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Volumn 174, Issue , 2000, Pages 226-237

The peculiar autoimmunity of primary biliary cirrhosis

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOACID DEHYDROGENASE; AUTOANTIBODY; AUTOANTIGEN; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; EPITOPE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN M; MITOCHONDRION ANTIBODY; MONOCLONAL ANTIBODY; NUCLEAR PROTEIN; PEPTIDE LIBRARY; PYRUVATE DEHYDROGENASE COMPLEX;

EID: 0034085812     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0528.2002.017410.x     Document Type: Review
Times cited : (83)

References (65)
  • 1
    • 0026034491 scopus 로고
    • Primary biliary cirrhosis: Paradigm or paradox for autoimmunity
    • 1. Gershwin ME, Mackay IR. Primary biliary cirrhosis: paradigm or paradox for autoimmunity. Gastroenterology 1991;100:822-833.
    • (1991) Gastroenterology , vol.100 , pp. 822-833
    • Gershwin, M.E.1    Mackay, I.R.2
  • 2
    • 0002578270 scopus 로고
    • Clinical, immunologic and molecular features of primay biliary cirrhosis
    • 2. Gershwin ME, Mackay I, Coppel R, Nakanuma Y. Clinical, immunologic and molecular features of primay biliary cirrhosis. Semin Clin Immunol 1994;7:5-16.
    • (1994) Semin Clin Immunol , vol.7 , pp. 5-16
    • Gershwin, M.E.1    Mackay, I.2    Coppel, R.3    Nakanuma, Y.4
  • 3
    • 0000675633 scopus 로고
    • Primary biliary cirrhosis showing a high titer of autoantibody
    • 3. Mackay IR. Primary biliary cirrhosis showing a high titer of autoantibody. N Engl J Med 1958;258:185-187.
    • (1958) N Engl J Med , vol.258 , pp. 185-187
    • Mackay, I.R.1
  • 4
    • 50549218780 scopus 로고
    • Serological tests in diagnosis of primary biliary cirrhosis
    • 4. Walker JG, Doniach D, Roitt IM, Sherlock S. Serological tests in diagnosis of primary biliary cirrhosis. Lancet 1965;i:827-831.
    • (1965) Lancet , vol.1 , pp. 827-831
    • Walker, J.G.1    Doniach, D.2    Roitt, I.M.3    Sherlock, S.4
  • 5
    • 0028856144 scopus 로고
    • Mitochondrial antigen/antibody system in primary biliary cirrhosis: Revisited
    • 5. Berg PA, Klein R. Mitochondrial antigen/antibody system in primary biliary cirrhosis: revisited. Liver 1995;15:281-292.
    • (1995) Liver , vol.15 , pp. 281-292
    • Berg, P.A.1    Klein, R.2
  • 6
    • 0023267078 scopus 로고
    • Identification and specificity of a cDNA encoding the 70 kD mitochondrial antigen recognized in primary biliary cirrhosis
    • 6. Gershwin ME, Mackay IR, Sturgess A, Coppel RL. Identification and specificity of a cDNA encoding the 70 kD mitochondrial antigen recognized in primary biliary cirrhosis. J Immunol 1987;138:3525-3531.
    • (1987) J Immunol , vol.138 , pp. 3525-3531
    • Gershwin, M.E.1    Mackay, I.R.2    Sturgess, A.3    Coppel, R.L.4
  • 7
    • 0000914116 scopus 로고
    • Primary biliary cirrhosis. Chronic non-suppurative destructive cholangitis
    • 7. Rubin E, Schaffner F, Popper H. Primary biliary cirrhosis. Chronic non-suppurative destructive cholangitis. Am J Pathol 1965;46:387-407.
    • (1965) Am J Pathol , vol.46 , pp. 387-407
    • Rubin, E.1    Schaffner, F.2    Popper, H.3
  • 9
    • 0033036094 scopus 로고    scopus 로고
    • Ten-year survival in ursodeoxycholic acid-treated patients with primary biliary cirrhosis
    • 9. Poupon RE, Bonnand AM, Chretien Y. The UDCA-PBC Study Group. Ten-year survival in ursodeoxycholic acid-treated patients with primary biliary cirrhosis. Hepatology 1999;29:1668-1671.
