The Transcription Factors SOX9 and SOX10 are Vitiligo Autoantigens in Autoimmune Polyendocrine Syndrome Type I

Journal of Biological Chemistry

Volumn 276, Issue 38, 2001, Pages 35390-35395

  Hedstrand, Håkan ^a   Ekwall, Olov ^a   Olsson, Mats J ^a   Landgren, Eva ^a   Kemp, E Helen ^b   Weetman, Anthony P ^b   Perheentupa, Jaakko ^c   Husebye, Eystein ^d   Gustafsson, Jan ^a   Betterle, Corrado ^e   Kämpe, Olle ^a   Rorsman, Fredrik ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b NORTHERN GENERAL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF HELSINKI   (Finland)

^d HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^e UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; DISEASE CONTROL; DNA; PATIENT TREATMENT; TISSUE;

HEREDITARY DISORDERS; IMMUNOSCREENING;

ANTIGENS;

AUTOANTIBODY; AUTOANTIGEN; COMPLEMENT FIXING ANTIBODY; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX10; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HIGH MOBILITY GROUP PROTEIN; PRIMER DNA; RECOMBINANT PROTEIN; SOX-10 TRANSCRIPTION FACTOR; SOX-9 TRANSCRIPTION FACTOR;

ANTIBODY TITER; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY; AUTOSOMAL RECESSIVE INHERITANCE; BLOOD SAMPLING; DNA LIBRARY; GENETIC DISORDER; HAIR FOLLICLE; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; SCALP; TISSUE SPECIFICITY; VITILIGO; AUTOIMMUNE POLYENDOCRINOPATHY; FEMALE; IMMUNOLOGY; MALE; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERODIAGNOSIS; WESTERN BLOTTING;

AUTOANTIGENS; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; DNA-BINDING PROTEINS; FEMALE; HIGH MOBILITY GROUP PROTEINS; HUMANS; MALE; POLYENDOCRINOPATHIES, AUTOIMMUNE; PRECIPITIN TESTS; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; VITILIGO;

EID: 0035929680     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102391200     Document Type: Article

References (59)

