Broad spectrum antiprotozoal agents that inhibit histone deaceltylase: Structure-activity relationships of apicidin. Part 2

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 2, 2001, Pages 113-117

  Colletti, Steven L ^a   Myers, Robert W ^a   Darkin Rattray, Sandra J ^a   Gurnett, Anne M ^a   Dulski, Paula M ^a   Galuska, Stefan ^a   Allocco, John J ^a   Ayer, Michelle B ^a   Li, Chunshi ^a   Lim, Julie ^a   Crumley, Tami M ^a   Cannova, Christine ^a   Schmatz, Dennis M ^a   Wyvratt, Matthew J ^a   Fisher, Michael H ^a   Meinke, Peter T ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTOZOAL AGENT; APICIDIN DERIVATIVE; HISTONE DEACETYLASE INHIBITOR; INDOLE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIPROTOZOAL AGENTS; BIOLOGICAL FACTORS; CATTLE; CELL DIVISION; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; EIMERIA TENELLA; ENZYME INHIBITORS; FUSARIUM; HELA CELLS; HISTONE DEACETYLASES; HUMANS; INDOLES; MICROBIAL SENSITIVITY TESTS; PEPTIDES, CYCLIC; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN;

MAMMALIA; PROTOZOA;

EID: 0035931464     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00605-3     Document Type: Article

References (6)