Overexpression of human telomerase RNA is an early event in oesophageal carcinogenesis

Virchows Archiv

Volumn 434, Issue 6, 1999, Pages 483-487

  Hiyama, Toru ^a   Yokozaki, Hiroshi ^a   Kitadai, Yasuhiko ^a   Haruma, Ken ^a   Yasui, Wataru ^a   Kajiyama, Goro ^a   Tahara, Eiichi ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Human telomerase RNA; In situ mRNA hybridization; Oesophageal carcinoma; Oesophageal dysplasia

Indexed keywords

KI 67 ANTIGEN; RNA; TELOMERASE;

ARTICLE; CARCINOGENESIS; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; DYSPLASIA; ESOPHAGUS CARCINOMA; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; MAJOR CLINICAL STUDY; NORMAL HUMAN; PRIORITY JOURNAL; RNA DEGRADATION; RNA PROBE; SQUAMOUS CELL CARCINOMA;

ESOPHAGEAL NEOPLASMS; ESOPHAGUS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IN SITU HYBRIDIZATION; KI-67 ANTIGEN; RNA, MESSENGER; TELOMERASE;

EID: 0033011719     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280050372     Document Type: Article

References (37)

1. 1. Adams RR, Chang E, Allsopp RC, Yu J, Le S, West MD, Harley CB, Andrews WH, Greider CW, Villeponteau B (1995) The RNA component of human telomerase. Science 269:1236-1241
2. 2. Aoki T, Du X, Nishihara T, Matsubara T, Nakamura Y (1994) Allelotype of esophageal carcinoma. Genes Chromosom Cancer 10:177-182
3. 3. Avillion AA, Piatyszek A, Gupta J, Shay JW, Bacchetti S, Greider CW (1996) Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res 56:645-650
4. 4. Blackburn EH (1991) Structure and function of telomeres. Nature 350:569-573
5. 5. Blasco MA, Rizen M, Greider CW, Hanahan D (1996) Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis. Nat Genet 12:200-204
6. 6. Caruthers MH, Beaucage SL, Efcavitch JW, Fisher EF, Goldman RA, DeHaseth PL, Mandecki W, Matteucci MD, Rosendahl MS, Stabinsky Y (1982) Chemical synthesis and biological studies on mutated gene-control regions. Cold Spring Harbor Symp Quant Biol 47:411-418
7. 7. Counter CM, Botelho P, Wang P, Harley CB, Bacchetti S (1994) Stabilization of short telomeres and telomerase activity accompanying immortalization of Epstein-Barr virus-transformed human B lymphocytes. J Virol 68:3410-3414
8. 8. Greene GF, Kitadai Y, Pettaway CA, von Eschenbach AC, Bucna CD, Fidler IJ (1997) Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique. Am J Pathol 150: 1571-1582
9. 9. Greider CW, Blackburn EH (1985) Identification of a specific telomere terminal transferase activity in tetrahymena extracts. Cell 43:405-413
10. 10. Harley CB, Futcher AB, Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460
11. 11. Hiyama T, Yokozaki H, Kitadai Y, Tahara E, Tahara H, Ide T, Haruma K, Yasui W, Kajiyama G, Tahara E (1998) In situ mRNA hybridization technique for analysis of human telomerase RNA in gastric precancerous and cancerous lesions. Jpn J Cancer Res 89:1187-1194
12. 12. Hollstein MC, Metcalf RA, Welsh JA, Montesano R, Harris CC (1990) Frequent mutation of the p53 gene in human esophageal cancer. Proc Natl Acad Sci USA 87:9958-9961
13. 13. Japanese Society for Esophageal Diseases (1992) Guide line for the clinical and pathologic studies on carcinoma of the esophagus, 8th edn. Kanehara, Tokyo
14. 14. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PLC, Coviello GM, Wright WE, Weinrich SL, Shay JW (1994) Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011-2014
15. 15. Kitadai Y, Bucana CD, Ellis LM, Anzai H, Tahara E, Fidler IJ (1995) In situ mRNA hybridization technique for analysis of metastasis-related genes in human colon carcinoma cells. Am J Pathol 147:1238-1247
16. 16. Kitadai Y, Ellis LM, Takahashi Y, Bucana CD, Anzai H, Tahara E, Fidler IJ (1995) Multiparametric in situ messenger RNA hybridization analysis to detect metastasis-related genes in surgical specimens of human colon carcinomas. Clin Cancer Res 1:1095-1102