    • (1999) Hepatology , vol.29 , pp. 1668-1671
    • Poupon, R.E.1    Bonnand, A.M.2    Chretien, Y.3
  • 10
    • 0026352217 scopus 로고
    • Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration
    • 10. Crosignani A, Podda M, Battezzati PM. Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration. Hepatology 1991;14:1000-1007.
    • (1991) Hepatology , vol.14 , pp. 1000-1007
    • Crosignani, A.1    Podda, M.2    Battezzati, P.M.3
  • 11
    • 0031005366 scopus 로고    scopus 로고
    • Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis
    • 11. Koga H, Sakisaka S, Ohishi M, Sata M, Tanikawa K. Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis. Hepatology 1997;25:1077-1084.
    • (1997) Hepatology , vol.25 , pp. 1077-1084
    • Koga, H.1    Sakisaka, S.2    Ohishi, M.3    Sata, M.4    Tanikawa, K.5
  • 13
    • 0026054966 scopus 로고
    • Hepatocellular and biliary expression of HLA antigens in primary biliary cirrhosis before and after ursodeoxycholic acid therapy
    • 13. Terasaki S, Nakanuma Y, Ogino H, Unoura M, Kobayashi K. Hepatocellular and biliary expression of HLA antigens in primary biliary cirrhosis before and after ursodeoxycholic acid therapy. Am J Gastroenterol 1991;86:1194-1199.
    • (1991) Am J Gastroenterol , vol.86 , pp. 1194-1199
    • Terasaki, S.1    Nakanuma, Y.2    Ogino, H.3    Unoura, M.4    Kobayashi, K.5
  • 15
    • 0033026044 scopus 로고    scopus 로고
    • Ursodeoxycholic acid inhibits eosinophil degranulation in patients with primary biliary cirrhosis
    • 15. Yamazaki K, et al. Ursodeoxycholic acid inhibits eosinophil degranulation in patients with primary biliary cirrhosis. Hepatology 1999;30:71-78.
    • (1999) Hepatology , vol.30 , pp. 71-78
    • Yamazaki, K.1
  • 16
    • 0032932588 scopus 로고    scopus 로고
    • The geoepidemiology of primary biliary cirrhosis: Contrasts and comparisons with the spectrum of autoimmune diseases
    • 16. Parikh-Patel A, Gold E, Mackay IR, Gershwin ME. The geoepidemiology of primary biliary cirrhosis: contrasts and comparisons with the spectrum of autoimmune diseases. Clin Immunol 1999;91:206-218.
    • (1999) Clin Immunol , vol.91 , pp. 206-218
    • Parikh-Patel, A.1    Gold, E.2    Mackay, I.R.3    Gershwin, M.E.4
  • 17
    • 0034031785 scopus 로고    scopus 로고
    • Primary biliary cirrhosis: An orchestrated immune response against epithelial cells
    • 17. Gershwin ME, et al. Primary biliary cirrhosis: an orchestrated immune response against epithelial cells. Immunol Rev 2000;174:210-225.
    • (2000) Immunol Rev , vol.174 , pp. 210-225
    • Gershwin, M.E.1
  • 18
    • 0001849089 scopus 로고    scopus 로고
    • Primary biliary cirrhosis
    • Karawitt EL, Wiesner RH, Nishioka M, eds. Amsterdam: Elsevier
    • 18. Mackay IR, Gershwin ME. Primary biliary cirrhosis. In: Karawitt EL, Wiesner RH, Nishioka M, eds. Autoimmune liver diseases. Amsterdam: Elsevier; 1998. p. 49-69.
    • (1998) Autoimmune Liver Diseases , pp. 49-69
    • Mackay, I.R.1    Gershwin, M.E.2
  • 19
    • 0026660952 scopus 로고
    • Antimitochondrial antibodies in kindreds of patients with PBC, AMA are unique to clinical disease and are absent in asymptomatic family members
    • 19. Caldwell SH, et al. Antimitochondrial antibodies in kindreds of patients with PBC, AMA are unique to clinical disease and are absent in asymptomatic family members. Hepatology 1992;16:899-905.
    • (1992) Hepatology , vol.16 , pp. 899-905
    • Caldwell, S.H.1
  • 20
    • 0034006830 scopus 로고    scopus 로고
    • Autoimmune disease overlaps and the liver: Two for price of one?
    • In press
    • 20. Mackay IR. Autoimmune disease overlaps and the liver: two for price of one? J Gastroenterol Hepatol (In press).
