Autoantibodies to tyrosinase-related protein-1 detected in the sera of vitiligo patients using a quantitative radiobinding assay

British Journal of Dermatology

Volumn 139, Issue 5, 1998, Pages 798-805

  Kemp, E H ^a   Waterman, E A ^a   Gawkrodger, D J ^b   Watson, P F ^a   Weetman, A P ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CROSS REACTING ANTIBODY; MONOPHENOL MONOOXYGENASE; TYROSINASE RELATED PROTEIN 1; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIBODY DETECTION; ARTICLE; CONTROLLED STUDY; CROSS REACTION; FEMALE; GRAVES DISEASE; HUMAN; HYPOTHYROIDISM; MAJOR CLINICAL STUDY; MALE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; RADIOIMMUNOASSAY; VITILIGO;

ADOLESCENT; ADULT; AGED; AUTOANTIBODIES; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GRAVES DISEASE; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASES; PROTEIN BIOSYNTHESIS; PROTEINS; RADIOIMMUNOASSAY; THYROIDITIS, AUTOIMMUNE; TRANSCRIPTION, GENETIC; VITILIGO;

EID: 0031771838     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1998.02503.x     Document Type: Article

References (29)

1. Naughton GK, Eisinger M, Bystryn JC. Detection of antibodies to melanocytes in vitiligo by specific immunoprecipitation. J Invest Dermatol 1983; 81: 540-2.
2. Naughton GK, Reggiardo D, Bystryn JC. Correlation between vitiligo antibodies and extent of depigmentation in vitiligo. J Am Acad Dermatol 1986; 15: 978-81.
3. Harning R, Cui J, Bystryn JC. Relation between the incidence and level of pigment cell antibodies and disease activity in vitiligo. J Invest Dermatol 1991; 97: 1078-80.
4. Norris DA, Kissinger RM, Naughton GK, Bystryn JC. Evidence for immunologic mechanisms in human vitiligo: patients' sera induce damage to human melanocytes in vitro by complement-mediated damage and antibody-dependent cellular cytotoxicity (ADDC). J Invest Dermatol 1988; 90: 783-9.
5. Cui J, Harning R, Henn M, Bystryn JC. Identification of pigment cell antigens defined by vitiligo antibodies. J Invest Dermatol 1992; 98: 162-5.
6. Song Y-H, Connor E, Li Y et al. The role of tyrosinase in autoimmune vitiligo. Lancet 1994; 344: 1049-52.
7. Baharav E, Merimski O, Shoenfeld Y et al. Tyrosinase as an autoantigen in patients with vitiligo. Clin Exp Immunol 1996; 105: 84-8.
8. 35S-labelled recombinant human tyrosinase in a radioimmunoassay. J Invest Dermatol 1997; 109: 69-73.
9. Kemp KH, Gawkrodger DJ, Watson PF, Weetman AP. Immunoprecipitation of melanogenic enzyme autoantigens with vitiligo sera: evidence for cross-reactive autoantibodies to tyrosinase and tyrosinase-related protein-2 (TRP-2). Clin Exp Immunol 1997; 109: 495-500.
10. Austin LM, Boissy RE. Mammalian tyrosinase-related protein-1 is recognised by autoantibodies from vitiliginous Smyth chickens. Am J Pathol 1995; 146: 1529-41.
11. Cui J, Arita Y, Bystryn JC. Characterisation of vitiligo antigens. Pigment Cell Res 1995; 8: 53-9.
12. Falorni A, Grubin CE, Takei I et al. Radioimmunoassay detects the frequent occurrence of autoantibodies to the Mr 65,000 isoform of glutamic acid decarboxylase in Japanese insulin-dependent diabetes. Autoimmunity 1994; 19: 113-25.
13. Falorni A, Nikoshokov A, Laureti S et al. High diagnostic accuracy for idiopathic Addison's disease with a sensitive radiobinding assay for autoantibodies against recombinant human 21-hydroxylase. J Clin Endocrinol Metab 1995; 80: 2752-5.
14. Peterson P, Perheentupa J, Krohn KJE. Detection of candidal antigens in autoimmune polyglandular syndrome type I. Clin Diag Lab Immunol 1996; 3: 290-4.
15. Li Y, Song Y-H, Rais N et al. Autoantibodies to the extracellular domain of the calcium sensing receptor in patients with acquired hypoparathyroidism. J Clin Invest 1996; 97: 910-14.
16. Tsukamoto K, Jackson IJ, Urabe K et al. A second tyrosinase-related protein. TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase. EMBO J 1992; 11: 519-26.
17. Tomita Y, Shibahara S, Takeda A et al. The monoclonal antibodies TMH-1 and TMH-2 specifically bind to a protein encoded at the murine b-locus, not to a protein encoded at the c-locus. J Invest Dermatol 1991; 96: 500-4.
18. Thomson TM, Mattes JM, Roux L et al. Pigmentation-associated glycoprotein of human melanomas and melanocytes: definition with a mouse monoclonal antibody. J Invest Dermatol 1985; 85: 169-74.
19. Takimoto H, Suzuki S, Masui S et al. MAT-1, a monoclonal antibody that specifically recognises human tyrosinase. J Invest Dermatol 1995; 105: 754-68.
20. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
21. Yokoyama K, Suzuki H, Yasumoto K et al. Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2. Biochim Biophys Acta 1994; 1217: 317-21.
22. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding. Anal Biochem 1976; 72: 248-54.
23. Cohen T, Muller RM, Tomita Y, Shibahara S. Nucleolide sequence of the cDNA encoding human tyrosinase-related protein. Nucleic Acids Res 1990; 18: 2807-8.
24. Vijayasaradhi S, Doskoch PM, Houghton AN. Biosynthesis and intracellular movement of the melanosomal membrane glycoprotein gp75, the human b (Brown) locus product. Exp Cell Res 1991; 196: 233-40.
25. Jimenez M, Kameyama K, Maloy WE et al. Mammalian tyrosinase: biosynthesis, processing, and modulation by melanocyte-stimulating hormone. Proc Natl Acad Sci USA 1989; 85: 3830-4.
26. Kwon BS, Pigmentation genes: the tyrosinase gene family and the pmel 17 gene family. J Invest Dermatol 1993; 100: 134-40S.
27. Brichard V, Van Pel A, Wolfel T et al. The tyrosinase gene encodes for an antigen recognised by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J Exp Med 1993; 178: 489-95.
28. Wang RF, Robbins PF, Kawakami Y et al. Identification of a gene encoding a melanoma tumor antigen recognised by HLA-A31-restricted tumor-infiltrating lymphocytes. J Exp Med 1995; 181: 799-804.
29. Wang RF, Apella E, Kawakami Y et al. Identification of TRP-2 as a human tumor antigen recognised by cytotoxic T lymphocytes. J Exp Med 1996; 184: 2207-16.