J.B.3
  • 30
    • 0034738030 scopus 로고    scopus 로고
    • Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage, Version 4
    • (2000) Mutat. Res. , vol.459 , pp. 243-274
    • Friedberg, E.C.1    Meira, L.B.2
  • 38
    • 0027340278 scopus 로고
    • 6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: New insights gained from studies of genetically engineered mammalian cell lines
    • (1993) Environ. Mol. Mutagen. , vol.22 , pp. 283-292
    • Kaina, B.1    Fritz, G.2    Coquerelle, T.3
  • 42
    • 0018356390 scopus 로고
    • The realtion between reaction kinetics and mutagenic action of mono-functional alkylating agents in higher eukaryotic systems. I. Recessive lethal mutations and translocations in Drosophila
    • (1979) Mutat. Res. , vol.62 , pp. 51-100
    • Vogel, E.1    Natarajan, A.T.2
  • 46
    • 0028122271 scopus 로고
    • International commission for protection against environmental mutagens and carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents
    • (1994) Mutat. Res. , vol.309 , pp. 109-142
    • Anderson, R.D.1    Berger, N.A.2
  • 51
    • 0002698563 scopus 로고    scopus 로고
    • LOH and mitotic recombination
    • M. Ehrlich (Ed.), DNA Alterations and Cancer, Eaton Publishing, Natick, MA
    • (2000) , pp. 191-209
    • Jasin, M.1
  • 52
    • 0034600975 scopus 로고    scopus 로고
    • Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
    • (2000) EMBO J. , vol.19 , pp. 3398-3407
    • Johnson, R.D.1    Jasin, M.2
  • 53
    • 0016851023 scopus 로고
    • Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange
    • (1975) Nature , vol.258 , pp. 121-125
    • Perry, P.1    Evans, H.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.