1. Ahonen, P., Myllarniemi, S., Sipila, I., and Perheentupa, J. (1990) N. Engl. J. Med. 322, 1829-1836
2. The Finnish German APECED Consortium (1997) Nat. Genet. 17, 399-403
3. Nagamine, K., Peterson, P., Scott, H. S., Kudoh, J., Minoshima, S., Heino, M., Krohn, K. J., Lalioti, M. D., Mullis, P. E., Antonarakis, S. E., Kawasaki, K., Asakawa, S., Ito, F., and Shimizu, N. (1997) Nat. Genet. 17, 393-398
4. Neufeld, M., Maclaren, N., and Blizzard, R. (1980) Pediatr. Ann. 9, 154-162
5. Betterle, C., Greggio, N. A., and Volpato, M. (1998) J. Clin. Endocrinol. Metab. 83, 1049-1055
6. Chen, S., Sawicka, J., Betterle, C., Powell, M., Prentice, L., Volpato, M., Rees Smith, B., and Furmaniak, J. (1996) J. Clin. Endocrinol. Metab. 81, 1871-1876
7. Uibo, R., Aavik, E., Peterson, P., Perheentupa, J., Aranko, S., Pelkonen, R., and Krohn, K. J. (1994) J. Clin. Endocrinol. Metab. 78, 323-328
8. Winqvist, O., Söderbergh, A., and Kämpe, O. (1996) Mol. Med. Today 2, 282-289
9. Rorsman, F., Husebye, E. S., Winqvist, O., Björk, E., Karlsson, F. A., and Kämpe, O. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8626-8629
10. Tuomi, T., Björses, P., Falorni, A., Partanen, J., Perheentupa, J., Lernmark, A., and Miettinen, A. (1996) J. Clin. Endocrinol. Metab. 81, 1488-1494
11. Gebre-Medhin, G., Husebye, E. S., Gustafsson, J., Winqvist, O., Goksoyr, A., Rorsman, F., and Kämpe, O. (1997) FEBS Lett. 412, 439-445
12. Ekwall, O., Hedstrand, H., Grimelius, L., Haavik, J., Perheentupa, J., Gustafsson, J., Husebye, E., Kämpe, O., and Rorsman, F. (1998) Lancet 352, 279-283
13. Hedstrand, H., Ekwall, O., Haavik, J., Landgren, E., Betterle, C., Perheentupa, J., Gustafsson, J., Husebye, E., Rorsman, F., and Kämpe, O. (2000) Biochem. Biophys. Res. Commun. 267, 456-461
14. Mirakian, R., Locatelli, M., and Bottazzo, G. F. (1998) Lancet 352, 255-256
15. Lerner, A. B. (1971) Am. J. Med. 51, 141-147
16. Betterle, C., Caretto, A., De Zio, A., Pedini, B., Veller-Fornasa, C., Cecchetto, A., Accordi, F., and Peserico, A. (1985) Dermatologica (Basel) 171, 419-423
17. Gould, I. M., Gray, R. S., Urbaniak, S. J., Elton, R. A., and Duncan, L. J. (1985) Br. J. Dermatol. 113, 153-155
18. Cunliffe, W. J., Hall, R., Newell, D. J., and Stevenson, C. J. (1968) Br. J. Dermatol. 80, 135-139
19. Schallreuter, K. U., Lemke, R., Brandt, O., Schwartz, R., Westhofen, M., Montz, R., and Berger, J. (1994) Dermatology (Basel) 188, 269-275
20. Grunnet, I., Howitz, J., Reymann, F., and Schwartz, M. (1970) Arch. Dermatol. 101, 82-85
21. Howitz, J., and Schwartz, M. (1971) Lancet 1, 1331-1334
22. Cui, J., Harning, R., Henn, M., and Bystryn, J. C. (1992) J. Invest. Dermatol. 98, 162-165
23. Naughton, G. K., Eisinger, M., and Bystryn, J. C. (1983) J. Exp. Med. 158, 246-251
24. Kemp, E. H., Gawkrodger, D. J., Watson, P. F., and Weetman, A. P. (1998) Clin. Exp. Immunol. 114, 333-338
25. Song, Y. H., Connor, E., Li, Y., Zorovich, B., Balducci, P., and Maclaren, N. (1994) Lancet 344, 1049-1052
26. Kemp, E. H., Waterman, E. A., Gawkrodger, D. J., Watson, P. F., and Weetman, A. P. (1998) Br. J. Dermatol. 139, 798-805
27. Hertz, K. C., Gazze, L. A., Kirkpatrick, C. H., and Katz, S. I. (1977) N. Engl. J. Med. 297, 634-637
28. Betterle, C., Marakian, R., Doniach, D., Bottazzo, G. F., Riley, W., and Maclaren, N. K. (1984) Lancet 1, 159
29. Betterle, C., Caretto, A., Pedini, B., Rigon, F., Bertoli, P., and Peserico, A. (1992) Arch. Dermatol. 128, 123-124
30. Hedstrand, H., Perheentupa, J., Ekwall, O., Gustafsson, J., Michaelsson, G., Husebye, E., Rorsman, F., and Kämpe, O. (1999) J. Invest. Dermatol. 113, 1054-1058
