The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution

FEBS Letters

Volumn 418, Issue 3, 1997, Pages 297-300

  Quintas, Alexandre ^a,b   Saraiva, M J M ^c   Brito, Rui M M ^b,d  

^a INSTITUTO SUPERIOR DE CIÊNCIAS DA SAÚDE EGAS MONIZ   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Amyloid; Amyloidogenesis; Amyloidosis; Familial amyloidotic polyneuropathy; Gel filtration chromatography; Protein stability; Transthyretin

Indexed keywords

PREALBUMIN; RECOMBINANT PROTEIN;

AMYLOIDOSIS; ARTICLE; GEL FILTRATION CHROMATOGRAPHY; HUMAN; MUTATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN VARIANT;

AMYLOID; ESCHERICHIA COLI; PREALBUMIN; PROTEIN CONFORMATION; RECOMBINANT PROTEINS;

EID: 0030694782     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)01398-7     Document Type: Article

References (18)

1. Andrade, C. (1952) Brain 75, 408-427.
2. Saraiva, M.J.M. (1996) J. Periph. Nerv. Syst. 1, 179-188.
3. Jacobson, D.R., McFarlin, D.E., Kane, I. and Buxbaum, J.N. (1992) Hum. Genet. 89, 353-356.
4. Harrison, H.H., Gordon, G.D., Nichols, W.C. and Benson, M.D. (1991) Am. J. Med. Genet. 39, 442-452.
5. Alves, I.L., Altland, K., Almeida, M.R., Winter, P. and Saraiva, M.J.M. (1997) Hum. Mutat. 9, 226-233.
6. Coelho, T., Chorão, R., Sousa, A., Alves, I., Torres, M.F. and Saraiva, M.J.M. (1996) Neuromusc. Disord. 6, 27-32.
7. Colon, W. and Kelly, J.W. (1992) Biochemistry 31, 8654-8660.
8. McCutchen, S.L., Lai, Z., Miroy, G.J., Kelly, J.W. and Colon, W. (1995) Biochemistry 34, 13527-13536.
9. Bonifácio, M.J., Sakaki, Y. and Saraiva, M.J.M. (1996) Biochim. Biophys. Acta 1365, 35-42.
10. Terry, C.J., Damas, A.M., Oliveira, P., Saraiva, M.J.M., Alves, I.L., Costa, P.P., Matias, P.M., Sakaki, Y. and Blake, C.C.F. (1993) EMBO J. 12, 735-741.
11. Hamilton, J.A., Steinrauf, L.K., Braden, B.C., Liepnieks, J., Benson, M.D., Holmgren, G., Sandgren, O. and Steen, L. (1993) J. Biol. Chem. 268, 2416-2424.
12. Sebastião, P., Dauter, Z., Saraiva, M.J. and Damas, A.M. (1996) Acta Crystallogr. D52, 566-568.
13. Andrews, P. (1964) Biochem. J. 91, 222-223.
14. Brito, R.M.M., Reddick, R., Bennett, G.N., Rudolph, F.B. and Rosevear, P.R. (1990) Biochemistry 29, 9825-9831.
15. Furuya, H., Saraiva, M.J.M., Gawinowicz, M.A., Alves, I.L., Costa, P.P., Sasaki, H., Goto, I. and Sakaki, Y. (1991) Biochemistry 30, 2415-2421.
16. Almeida, M.R., Damas, A.M., Lans, M.C., Brouwer, A. and Saraiva, M.J.M. (1997) Endocrine 6, 309-315.
17. Van Jaarsveld, P.P., Edelhoch, H., Goodman, D.S. and Robbins, J. (1973) J. Biol. Chem. 548, 4698-4705.
18. Alves, I.L., Hays, M.T. and Saraiva, M.J.M. (1997) Eur. J. Biochem. (in press).