Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5′-phosphate and L-histidinol phosphate

Journal of Molecular Biology

Volumn 311, Issue 4, 2001, Pages 761-776

  Sivaraman, J ^a,b   Li, Yunge ^a,b   Larocque, Robert ^a,b   Schrag, Joseph D ^a,b   Cygler, Miroslaw ^a,b   Matte, Allan ^a,b  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b Montreal Joint Centre for Structural Biology   (Canada)

Author keywords

Gem diamine; Histidinol phosphate aminotransferase; Pyridoxal 5 phosphate

Indexed keywords

AMINOTRANSFERASE; HISTIDINOLPHOSPHATE AMINOTRANSFERASE; PYRIDOXAL 5 PHOSPHATE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMICAL REACTION; COMPLEX FORMATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DIMERIZATION; ENZYME ANALYSIS; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; ZYMOMONAS MOBILIS;

EID: 0035943396     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4882     Document Type: Article

References (56)

1. Biosynthesis of histidine
2. Molecular evolution of the histidine biosynthetic pathway
3. The molecular evolution of pyridoxal-5′-phosphate dependent enzymes
4. Histidine biosynthetic pathway and genes: Structure, regulation and evolution
5. Imidazole glycerol phosphate synthase: The glutamine amidotransferase in histidine biosynthesis
6. Structural evidence for evolution of the β/α barrel scaffold by gene duplication
7. Evolutionary recruitment of biochemically specialized subdivisions of family I within the protein superfamily of aminotransferases
8. Evolutionary relationships among aminotransferases. Tyrosine aminotransferase, histidinol-phosphate aminotransferase and aspartate aminotransferase are homologous proteins
9. L-histidinol phosphate aminotransferase from Salmonella typhimurium. Kinetic behavior and sequence at the pyridoxal-P binding site
10. Cloning, structure and expression of the Escherichia coli K12 HisC gene
11. Cloning of the his5 gene of Saccharomyces cerevisae by yeast transformation
12. Molecular cloning and expression of a cDNA sequence encoding histidinol phosphate aminotransferase from Nicotina tabacum
13. Crystalline L-histidinol phosphate aminotransferase from Salmonella typhimurium. Purification and subunit structure
14. Some comparative kinetic data on the enzyme imidazoleacetol phosphate: L-glutamate aminotransferase derived from mutant strains of Salmonella typhimurium
15. Imidazolylacetolphosphate: L-glutamate aminotransferase - Mechanism of action
16. Imidazolylacetolphosphate:L-glutamate aminotransferase. Purification and physical properties
17. Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure
18. Imidazole acetol phosphate aminotransferase in Zymomonas mobolis: Molecular genetic, biochemical and evolutionary analyses
19. Purification and properties of two aromatic aminotransferases in Bacillus subtilis
20. 6-dependent enzymes
21. Pyridoxal phosphate-dependent enzymes
22. Serine transhydroxymethylase. Relaxation and transient kinetic study of the formation and interconversion of the enzyme-glycine complexes
23. A reaction pathway for transimination of the pydridoxal 5′-phosphate in D-serine dehydratase by amino acids
24. Serine hydroxymethyltransferase: Origin of substrate specificity
25. Mechanism of action of aspartate aminotransferase proposed on the basis of its spatial structure
26. Crystal structure of rabbit cytosolic serine hydroxymethyltransferase at 2.8 Å resolution: Mechanistic implications
27. PROCHECK: A program to check the stereochemical quality of protein structures
28. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
29. Protein structure comparison by alignment of distance matrices
30. Structure of Thermus thermophilus HB8 aspartate aminotransferase and its complex with maleate
31. Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: Substrate specificity is influenced by cofactor binding
32. Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene
33. X-ray structure of MalY from Escherichia coli: A pyridoxal 5′-phosphate-dependent enzyme acting as a modulator in real gene expression
34. Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from E. coli complexed with a PLP-substrate intermediate: Inferred reaction mechanism
35. Pyridoxal enzymes: Mechanistic diversity and uniformity
36. pH Studies on the mechanism of the pyridoxal phosphate-dependent dialkylglycine decarboxylase
37. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
38. Influence of electrostatic effects on activation barriers in enzymatic reactions: Pyridoxal 5′-phosphate-dependent decarboxylation of α-amino acids
39. Serine hydroxymethyltransferase
40. Inactivation of D-serine dehydratase by alkylamines via a transimination of enzyme-linked cofactor
41. Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): A vehicle for direct determination of three-dimensional structure
42. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
43. Sparse matrix sampling: A screening method for crystallization of proteins
44. CHOOCH: A program for deriving anomalous scattering factors from X-ray fluorescence spectra
45. Processing of X-ray diffraction data collected in oscillation mode
46. Automated MAD and MIR structure solution
47. "dm": An automated procedure for phase improvement by density modification
48. The CCP4 suite: Programs for protein crystallography
49. Automated protein model building combined with iterative structure refinement
50. Improved methods for building protein models in electron density maps and the location of errors in these models
51. Crystallography and NMR system: A new software suite for macromolecular structure determination
52. The protein databank
53. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
54. Raster3D: Photo-realistic nolecular graphics
55. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
56. LIGPLOT: A program to generate schematic diagrams of protein-ligand interactions