    • J Gastroenterol Hepatol
    • Mackay, I.R.1
  • 21
    • 0002436702 scopus 로고    scopus 로고
    • Antimitochondrial and other autoantibodies in primary biliary cirrhosis
    • Krawitt EL, Wiesner RH, Nishioka M, eds. Amsterdam: Elsevier
    • 21. Bassendine MF, Jones DEJ. Antimitochondrial and other autoantibodies in primary biliary cirrhosis. In: Krawitt EL, Wiesner RH, Nishioka M, eds. Autoimmune liver diseases. 2nd ed. Amsterdam: Elsevier; 1998. p. 287-304.
    • (1998) Autoimmune Liver Diseases. 2nd Ed. , pp. 287-304
    • Bassendine, M.F.1    Jones, D.E.J.2
  • 22
    • 0023937932 scopus 로고
    • The predominance of IgG3 and IgM isotype antimitochondrial antibodies against recombinant fused mitochondrial polypeptide in patients with primary biliary cirrhosis
    • 22. Surh CD, et al. The predominance of IgG3 and IgM isotype antimitochondrial antibodies against recombinant fused mitochondrial polypeptide in patients with primary biliary cirrhosis. Hepatology 1988;8:290-295.
    • (1988) Hepatology , vol.8 , pp. 290-295
    • Surh, C.D.1
  • 23
    • 0032839377 scopus 로고    scopus 로고
    • Frequency of IgG, IgM and IgA class autoantibodies against 2-oxo-acid dehydrogenase complex in 102 Japanese patients with primary biliary cirrhosis
    • 23. Kinoshita H, Omagari K, Matsuo I, Yamaguchi K, Ikuno N, Kohno S. Frequency of IgG, IgM and IgA class autoantibodies against 2-oxo-acid dehydrogenase complex in 102 Japanese patients with primary biliary cirrhosis. Hepatol Res 1999;15:163-171.
    • (1999) Hepatol Res , vol.15 , pp. 163-171
    • Kinoshita, H.1    Omagari, K.2    Matsuo, I.3    Yamaguchi, K.4    Ikuno, N.5    Kohno, S.6
  • 26
    • 0033963610 scopus 로고    scopus 로고
    • Enzyme inhibitory antibody to pyruvate dehydrogenase: Diagnostic utility in primary biliary cirrhosis
    • In press
    • 26. Jois J, Omagari K, Rowley MJ, Mackay IR. Enzyme inhibitory antibody to pyruvate dehydrogenase: diagnostic utility in primary biliary cirrhosis. Ann Clin Biochem (In press).
    • Ann Clin Biochem
    • Jois, J.1    Omagari, K.2    Rowley, M.J.3    Mackay, I.R.4
  • 27
    • 0028213843 scopus 로고
    • Enzyme inhibitory autoantibodies to pyruvate dehydrogenase complex in primary biliary cirrhosis differ for mammalian, yeast and bacterial enzymes: Implications for molecular mimicry
    • 27. Teoh K-L, Mackay IR, Rowley MJ, Fussey SPM. Enzyme inhibitory autoantibodies to pyruvate dehydrogenase complex in primary biliary cirrhosis differ for mammalian, yeast and bacterial enzymes: implications for molecular mimicry. Hepatology 1994;19:1029-1033.
    • (1994) Hepatology , vol.19 , pp. 1029-1033
    • Teoh, K.-L.1    Mackay, I.R.2    Rowley, M.J.3    Fussey, S.P.M.4
  • 30
    • 0031747413 scopus 로고    scopus 로고
    • Natural and disease-associated autoantibodies to the autoantigen, dihydrolipoamide acetyltransferase, recognise different epitopes
    • 30. Chen Q-Y, Mackay IR, Fida S, Myers MA, Rowley MJ. Natural and disease-associated autoantibodies to the autoantigen, dihydrolipoamide acetyltransferase, recognise different epitopes. J Autoimmun 1998;11:51-161.
    • (1998) J Autoimmun , vol.11 , pp. 51-161
    • Chen, Q.-Y.1    Mackay, I.R.2    Fida, S.3    Myers, M.A.4    Rowley, M.J.5
  • 31
    • 0026539685 scopus 로고
    • Differing epitope selection of experimentally induced and natural antibodies to a disease-specific autoantigen, the E2 subunit of pyruvate dehydrogenase complex
    • 31. Rowley MJ, et al. Differing epitope selection of experimentally induced and natural antibodies to a disease-specific autoantigen, the E2 subunit of pyruvate dehydrogenase complex. Int Immunol 1992;4:1245-1253.
