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Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 2, 2001, Pages 107-111

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: Structure-activity relationships of apicidin. Part 1

(16) Colletti, Steven L a Myers, Robert W a Darkin Rattray, Sandra J a Gurnett, Anne M a Dulski, Paula M a Galuska, Stefan a Allocco, John J a Ayer, Michelle B a Li, Chunshi a Lim, Julie a Crumley, Tami M a Cannova, Christine a Schmatz, Dennis M a Wyvratt, Matthew J a Fisher, Michael H a Meinke, Peter T a

a MERCK RESEARCH LABORATORIES (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTOZOAL AGENT; APICIDIN DERIVATIVE; HISTONE DEACETYLASE INHIBITOR; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME BINDING; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIPROTOZOAL AGENTS; BIOLOGICAL FACTORS; CATTLE; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; EIMERIA TENELLA; ENZYME INHIBITORS; FUSARIUM; HELA CELLS; HISTONE DEACETYLASES; HUMANS; MICROBIAL SENSITIVITY TESTS; PEPTIDES, CYCLIC; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA; PROTOZOA;

EID: 0035931503 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(00)00604-1 Document Type: Article

Times cited : (75)

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