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Volumn 68, Issue 6, 1997, Pages 2395-2404

A constitutively internalizing and recycling mutant of the μ-opioid receptor

Author keywords

Agonist induced internalization; Clathrin coated vesicles; Constitutive recycling; Transferrin receptor; Opioid receptor

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MU OPIATE RECEPTOR;

EID: 0030953290     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.68062395.x     Document Type: Article
Times cited : (71)

References (35)
  • 1
    • 0026545612 scopus 로고
    • Potocytosis: Sequestration and transport of small molecules by caveolae
    • Anderson R. G., Kamen B. A., Rothberg K. G., and Lacey S.W. (1992) Potocytosis: sequestration and transport of small molecules by caveolae. Science 255, 410-411.
    • (1992) Science , vol.255 , pp. 410-411
    • Anderson, R.G.1    Kamen, B.A.2    Rothberg, K.G.3    Lacey, S.W.4
  • 2
    • 0029130047 scopus 로고
    • Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged μ-opioid receptor expressed in HEK 293 cells
    • Arden J. R., Segredo V., Wang Z., Lameh J., and Sadée W. (1995) Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged μ-opioid receptor expressed in HEK 293 cells. J. Neurochem. 65, 1636-1645.
    • (1995) J. Neurochem. , vol.65 , pp. 1636-1645
    • Arden, J.R.1    Segredo, V.2    Wang, Z.3    Lameh, J.4    Sadée, W.5
  • 3
    • 0028000662 scopus 로고
    • A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated β2-adrenergic receptor sequestration
    • Barak L. S., Tiberi M., Freedman N. J., Kwarta M. M., Lefkowitz R. J. and Caron M. G. (1994) A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated β2-adrenergic receptor sequestration. J. Biol. Chem. 269, 2790-2795.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2790-2795
    • Barak, L.S.1    Tiberi, M.2    Freedman, N.J.3    Kwarta, M.M.4    Lefkowitz, R.J.5    Caron, M.G.6
  • 4
    • 0027239858 scopus 로고
    • Serines and threonines in the gastrin-releasing peptide receptor carboxyl terminus mediate internalization
    • Benya R. V., Fathi Z., Battey J. F., and Jensen R. T. (1993) Serines and threonines in the gastrin-releasing peptide receptor carboxyl terminus mediate internalization. J. Biol. Chem. 268, 20285-20290.
    • (1993) J. Biol. Chem. , vol.268 , pp. 20285-20290
    • Benya, R.V.1    Fathi, Z.2    Battey, J.F.3    Jensen, R.T.4
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 6
    • 0028987445 scopus 로고
    • Coupling of muscarinic m1, m2 and m3 acetylcholine receptors, expressed in Chinese hamster ovary cells, to pertussis toxin-sensitive/ insensitive guanine nucleotide-binding proteins
    • Burford N. T., Tobin A. B., and Nahorski S. R. (1995) Coupling of muscarinic m1, m2 and m3 acetylcholine receptors, expressed in Chinese hamster ovary cells, to pertussis toxin-sensitive/ insensitive guanine nucleotide-binding proteins. Eur. J. Pharmacol. 289, 343-351.
    • (1995) Eur. J. Pharmacol. , vol.289 , pp. 343-351
    • Burford, N.T.1    Tobin, A.B.2    Nahorski, S.R.3
  • 7
    • 0025959676 scopus 로고
    • Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration
    • Campbell P. T., Hnatowich M., O'Dowd B. F., Caron M. G., Letkowitz R. J., and Hausdorff W. P. (1991) Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration. Mol. Pharmacol. 39, 192-198.
    • (1991) Mol. Pharmacol. , vol.39 , pp. 192-198
    • Campbell, P.T.1    Hnatowich, M.2    O'Dowd, B.F.3    Caron, M.G.4    Letkowitz, R.J.5    Hausdorff, W.P.6
  • 8
    • 0028878813 scopus 로고