    • (1992) Int Immunol , vol.4 , pp. 1245-1253
    • Rowley, M.J.1
  • 32
    • 0033000884 scopus 로고    scopus 로고
    • Characterization of the autoantibody responses to recombinant E3 binding protein (protein x) of pyruvate dehydrogenase in primary biliary cirrhosis
    • 32. Palmer JM, Jones DEJ, Quinn J, McHugh A, Yeaman SJ. Characterization of the autoantibody responses to recombinant E3 binding protein (protein x) of pyruvate dehydrogenase in primary biliary cirrhosis. Hepatology 1999;30:21-26.
    • (1999) Hepatology , vol.30 , pp. 21-26
    • Palmer, J.M.1    Jones, D.E.J.2    Quinn, J.3    McHugh, A.4    Yeaman, S.J.5
  • 33
    • 0021949689 scopus 로고
    • Hybrids from normal, germ-free nude and neonatal mice produce monoclonal antibodies to eight different intracellular structures
    • 33. Underwood JR, Pedersen J, Chalmers PJ, Toh B-H. Hybrids from normal, germ-free nude and neonatal mice produce monoclonal antibodies to eight different intracellular structures. Clin Exp Immunol 1985;60:417-426.
    • (1985) Clin Exp Immunol , vol.60 , pp. 417-426
    • Underwood, J.R.1    Pedersen, J.2    Chalmers, P.J.3    Toh, B.-H.4
  • 34
    • 0023866247 scopus 로고
    • Murine monoclonal antibody to michondria reacts with the 72 kD antigen of primary biliary cirrhosis
    • 34. Mu F-T, Alderuccio F, Toh B-H, Gershwin ME, Coppel R, Mackay IR. Murine monoclonal antibody to michondria reacts with the 72 kD antigen of primary biliary cirrhosis. Clin Exp Immunol 1988;71:100-106.
    • (1988) Clin Exp Immunol , vol.71 , pp. 100-106
    • Mu, F.-T.1    Alderuccio, F.2    Toh, B.-H.3    Gershwin, M.E.4    Coppel, R.5    Mackay, I.R.6
  • 36
    • 9844260067 scopus 로고    scopus 로고
    • Primary biliary cirrhosis an epithelitis: Evidence of abnormal salivary gland immunohistochemistry
    • 36. Tsuneyama K, et al. Primary biliary cirrhosis an epithelitis: evidence of abnormal salivary gland immunohistochemistry. Autoimmunity 1997;26:23-31.
    • (1997) Autoimmunity , vol.26 , pp. 23-31
    • Tsuneyama, K.1
  • 37
    • 0031972178 scopus 로고    scopus 로고
    • Immunogenetic analysis of a panel of monoclonal IgG and IgM anti-PDC-E2/X antibodies derived from patients with primary biliary cirrhosis
    • 37. Thomson RK, et al. Immunogenetic analysis of a panel of monoclonal IgG and IgM anti-PDC-E2/X antibodies derived from patients with primary biliary cirrhosis. J Hepatol 1998;28:582-594.
    • (1998) J Hepatol , vol.28 , pp. 582-594
    • Thomson, R.K.1
  • 38
    • 0024503374 scopus 로고
    • Immunization of experimental animals with dihydrolipoamide acetyltransferase, as a purified recombinant polypeptide, generates mitochondrial antibodies but not primary biliary cirrhosis
    • 38. Krams SM, Surh CD, Coppel RL, Ansari A, Ruebner B, Gershwin ME. Immunization of experimental animals with dihydrolipoamide acetyltransferase, as a purified recombinant polypeptide, generates mitochondrial antibodies but not primary biliary cirrhosis. Hepatology 1989;9:411-436.
