Basal phosphorylation of μ opioid receptor is agonist modulated and Ca2+-dependent

FEBS Letters

Volumn 387, Issue 1, 1996, Pages 53-57

  Wang, Zaijie ^a   Arden, James ^a   Sadée, Wolfgang ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Ca2+ dependent kinase; Mu opioid receptor; Narcotic dependence and tolerance; Receptor phosphorylation

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; CALCIUM; MORPHINE; MU OPIATE RECEPTOR; N (2 METHYLAMINOETHYL) 5 ISOQUINOLINESULFONAMIDE;

ARTICLE; CELL LINE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CELL; MORPHINE TOLERANCE; NARCOTIC DEPENDENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; STIMULATION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CELL LINE; ENZYME INHIBITORS; HUMANS; ISOQUINOLINES; MORPHINE; PHOSPHORYLATION; PIPERAZINES; PROTEIN KINASE C; RATS; RECEPTORS, OPIOID, MU;

EID: 0030007027     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(96)00467-X     Document Type: Article

References (18)

1. Arden, J.R., Segredo, V., Wang, Z., Lameh, J. and Sadée, W. (1995) J. Neurochem. 65, 1636-1645.
2. Wang, J.B., Pei, G. and Uhl, G.R. (1995) Soc. Neurosci. Abstr. 21, 1357.
3. Patterson, T.A., Appleyard, S.M. and Chavkin, C. (1995) Soc. Neurosci. Abstr. 21, 1356.
4. Pei, G., Samana, P., Lohse, M., Wang, M., Codina, J. and Lefkowitz, R.J. (1994) Proc. Natl. Acad. Sci. USA 91, 2699-2702.
5. Westphal, R.S., Backstrom, J.R. and Sanders-Bush, E. (1995) Mol. Pharmacol. 48, 200-205.
6. Wang, Z., Bilsky, E., Porreca, F. and Sadée, W. (1994) Life Sci. 54, PL339-350.
7. Bilsky, E.J., Bernstein, R.N., Wang, Z., Sadée, W. and Porreca, F. (1996) J. Pharmacol. Exp. Ther. (in press).
8. Chen, Y., Mestek, A., Liu, J., Hurley, J.A. and Yu, L. (1993) Mol. Pharmacol. 44, 8-12.
9. Lefkowitz, R.J. (1993) Cell 74, 409-412.
10. Haga, T., Haga, K. and Kameyama, K. (1994) J. Neurochem. 63, 400-412.
11. Hanks, S.K., Quinn, A.M. and Hunter, T. (1988) Science 241, 42-52.
12. Aloyo, V.J. (1995) Biochem. Pharmacol. 49, 17-21.
13. Shi, W., Osawa, S., Dickerson, C.D. and Weiss, E.R. (1995) J. Biol. Chem. 270, 2112-2119.
14. Kameyama, K., Haga, K., Moro, O. and Sadée, W. (1994) Europ. J. Biochem. 226, 26-276.
15. Sadée, W., Wang, Z., Arden, J.R. and Segredo, V. (1994) Analgesia 1, 11-14.
16. Akers, R.F., Lovinger, D.M., Colley, P.A., Linden, D.J. and Routtenberg, A. (1986) Science 231, 587-589.
17. Klann, E., Chen, S.-J. and Sweatt, J.D. (1993) Proc. Natl. Acad. Sci. USA 90, 8337-8341.
18. Meyer, T., Hanson, P.I., Stryer, L. and Schulman, H. (1992) Science 256, 1199-120.