31. Velloso, L. A., Winqvist, O., Gustafsson, J., Kämpe, O., and Karlsson, F. A. (1994) Dermatologica (Basel) 37, 61-69
32. Kuhlbrodt, K., Herbarth, B., Sock, E., Hermans-Borgmeyer, I., and Wegner, M. (1998) J. Neurosci. 18, 237-250
33. Husebye, E. S., Gebre-Medhin, G., Tuomi, T., Perheentupa, J., Landin-Olsson, M., Gustafsson, J., Rorsman, F., and Kämpe, O. (1997) J. Clin. Endocrinol. Metab. 82, 147-150
34. Olsson, M. J., and Juhlin, L. (1993) Acta Derm. Venereol. 73, 49-51
35. Olsson, M. J., Moellmann, G., Lerner, A. B., and Juhlin, L. (1994) Acta Derm. Venereol. 74, 226-228
36. Kämpe, O., Andersson, A., Björk, E., Hallberg, A., and Karlsson, F. A. (1989) Diabetes 38, 1326-1328
37. Winqvist, O., Gustafsson, J., Rorsman, F., Karlsson, F. A., and Kämpe, O. (1993) J. Clin. Invest. 92, 2377-2385
38. Foster, J. W., Dominguez-Steglich, M. A., Guioli, S., Kowk, G., Weller, P. A., Stevanovic, M., Weissenbach, J., Mansour, S., Young, I. D., and Goodfellow, P. N. (1994) Nature 372, 525-530
39. Southard-Smith, E. M., Kos, L., and Pavan, W. J. (1998) Nat. Genet. 18, 60-64
40. Grosschedl, R., Giese, K., and Pagel, J. (1994) Trends Genet. 10, 94-100
41. Wegner, M. (1999) Nucleic Acids Res. 27, 1409-1420
42. Prior, H. M., and Walter, M. A. (1996) Mol. Med. 2, 405-412
43. Bondurand, N., Kobetz, A., Pingault, V., Lemort, N., Encha-Razavi, F., Couly, G., Goerich, D. E., Wegner, M., Abitbol, M., and Goossens, M. (1998) FEBS Lett. 432, 168-172
44. Lee, M., Goodall, J., Verastegui, C., Ballotti, R., and Goding, C. R. (2000) J. Biol. Chem. 275, 37978-37983
45. Goding, C. R. (2000) Genes Dev. 14, 1712-1728
46. Pingault, V., Bondurand, N., Kuhlbrodt, K., Goerich, D. E., Prehu, M. O., Puliti, A., Herbarth, B., Hermans-Borgmeyer, I., Legius, E., Matthijs, G., Amiel, J., Lyonnet, S., Ceccherini, I., Romeo, G., Smith, J. C., Read, A. P., Wegner, M., and Goossens, M. (1998) Nat. Genet. 18, 171-173
47. Wagner, T., Wirth, J., Meyer, J., Zabel, B., Held, M., Zimmer, J., Pasantes, J., Bricarelli, F. D., Keutel, J., and Hustert, E. (1994) Cell 79, 1111-1120
48. Wang, S. J., Shohat, T., Vadheim, C., Shellow, W., Edwards, J., and Rotter, J. I. (1994) Am. J. Med. Genet. 51, 234-239
49. Tobin, D. J., and Bystryn, J. C. (1996) Pigment Cell Res. 9, 304-310
50. Galbraith, G. M., Miller, D., and Emerson, D. L. (1988) Clin. Immunol. Immunopathol. 48, 317-324
51. Muhlen, C. V., and Tan, E. (1995) Semin. Arthritis Rheum. 5, 323-358
52. Morse, J. H., Barst, R. J., Fotino, M., Zhang, Y., Flaster, E., and Fritzler, M. J. (1996) Clin. Exp. Immunol. 106, 389-395
53. Bustin, M., Reisch, J., Einck, L., and Klippel, J. H. (1982) Science 215, 1245-1247
54. Neuer, G., Bustin, M., Michels, H., Truckenbrodt, H., and Bautz, F. A. (1992) Arthritis Rheum. 35, 472-475
55. Ayer, L. M., Rubin, R. L., Dixon, G. H., and Fritzler, M. J. (1994) Arthritis Rheum. 37, 98-103
56. Kasimiotis, H., Myers, M. A., Argentaro, A., Mertin, S., Fida, S., Ferraro, T., Olsson, J., Rowley, M. J., and Harley, V. R. (2000) Diabetes 49, 555-561
57. Mackay, I. R., Whittingham, S., Fida, S., Myers, M., Ikuno, N., Gershwin, M. E., and Rowley, M. J. (2000) Immunol. Rev. 174, 226-237
58. Güre, A., Stocker, E., Scanlan, M., Keresztes, R., Jäger, D., Altorki, N., Old, L., and Chen, Y.-T. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4198-4203
59. Kemp, E. H., Gawkrodger, D. J., MacNeil, S., Watson, P. F., and Weetman, A. P. (1997) J. Invest. Dermatol. 109, 69-73