    • (1989) Hepatology , vol.9 , pp. 411-436
    • Krams, S.M.1    Surh, C.D.2    Coppel, R.L.3    Ansari, A.4    Ruebner, B.5    Gershwin, M.E.6
  • 39
    • 0025887238 scopus 로고
    • Inhibitory antibody to a conformational epitope of the pyruvate dehydrogenase complex, the major autoantigen in primary biliary cirrhosis
    • 39. Rowley MJ, McNeilage LJ, Armstrong JM, Mackay IR. Inhibitory antibody to a conformational epitope of the pyruvate dehydrogenase complex, the major autoantigen in primary biliary cirrhosis. Clin Immunol Immunopathol 1991;60:356-370.
    • (1991) Clin Immunol Immunopathol , vol.60 , pp. 356-370
    • Rowley, M.J.1    McNeilage, L.J.2    Armstrong, J.M.3    Mackay, I.R.4
  • 40
    • 0027484975 scopus 로고
    • The role of the 16/6 idiotype network in the induction and manifestation of systemic lupus erythematosus
    • 40. Waisman A, Medlovic S, Ruiz PJ, Meshorer A, Mozes I. The role of the 16/6 idiotype network in the induction and manifestation of systemic lupus erythematosus. Int Immunol 1993;5:1293-1300.
    • (1993) Int Immunol , vol.5 , pp. 1293-1300
    • Waisman, A.1    Medlovic, S.2    Ruiz, P.J.3    Meshorer, A.4    Mozes, I.5
  • 41
    • 0032978466 scopus 로고    scopus 로고
    • Anti-idiotypic antibodies to anti-PDC-E2 in primary biliary cirrhosis and normal subjects
    • 41. Chen Q-Y, Rowley MJ, Mackay IR. Anti-idiotypic antibodies to anti-PDC-E2 in primary biliary cirrhosis and normal subjects. Hepatology 1999;29:624-631.
    • (1999) Hepatology , vol.29 , pp. 624-631
    • Chen, Q.-Y.1    Rowley, M.J.2    Mackay, I.R.3
  • 42
    • 0017862197 scopus 로고
    • Circulating immune complexes and complement activation in primary biliary cirrhosis
    • 42. Wands JR, Dienstag JL, Bhan AK, Feller ER, Isselbacher KJ. Circulating immune complexes and complement activation in primary biliary cirrhosis. N Engl J Med 1978;298:233-237.
    • (1978) N Engl J Med , vol.298 , pp. 233-237
    • Wands, J.R.1    Dienstag, J.L.2    Bhan, A.K.3    Feller, E.R.4    Isselbacher, K.J.5
  • 43
    • 0001492925 scopus 로고
    • Nuclear antibodies in primary biliary cirrhosis
    • Meyer zum Buschenfelde K-H, Hoofnagle J, Manns M, eds. Dordrecht: Kluwer
    • 43. Mackay IR, Rowley MJ, Whittingham S. Nuclear antibodies in primary biliary cirrhosis. In: Meyer zum Buschenfelde K-H, Hoofnagle J, Manns M, eds. Immunology and liver. Falk Symposium 70. Dordrecht: Kluwer; 1993. p. 379-409.
    • (1993) Immunology and Liver. Falk Symposium , vol.70 , pp. 379-409
    • Mackay, I.R.1    Rowley, M.J.2    Whittingham, S.3
  • 44
    • 0033065803 scopus 로고    scopus 로고
    • Autoimmune cholangitis and primary biliary cirrhosis - An autoimmune enigma
    • 44. Kinoshita H, et al. Autoimmune cholangitis and primary biliary cirrhosis - an autoimmune enigma. Liver 1999;14:122-128.
    • (1999) Liver , vol.14 , pp. 122-128
    • Kinoshita, H.1
  • 45
    • 0026650005 scopus 로고
    • CENP-C, an autoantigen in scleroderma is a component of the human inner kinetochore plate
    • 45. Saitoh H, et al. CENP-C, an autoantigen in scleroderma is a component of the human inner kinetochore plate. Cell 1992;70:115-125.
    • (1992) Cell , vol.70 , pp. 115-125
    • Saitoh, H.1
  • 46
    • 0029143661 scopus 로고
    • High prevalence of antibodies to recombinant CENP-B in primary biliary cirrhosis: Nuclear immunofluorescence patterns and ELISA reactivities
    • 46. Parveen S, Morshed SA, Nishioka M. High prevalence of antibodies to recombinant CENP-B in primary biliary cirrhosis: nuclear immunofluorescence patterns and ELISA reactivities. J Gastroenterol Hepatol 1995;10:438-445.
