Valproic acid-induced changes in gene expression during neurulation in a mouse model

Teratology

Volumn 54, Issue 6, 1996, Pages 284-297

  Wlodarczyk, Bogdan C ^a,b   Craig, Johanna C ^b   Bennett, Gregory D ^b   Calvin, James A ^c   Finnell, Richard H ^b  

^a NATIONAL VETERINARY RESEARCH INSTITUTE   (Poland)

^b TEXAS A AND M UNIVERSITY   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN BCL 2; PROTEIN P53; TERATOGENIC AGENT; TRANSCRIPTION FACTOR; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CONTROLLED STUDY; EMBRYO; FEMALE; GENE EXPRESSION; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NEURAL TUBE DEFECT; NEURULATION; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; TERATOGENESIS; TUMOR SUPPRESSOR GENE;

ANIMALIA;

EID: 0030434075     PISSN: 00403709     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9926(199612)54:6<284::AID-TERA3>3.0.CO;2-Z     Document Type: Article

References (54)

1. Ardinger, H.H., J.F. Atkin, R.D. Blackston, L.J. Elsas, S.K. Clarren, S. Livingstone, D.B. Flannery, J.M. Pellock, M.J. Harrod, and E.J. Lammer (1988) Verification of the fetal valproate syndrome phenotype. Am. J. Med. Genet., 29:171-185.
2. Angel, P., K. Hattori, T. Smeal, and M. Karin (1988) The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. Cell, 55:875-885.
3. Bohmann, D., T.J. Bos, A. Admon, T. Nishimura, and P.K. Vogt (1987) Human proto-oneogene encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science, 238:1386-1392.
4. Breier, G., G.R. Dressier, and P. Gruss (1988) Primary structure and developmental expression pattern of Hox 3.1, a member of the murine Hox 3 homeobox gene cluster. EMBO J., 7:1329-1336.
5. Cole, W.A., and D.G. Trasler (1980) Gene-teratogen interaction in insulin induced mouse exencephally. Teratology, 22:125-139.
6. Danielson, P.E., S. Forss-Petter, M.A. Brow, et al. (1988) p1B15: A cDNA clone of the rat mRNA encoding cyclophilin. DNA, 7:261-267.
7. Davey, S., and D. Beach (1995) RACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutation. Mol. Biol. Cell, 6:1411-1421.
8. DiLiberti, J.H., P.A. Farndon, N.R. Dennis, and C.J.R. Curry (1984) The fetal valproate syndrome. Am. J. Med. Genet., 19:473-481.
9. Eberwine, J.H., H. Yeh, K. Miyashiro, Y. Cao, S. Nair, R.H. Finnell, M. Zeittel, and P. Coleman (1992a) Analysis of gene expression in single live neurons. Proc. Natl. Acad. Sci. U.S.A., 89:3010-3014.
10. Eberwine, J.H., C.M. Spencer, K. Miyashiro, S.A. Mackler, and R.H. Finnell (1992b) cDNA synthesis in situ: Methods and applications. Methods Enzymol., 216:80-100.
11. Ehlers, K., H. Sturje, H. Merker, and H. Nau (1992a) Valproic acid-induced spina bifida: A mouse model. Teratology, 45:145-154.
12. Ehlers, K., H. Sturje, H. Merker, and H. Nau (1992b) Spina bifida aperta induced by valproic acid and by all-trans-retinoic acid in the mouse: Distinct differences in morphology and periods of sensitivity. Teratology, 46:117-130.
13. Ellege, R.M., and W.H. Lee (1995) Life and death. Bioessays, 17:923-930.
14. Finnell, R.H. (1991) Genetic differences in susceptibility to anticonvulsant drug-induced developmental defects. Pharmacol. Toxicol., 69: 223-227.
15. Finnell, R.H., S.P. Moon, L.C. Abbott, J.A. Golden, and G.F. Chernoff (1986) Strain differences in heat induced neural tube defects in mice. Teratology, 33:247-252.
16. Finnell, R.H., G.D. Bennett, S.B. Karras, and V.K. Mohl (1988) Common hierarchies of susceptibility to the induction of neural tube defects by valproic acid and its 4-propyl-4-pentenoic acid metabolite. Teratology, 38:313-320.
17. Geelen, J.G., and J. Langman (1977) Closure of the neural tube in the cephalic region of the mouse embryo. Anat. Rec., 189:625-640.
18. Golden, J.A., and G.F. Chernoff (1993) Intermittent pattern of neural tube closure in two strains of mice. Teratology, 47:73-80.
19. Goulding, M.D., G. Chalepakis, U. Deutsch, J.R. Erselius, and P. Gruss (1991) Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBOJ., J., 10:1135-1147.
20. Hockenberry DM (1995) bcl-2, a novel regulator of cell death. Bioessays, J 7:631-638.
21. Igarashi, M., A. Nagata S. Jinno, K. Suto, and H. Okayama (1991) Wee1+-like gene in human cells. Nature, 353:80-83.
22. Johnson, R.A., and D.W. Wichern (1992) In: Applied Multivariate Statistical Analysis. S.R. Conmy, eds. Prentice-Hall, Englewood Cliffs, NJ, pp. 356-395.
23. Kaufman, M.H. (1979) Cephalic neurulation and optic vessel formation in the early mouse embryo. Am. J. Anat., 155:425-444.
24. 1 transition of mouse fibroblasts: in vitro and in vivo associations. Mol. Cell. Biol., 11:2451-2459.
25. Lammer, E.J., L.E. Sever, and G.P. Oakley, Jr. (1987) Teratogen update: Valproic acid. Teratology, 35:465-473.
