Pex11p plays a primary role in medium-chain fatty acid oxidation, a process that affects peroxisome number and size in saccharomyces cerevisiae

Journal of Cell Biology

Volumn 150, Issue 3, 2000, Pages 489-497

  Van Roermund, C W T ^a   Tabak, H F ^a   Van den Berg, M ^a   Wanders, R J A ^a   Hettema, E H ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

oxidation; Morphology; Organelle multiplication; Peroxin; Peroxisome

Indexed keywords

GLUCOSE; MEDIUM CHAIN FATTY ACID; MEMBRANE PROTEIN; OLEIC ACID; PROTEIN PEX11P; UNCLASSIFIED DRUG;

ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; FATTY ACID OXIDATION; NONHUMAN; PEROXISOME; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ACYL-COA OXIDASE; COENZYME A LIGASES; FATTY ACIDS; MEMBRANE PROTEINS; MUTATION; OLEIC ACID; OXIDATION-REDUCTION; OXIDOREDUCTASES; PEROXISOMES; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 0034617992     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.150.3.489     Document Type: Article

References (39)

1. Nuclear hormone receptors arose from pre-existing protein modules during evolution
2. Metabolic control of peroxisome abundance
3. A unified nomenclature for peroxisome biogenesis factors
4. Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
5. Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p
6. Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene
7. Peroxisomal protein import is conserved between yeast, insects and mammals
8. The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae
9. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
10. Proteinase mutants of Saccharomyces cerevisiae
11. Dynamics of gene expression revealed by comparison of serial analysis of gene expression transcripts profiles from yeast grown on two different carbon sources
12. Global regulatory functions of Oaf1p and Pip2p (Oaf2p), transcription factors that regulate genes encoding peroxisomal proteins in Saccharomyces cerevisiae
13. Biochemical studies of three Saccharomyces cerevisiae acyl-CoA synthetases, Faa1p, Faa2p and Faa3p
14. β-oxidation of fatty acids in mitochondria, peroxisomes and bacteria: A century of continued progress
15. Targeted disruption of the a isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
16. Elongation and clustering of glycosomes in Trypanosoma brucei overexpressing the glycosomal Pex11p
17. Pmp27 promotes peroxisome proliferation
18. Redox-sensirive homodimerization of Pex11p: A proposed mechanism to regulate peroxisomal division
19. Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis
20. Peroxisome biogenesis: Involvement of ARF and coatomer
21. A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy)
22. Peroxisomal disorders: Genotype, phenotype, major neuropathologic lesions, and pathogenesis
23. Absence of spontaneous peroxisome proliferation in enoyl-CoA hydratase/L-3-hydroxyacyl-CoA dehydrogenase-deficient mouse liver. Further support for the role of fatty acyl CoA oxidase in PPARα ligand metabolism
24. Pip2p: A transcriptional regulator of peroxisome proliferation in the yeast Saccharomyces cerevisiae
25. 6 transcription factors Pip2p and Oaf1p controls induction of genes encoding peroxisomal proteins in Saccharomyces cerevisiae
26. The Candida boidinii peroxisomal membrane protein Pmp30 has a role in peroxisome proliferation and is functionally homologous to Pmp27 from Saccharomyces cerevisiae
27. Expression of Pex11β mediates peroxisome proliferation in the absence of extracellular stimuli
28. PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene
29. Measurement of protein using bicinchonic acid
30. D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein deficiency: A newly identified peroxisomal disorder
31. Isolation of peroxisome assembly mutants from Saccharomyces cerevisiae with different morphologies using a novel positive selection procedure
32. Peroxisomal bifunctional protein deficiency revisited: Resolution of its true enzymatic and molecular basis
33. The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD(H) and acetyl-CoA under in vivo conditions
34. Peroxisomal β-oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: Evidence for an isocitrate/2-oxoglutarate NADP redox shuttle
35. Transport of activated fatty acids by the peroxisomal ATP-binding-cassette transporter Pxa2 in a semi-intact yeast cell system
36. PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae
37. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
38. Human trifunctional protein deficiency: A new disorder of mitochondrial fatty acid β-oxidation
39. Peroxisomal disorders: A review