    • Thr-422 and Tyr-424 residues in the carboxyl terminus are critical for the internalization of the rat neurotensin receptor
    • Chabry J., Botto J. M., Nouel D., Beaudet A., Vincent J. P., and Mazella J. (1995) Thr-422 and Tyr-424 residues in the carboxyl terminus are critical for the internalization of the rat neurotensin receptor. J. Biol. Chem. 270, 2439-2442.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2439-2442
    • Chabry, J.1    Botto, J.M.2    Nouel, D.3    Beaudet, A.4    Vincent, J.P.5    Mazella, J.6
  • 10
    • 0027202213 scopus 로고
    • Molecular cloning and functional expression of a μ-opioid receptor from rat brain
    • Chen Y., Mestek A., Liu J., Hurley J. A., and Yu L. (1993) Molecular cloning and functional expression of a μ-opioid receptor from rat brain. Mol. Pharmacol. 44, 8-12.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 8-12
    • Chen, Y.1    Mestek, A.2    Liu, J.3    Hurley, J.A.4    Yu, L.5
  • 11
    • 0025316096 scopus 로고
    • Separation of the structural requirements for agonist-promoted activation and sequestration of the beta-adrenergic receptor
    • Cheung A. H., Dixon R. A., Hill W. S., Sigal I. S., and Strader C. D. (1990) Separation of the structural requirements for agonist-promoted activation and sequestration of the beta-adrenergic receptor. Mol. Pharmacol. 37, 775-779.
    • (1990) Mol. Pharmacol. , vol.37 , pp. 775-779
    • Cheung, A.H.1    Dixon, R.A.2    Hill, W.S.3    Sigal, I.S.4    Strader, C.D.5
  • 12
    • 0029134736 scopus 로고
    • Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin
    • Damke H., Baba T., van der Bliek A. M., and Schmid S. L. (1995) Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin. J. Cell Biol. 131, 69-80.
    • (1995) J. Cell Biol. , vol.131 , pp. 69-80
    • Damke, H.1    Baba, T.2    Van Der Bliek, A.M.3    Schmid, S.L.4
  • 13
    • 0022340784 scopus 로고
    • Inhibition of receptor-mediated but not fluid-phase endocytosis in polymorphonuclear leukocytes
    • Daukas G. and Zigmond S. H. (1985) Inhibition of receptor-mediated but not fluid-phase endocytosis in polymorphonuclear leukocytes. J. Cell Biol. 101, 1673-1679.
    • (1985) J. Cell Biol. , vol.101 , pp. 1673-1679
    • Daukas, G.1    Zigmond, S.H.2
  • 14
    • 0028988023 scopus 로고
    • Agonist regulation of alpha 1B-adrenergic receptor subcellular distribution and function
    • Fonseca M. I., Button D. C., and Brown R. D. (1995) Agonist regulation of alpha 1B-adrenergic receptor subcellular distribution and function. J. Biol. Chem. 270, 8902-8909.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8902-8909
    • Fonseca, M.I.1    Button, D.C.2    Brown, R.D.3
  • 16
    • 0024999554 scopus 로고
    • A truncation mutation in the avian beta-adrenergic receptor causes agonist-induced internalization and GTP-sensitive agonist binding characteristic of mammalian receptors
    • Hertel C., Nunnally M. H., Wong S. K., Murphy E. A., Ross E. M., and Perkins J. P. (1990) A truncation mutation in the avian beta-adrenergic receptor causes agonist-induced internalization and GTP-sensitive agonist binding characteristic of mammalian receptors. J. Biol. Chem. 265, 17988-17994.
    • (1990) J. Biol. Chem. , vol.265 , pp. 17988-17994
    • Hertel, C.1    Nunnally, M.H.2    Wong, S.K.3    Murphy, E.A.4    Ross, E.M.5    Perkins, J.P.6
  • 17
    • 0024595608 scopus 로고
    • Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation
    • Heuser J. E. and Anderson R. G. (1989) Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. J. Cell Biol. 108, 389-400.
