The tetrameric protein transthyretin dissociates to a non-native monomer in solution. A novel model for amyloidogenesis

Journal of Biological Chemistry

Volumn 274, Issue 46, 1999, Pages 32943-32949

  Quintas, Alexandre ^a,b   Saraiva, Maria João M ^c   Britot, Rui M M ^a,d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b INSTITUTO SUPERIOR DE CIÊNCIAS DA SAÚDE EGAS MONIZ   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

PREALBUMIN;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN SPONGIOSIS; CRYSTAL STRUCTURE; GENE REARRANGEMENT; IONIC STRENGTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT;

AMYLOID; AMYLOID NEUROPATHIES; ANILINO NAPHTHALENESULFONATES; CHROMATOGRAPHY, GEL; GUANIDINE; HUMANS; IODIDES; MODELS, MOLECULAR; PREALBUMIN; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SOLUBILITY; SPECTROMETRY, FLUORESCENCE; TRYPTOPHAN;

EID: 0032725562     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.46.32943     Document Type: Article

References (27)

1. Saraiva, M. J. M., Birken, S., Costa, P. P., and Goodman, D. S. (1984) J. Clin. Invest. 74, 104-119
2. Saraiva, M. J. M. (1996) J. Peripheral Nervous System 1, 179-188
3. Vatassery, G. T., Quach, H. T., Smith, W. E., Benson, B. A., and Eckfeldt, J. H. (1991) Clin. Chim. Acta 197 , 19-25
4. Blake, C. C. F., Geisow, M. J., Oatley, S. J., Rérat, B., and Rérat, C. (1978) J. Mol. Biol. 121, 339-356
5. Hamilton, J. A., Steinrauf, L. K., Braden, B. C., Liepnieks, J., Benson, M. D., Holmgren, G., Sandgren, O., and Steen, L. (1993) J. Biol. Chem. 268, 2416-2424
6. Terry, C. J., Damas, A. M., Oliveira, P., Saraiva, M. J. M., Alves, I. L., Costa, P. P., Matias, P. M., Sakaki, Y., and Blake, C. C. F. (1993) EMBO J. 12, 735-741
7. Sebastiāo, M. P., Saraiva, M. J., and Damas, A. M. (1998) J. Biol. Chem. 273, 24715-24722
8. Gustavsson, Å., Engström, U., and Westermark, P. (1990) Biochem. Biophys. Res. Commun. 175, 1159-1164
9. Colon, W., and Kelly, J. W. (1992) Biochemistry 31, 8654-8660
10. Lai, Z., Colón, W., and Kelly, J. W. (1996) Biochemistry 35, 6470-8482
11. Adams, D., and Said, G. (1996) J. Neurol. 243, 73-76
12. Furuya, H., Saraiva, M. J. M., Gawinowicz, M. A., Alves, I. L., Costa, P. P., Sasaki, H., Goto, I., and Sakaki, Y. (1991) Biochemistry 30, 2415-2421
13. Almeida, M. R., Damas, A. M., Lans, M. C., Brouwer, A., and Saraiva, M. J. M. (1997) Endocrine 6, 309-315
14. Van Jaarsveld, P. P., Edelhoch, H., Goodman, D. S., and Robbins, J. (1973) J. Biol. Chem. 248, 4698-4705
15. Nichols, A., Sharp, K. A., and Honig, B. (1991) Proteins Struct. Funct. Genet. 11, 281-296
16. Quintas, A., Saraiva, M. J., and Brito, R. M. M. (1997) FEBS Lett. 418, 297-300
17. McCutchen, S. L., Lai, Z., Miroy, G. J., Kelly, J. W., and Colón, W. (1995) Biochemistry 34, 13527-13536
18. Goldsteins, G., Andersson, K., Olofsson, A., Dacklin, I., Edvisson, Å., Baranov, V., Sandgren, O., Thylen, C., Hammarström, S., and Lundgren, E. (1997) Biochemistry 36, 5346-5352
19. Lashuel, H. A., Lai, Z., and Kelly, J. (1998) Biochemistry 37, 17851-17864
20. Eftink, M. R., and Ghiron, C. A. (1976) Biochemistry 15, 672-680
21. Lehrer, S. S., and Leavis, P. C. (1978) Methods Enzymol. 49, 222-236
22. Stryer, L. (1968) Science 162, 526-533
23. Miranker, A. D., and Dobson C. (1996) Curr. Opin. Struct. Biol. 6, 31-42
24. Cheng, S. Y., Pages, R. A., Saroff, H. A., Edelhoch, H., and Robbins, J. (1977) Biochemistry 16, 3707-3713
25. Inouye, H., Domingues, F. S., Damas, A. M., Saraiva, M. J., Lundgren, E., Sandgren, O., and Kirschner, D. A. (1998) Amyloid 5, 163-174
26. MeCutchen, S. L., Colón, W., and Kelly, J. W. (1993) Biochemistry 32, 12119-12127
27. Alves, I. L., Hayes, T. M., and Saraiva, M. J. M. (1997) Eur. J. Biochem. 249, 662-668