    • (1995) J Gastroenterol Hepatol , vol.10 , pp. 438-445
    • Parveen, S.1    Morshed, S.A.2    Nishioka, M.3
  • 47
    • 0028298177 scopus 로고
    • The association of primary biliary cirrhosis and systemic sclerosis is not accounted for by cross reactivity between mitochondrial and centromere antigens
    • 47. Whyte J, Hough D, Maddison PJ, McHugh NJ. The association of primary biliary cirrhosis and systemic sclerosis is not accounted for by cross reactivity between mitochondrial and centromere antigens. J Autoimmun 1994;7:413-124.
    • (1994) J Autoimmun , vol.7 , pp. 413-1124
    • Whyte, J.1    Hough, D.2    Maddison, P.J.3    McHugh, N.J.4
  • 48
    • 0030903041 scopus 로고    scopus 로고
    • Nuclear and envelope protein autoantibodies in primary biliary cirrhosis
    • 48. Courvalin J-C, Worman H. Nuclear and envelope protein autoantibodies in primary biliary cirrhosis. Semin Liver Dis 1997;17:79-88.
    • (1997) Semin Liver Dis , vol.17 , pp. 79-88
    • Courvalin, J.-C.1    Worman, H.2
  • 49
    • 0029082348 scopus 로고
    • Autoantibodies from patients with primary biliary cirrhosis preferentially react with the amino-terminal domain of nuclear pore complex glycoprotein gp210
    • 49. Wisierska-Gadek J, Hohenauer H, Hitchman E, Penner E. Autoantibodies from patients with primary biliary cirrhosis preferentially react with the amino-terminal domain of nuclear pore complex glycoprotein gp210. J Exp Med 1995;182:1159-1162.
    • (1995) J Exp Med , vol.182 , pp. 1159-1162
    • Wisierska-Gadek, J.1    Hohenauer, H.2    Hitchman, E.3    Penner, E.4
  • 50
    • 0030965839 scopus 로고    scopus 로고
    • Autoantibodies against nuclear dots in primary biliary cirrhosis
    • 50. Szostecki C, Guldner HH, Will H. Autoantibodies against nuclear dots in primary biliary cirrhosis. Semin Liver Dis 1997;17:71-78.
    • (1997) Semin Liver Dis , vol.17 , pp. 71-78
    • Szostecki, C.1    Guldner, H.H.2    Will, H.3
  • 51
    • 0033617169 scopus 로고    scopus 로고
    • The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization and modification by small ubiquitin-like modifiers
    • 51. Sternsdorf T, Jensen K, Reich B, Will H. The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization and modification by small ubiquitin-like modifiers. J Biol Chem 1999;274:12555-12566.
    • (1999) J Biol Chem , vol.274 , pp. 12555-12566
    • Sternsdorf, T.1    Jensen, K.2    Reich, B.3    Will, H.4
  • 52
    • 0344958748 scopus 로고    scopus 로고
    • Identification of major linear epitopes on the sp100 nuclear PBC autoantigen by the gene-fragment phage-display technology
    • 52. Blüthner M, Schäfer C, Schneider C, Bautz FA. Identification of major linear epitopes on the sp100 nuclear PBC autoantigen by the gene-fragment phage-display technology. Autoimmunity 1999;29:33-42.
    • (1999) Autoimmunity , vol.29 , pp. 33-42
    • Blüthner, M.1    Schäfer, C.2    Schneider, C.3    Bautz, F.A.4
  • 54
    • 0013649347 scopus 로고    scopus 로고
    • The SRY-related protein, SOX13, is a diabetes autoantigen expressed in pancreatic islets
    • In press
    • 54. Kasimiotis H, et al. The SRY-related protein, SOX13, is a diabetes autoantigen expressed in pancreatic islets. Diabetes (In press).
    • Diabetes
    • Kasimiotis, H.1
  • 55
    • 0032536804 scopus 로고    scopus 로고
    • CDNA cloning of a novel rainbow trout SRY-type HMG domain protein, rtSOX23, and its functional analysis
    • 55. Yamashita A, et al. CDNA cloning of a novel rainbow trout SRY-type HMG domain protein, rtSOX23, and its functional analysis. Gene 1998;209:193-200.