26. Lindhout, D., H. Meinardi, J.W.A. Meijer, and H. Nau (1992) Antiepileptic drugs and teratogenesis in two consecutive cohorts: Changes in prescription policy paralleled by changes in pattern of malformations. Neurology, 42:94-110.
27. Macdonald, K.B., D.M. Juriloff, and M.J. Harris (1989) Developmental study of neural tube closure in a mouse stock with high incidence of exencephaly. Teratology, 35:195-213.
28. Mason, R.L., R.F. Gunst, and J.L. Hess (1989) Statistical Design and Analysis of Experiments. New York: John Wiley and Sons.
29. Miyashita, T., S. Krajewski, M. Krajewska, H.G. Wang, H.K. Lin, D.A. Liebermann, B. Hoffman, and J.C. Reed (1994) Tumor supressor p53 is a regulator of Bcl-2 and bax gene expression in vitro and in vivo. Oncogene, 9:1799-1805.
30. Nau, H. (1985) Teratogenic valproic acid concentrations: Infusion by implanted mimpumps vs conventional regimen in the mouse. Toxicol Appl Pharmacol., 80:243-250.
31. Nau, H., and W.J. Scott (1986) Weak acids may act as teratogens by accumulating in the basic milieu of the early mammalian embryo. Nature, 323:276-278.
32. i in the embryo during organogenesis and structure-activity considerations. Arch. Toxicol., 11:128-139.
33. Neter, J., W. Wasserman, and M.H. Kutner (1989) Linear regression with one independent variable. In: Applied Linear Regression Models. R.D. Irwin, eds. Irwin, Boston, pp. 10-40.
34. Niedermeyer, E. (1983) Epilepsy Guide: Diagnosis and Treatment of Epileptic Seizure Disorders. Urban and Schwarzenberg, Baltimore, p. 173.
35. Prakash, M., and M.N. Murty (1995) A genetic approach for selection of (Near-) Optimal subsets of principal components of discrimination. Pattern Recog. Lett., 16:781-787.
36. Ptashne, M. (1988) How eukaryotic transcriptional activators work. Nature, 335:683-689.
37. Rao, C.R. (1973) Linear Statistical Inference and Its Applications. 2nd Ed. John Wiley & Sons, New York, pp. 78-147.
38. Robert, E. (1982) Valproic acid and spina bifida: A preliminary report-France. CDC M.M.W.R. 31:565-566.
39. Robert, E., and P. Guibaud P (1982) Maternal valproic acid and congenital neural tube defects. Lancet, 2:937.
40. Rohlf, J.F., and F.L. Bookstein (1990) Traditional Morphometrics. In: Proceedings of the Michigan Morphometrics Workshop. J.F. Rohlf, and F.L. Bookstein, eds. University of Michigan Museum of Zoology, Ann Arbor, pp. 77-125.
41. Ryseck, R.P, and Bravo, R. (1991) C-Jun, Jun-b and Jun-d differ in their binding affinities to AP-1 and cre consensus sequences; effect of Fos proteins. Oncogene, 6:533-542.
42. Sah, V.P., L.D. Attardi, G.J. Mulligan, B.O. Williams, R.T. Bronson, and T.A. Jacks (1995) Subset of p53-deficient embryos exhibit exencephaly. Nature Genet., 10:175-180.
43. SAS Institute (1990) in SAS/STAT User's Guide Release 6.03. SAS Institute, Cary, NC, pp. 677-771, 891-996, 1241-1263.
44. Simeone, A., D. Acampora, M. Gulisano, A. Stornaiuolo, and E. Bondnelli (1992) Nested expression domains of four homeobox genes in developing rostral brain. Nature, 358:687-690.
45. Snell, G.D., E. Fekete, and K.P. Hummel (1948) The relation of mating, ovulation, and the estrus smear in the house mouse to the time of day. Anat. Rec., 76:30-54.
46. Sokal, R.R., and F.J. Rohlf (1981) Biometry. 2nd Ed. W.H. Freeman, San Francisco.
47. Taylor, L.E., G.D. Bennett, and R.H. Finnell (1995) Altered gene expression in murine branchial arches following in utero exposure to retinoic acid. J. Cranio. Genet. Dev. Biol., 75:13-25.
48. Veis-Novack, D., and S.J. Korsmeyer (1994) Bcl-2 protein expression during murine development. Am. J. Pathol., 145:61-73.
49. Wang, Y., L. Szekely, I. Okan, G. Klein, and K.G. Wiman (1993) Wild-type p53-triggered apoptosis is inhibited by Bcl-2 in a v-mycinduced T-cell lymphoma line. Oncogene, 8:3427-3431.
50. Wegner, C., and H. Nau (1991) Diurnal variation of folate concentrations in mouse embryo and plasma: The protective effect of folinic acid on valproic acid-induced teratogenicity is time-dependent. Reprod. Toxicol., 5:465-471.
51. Weinberg, R.A. (1985) The action of oncogenes in the cytoplasm and nucleus. Science, 230:770-778.
52. Wegner, C., and H. Nau (1992) Alteration of embryonic folate metabolism by valproic acid during organogenesis: Implications for mechanism of teratogenesis. Neurology, 42:17-24.
53. Wilson, J.G. (1977) Current status of teratology. In: Handbook of Teratology: General Principles and Etiology. J.G. Wilson, and F.C. Fraser, eds. Plenum Press, New York, pp. 47-74.
54. Wlodarczyk, B., G.D. Bennett, J.A. Calvin, and R.H. Finnell (1996) Arsenic induced changes in transcription factor gene expression: Implications for abnormal neural development. Dev. Genet., 18:306-315.