17. 17. Kitadai Y, Ellis LM, Tucker SL, Greene GF, Bucana CD, Cleary KR, Takahashi Y, Tahara E, Fidler IJ (1996) Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinoma. Am J Pathol 149:1541-1551
18. 18. Kitagawa Y, Ueda M, Ando N, Shinozawa Y, Shimizu N, Abe O (1991) Significance of int-2/hst-1 coamplification as a prognostic factor in patients with esophageal carcinoma. Cancer Res 51:1504-1508
19. 19. Kolquist KA, Ellisen LW, Counter CM, Meyerson M, Tan LK, Weinberg RA, Haber DA, Gerald WL (1998) Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. Nat Genet 19:182-186
20. 20. Kuniyasu H, Domen T, Hamamoto T, Yokozaki H., Yasui W, Tahara H, Tahara E (1997) Expression of human telomerase RNA is an early event of stomach carcinogenesis. Jpn J Cancer Res 88:103-107
21. 21. Meyerson M, Counter CM, Eaton EN, Ellisen LW, Steiner P, Caddle SD, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA (1997) hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 90:785-795
22. 22. Morin G B (1989) The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59:521-529
23. 23. Nakamura TM, Morin GB, Chapman KB, Weinrich SL, Andrews WH, Lingner J, Harley CB, Cech TR (1997) Telomerase catalytic subunit homologs from fission yeast and human. Science 277:955-959
24. 24. Nakayama J, Tahara H, Tahara E, Saito M, Ito K, Nakamura H, Nakanishi T, Tahara E, Ide T, Ishikawa F (1998) Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas. Nat Genet 18:65-68
25. 25. Park CS, Brigati DJ, Manahan LJ (1991) Automated molecular pathology: one hour in situ DNA hybridization. J Histotechnol 14:219-229
26. 26. Qui SL, Yang GR (1988) Precursor lesion of esophageal cancer in high-risk populations in Henan province, China. Cancer 62:551-557
27. 27. Reed JA, Manahan LJ, Park CS, Brigati DJ (1992) Complete one-hour immunocytochemistry based on capillary action. Biotechniques 13:434-443
28. 28. Sallinen P, Miettinen H, Sallinen SL, Haapasalo H, Helin H, Kononen J (1997) Increased expression of telomerase RNA component is associated with increased cell proliferation in human astrocytomas. Am J Pathol 150:1159-1164
29. 29. Shibagaki I, Shimada Y, Wagata T, Ikenaga M, Imamura M, Ishizaki K (1994) Allelotype analysis of esophageal squamous cell carcinoma. Cancer Res 54:2996-3000
30. 30. Soder AI, Hoare SF, Muir S, Going JJ, Parkinson EK, Keith WN (1997) Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer. Oncogene 14:1013-1021
31. 31. Tahara E (1996) Molecular diagnosis of gastrointestinal cancers: the application to clinical practice. Int J Clin Oncol 1:63-68
32. 32. Tahara H, Tahara E, Tahara E, Ide T (1997) Telomeres and telomerase in gastrointestinal cancers. In: Tahara E (ed) Molecular pathology of gastroenterological cancer: application to clinical practice. Springer, Tokyo, pp 245-259
33. 33. Takubo K, Nakamura K, Izumiyama N, Mafune K, Tanaka Y, Miyashita M, Sasajima K, Kato M, Oshimura M (1997) Telomerase activity in esophageal carcinoma. J Surg Oncol 66:88-92
34. 34. Yashima K, Piatyszek MA, Saboorian HM, Virmani AK, Brown D, Shay JW, Gazdar AF (1997) Telomerase activity and in situ telomerase RNA expression in malignant and nonmalignant lymph nodes. J Clin Pathol 50:110-117
35. 35. Yashima K, Litzky LA, Kaiser L, Rogers T, Lam S, Wistuba II, Milchgrub S, Srivastava S, Piatyszek MA, Shay JW, Gazdar AF (1997) Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas. Cancer Res 57:2373-2377
36. 36. Yasui W, Kuniyasu H, Yokozaki H, Semba S, Shimamoto F, Tahara E (1996) Expression of cyclin E in colorectal adenomas and adenocarcinomas: correlation with expression of Ki-67 antigen and p53 protein. Virchows Arch 429:13-19
37. 37. Yoshida K, Kawami H, Kuniyasu H, Nishiyama M, Yasui W, Hirai T, Toge T, Tahara E (1994) Coamplification of cyclin D, hst-1 and and int-2 genes is a good biological marker of high malignancy for human esophageal carcinomas. Oncol Rep 1:493-496