    • (1998) Gene , vol.209 , pp. 193-200
    • Yamashita, A.1
  • 56
    • 0023772131 scopus 로고    scopus 로고
    • The autoepitope of the 74 Kd mitochondrial autoamigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase
    • 56. Van de Water J, Gershwin ME, Leung P, Ansari A, Coppel RL. The autoepitope of the 74 Kd mitochondrial autoamigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. J Exp Med 1998;67:1791-1799.
    • (1998) J Exp Med , vol.67 , pp. 1791-1799
    • Van De Water, J.1    Gershwin, M.E.2    Leung, P.3    Ansari, A.4    Coppel, R.L.5
  • 57
    • 0025340632 scopus 로고
    • Reactivity of primary biliary cirrhosis sera with Escherichia coli dihydrolipoamide acetyltransferase (E2p): Characterization of the main immunogenic region
    • 57. Fussey SMP, Ali ST, Guest JR, James OFW, Bassendine MF, Yeaman SJ. Reactivity of primary biliary cirrhosis sera with Escherichia coli dihydrolipoamide acetyltransferase (E2p): characterization of the main immunogenic region. Proc Natl Acad Sci USA 1990;87:3987-3991.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3987-3991
    • Fussey, S.M.P.1    Ali, S.T.2    Guest, J.R.3    James, O.F.W.4    Bassendine, M.F.5    Yeaman, S.J.6
  • 58
    • 0031748099 scopus 로고    scopus 로고
    • Immunoreactivity of porcine heart dihydrolipoamide acetyl- and succinyl-transferases (PDC-E2, OGDC-E2) with primary biliary cirrhosis sera: Characterization of the autoantigenic region and effects of enzymatic delipoylation and relipoylation
    • 58. Koike K, Ishibashi H, Koike M. Immunoreactivity of porcine heart dihydrolipoamide acetyl-and succinyl-transferases (PDC-E2, OGDC-E2) with primary biliary cirrhosis sera: characterization of the autoantigenic region and effects of enzymatic delipoylation and relipoylation. Hepatology 1998;27:1467-1474.
    • (1998) Hepatology , vol.27 , pp. 1467-1474
    • Koike, K.1    Ishibashi, H.2    Koike, M.3
  • 60
    • 0032770732 scopus 로고    scopus 로고
    • Towards the pathogenesis of autoimmune liver disease
    • 60. Mackay IR, Davies JM, Rowley MJ. Towards the pathogenesis of autoimmune liver disease. J Autoimmun 1999;13:163-169.
    • (1999) J Autoimmun , vol.13 , pp. 163-169
    • Mackay, I.R.1    Davies, J.M.2    Rowley, M.J.3
  • 61
    • 0031781602 scopus 로고    scopus 로고
    • Three-dimensional structure of the major autoantigen in primary biliary cirrhosis
    • 61. Howard MJ, et al. Three-dimensional structure of the major autoantigen in primary biliary cirrhosis. Gastroenterology 1998;115:139-146.
    • (1998) Gastroenterology , vol.115 , pp. 139-146
    • Howard, M.J.1
  • 62
    • 0034653534 scopus 로고    scopus 로고
    • Prediction of the immunodominant epitope of the pyruvate dehydrogenase complex-E2 (PDC-E2) in primary biliary cirrhosis using phage display
    • In press
    • 62. Rowley MJ, et al. Prediction of the immunodominant epitope of the pyruvate dehydrogenase complex-E2 (PDC-E2) in primary biliary cirrhosis using phage display. J Immunol (In press).
    • J Immunol
    • Rowley, M.J.1
  • 63
    • 16044368747 scopus 로고    scopus 로고
    • Random phage mimotopes recognized by monoclonal antibodies against the pyruvate dehydrogenase complex-E2 (PDC-E2)
    • 63. Cha S, et al. Random phage mimotopes recognized by monoclonal antibodies against the pyruvate dehydrogenase complex-E2 (PDC-E2). Proc Natl Acad Sci USA 1996;93:10949-10954.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10949-10954
    • Cha, S.1
  • 64
    • 0030462423 scopus 로고    scopus 로고
    • Inhibition of PDC-E2 human combinatorial autoantibodies by peptide mimotopes
    • 64. Leung PSC, et al. Inhibition of PDC-E2 human combinatorial autoantibodies by peptide mimotopes. J Autoimmun 1996;9:785-793.
    • (1996) J Autoimmun , vol.9 , pp. 785-793
    • Leung, P.S.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.