    • (1989) J. Cell Biol. , vol.108 , pp. 389-400
    • Heuser, J.E.1    Anderson, R.G.2
  • 18
    • 0028944574 scopus 로고
    • Activating and inactivating mutations in N- and C-termmal i3 loop junctions of muscarinic acetylcholine Hm1 receptors
    • Högger P., Shockley M. S., Lameh J., and Sadée W. (1995) Activating and inactivating mutations in N-and C-termmal i3 loop junctions of muscarinic acetylcholine Hm1 receptors. J. Biol. Chem. 270, 7405-7410.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7405-7410
    • Högger, P.1    Shockley, M.S.2    Lameh, J.3    Sadée, W.4
  • 19
    • 0028840145 scopus 로고
    • The cytoplasmic tail of the G-protein-coupled receptor for parathyroid hormone and parathyroid hormone-related protein contains positive and negative signals for endocytosis
    • Huang Z., Chen Y., and Nissenson R. A. (1995) The cytoplasmic tail of the G-protein-coupled receptor for parathyroid hormone and parathyroid hormone-related protein contains positive and negative signals for endocytosis. J. Biol. Chem. 270, 151-156.
    • (1995) J. Biol. Chem. , vol.270 , pp. 151-156
    • Huang, Z.1    Chen, Y.2    Nissenson, R.A.3
  • 21
    • 0029670965 scopus 로고    scopus 로고
    • The tyrosine within the NPXnY motif of the human angiotensin II type 1 receptors is involved in mediating signal transduction but not essential for internalization
    • Laporte S. A., Servanr G., Richard D. E., Escher E., Guillemette G., and Leduc R. (1996) The tyrosine within the NPXnY motif of the human angiotensin II type 1 receptors is involved in mediating signal transduction but not essential for internalization. Mol. Pharmacol. 49, 89-95.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 89-95
    • Laporte, S.A.1    Servanr, G.2    Richard, D.E.3    Escher, E.4    Guillemette, G.5    Leduc, R.6
  • 23
    • 0028270707 scopus 로고
    • Overlapping multi-site domains of the muscarinic cholinergic Hm1 receptor involved in signal transduction and sequestration
    • Moro O., Shockley M. S., Lameh J., and Sadée W. (1994) Overlapping multi-site domains of the muscarinic cholinergic Hm1 receptor involved in signal transduction and sequestration. J. Biol. Chem. 269, 6651-6655.
    • (1994) J. Biol. Chem. , vol.269 , pp. 6651-6655
    • Moro, O.1    Shockley, M.S.2    Lameh, J.3    Sadée, W.4
  • 25
    • 0025303751 scopus 로고
    • Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate
    • Rothberg K. G., Ying Y.-S., Kamen B. A., and Anderson R. G. W. (1990a) Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate. J. Cell Biol. 110, 637-649.
    • (1990) J. Cell Biol. , vol.110 , pp. 637-649
    • Rothberg, K.G.1    Ying, Y.-S.2    Kamen, B.A.3    Anderson, R.G.W.4
  • 26
    • 0025695634 scopus 로고
    • The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin coated pit endocytic pathway
    • Rothberg K. G., Ying Y.-S., Kolhouse J. F., and Anderson R. G. W. (1990b) The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin coated pit endocytic pathway. J. Cell Biol. 111, 2931-2938.
    • (1990) J. Cell Biol. , vol.111 , pp. 2931-2938
    • Rothberg, K.G.1    Ying, Y.-S.2    Kolhouse, J.F.3    Anderson, R.G.W.4
  • 27
    • 0023582912 scopus 로고
    • Acidification of the cytosol inhibits endocytosis from coated pits
    • Sandvig K., Olsnes S., Petersen O., and van Deurs B. (1987) Acidification of the cytosol inhibits endocytosis from coated pits. J. Cell Biol. 105, 679-689.
    • (1987) J. Cell Biol. , vol.105 , pp. 679-689
    • Sandvig, K.1    Olsnes, S.2    Petersen, O.3    Van Deurs, B.4
  • 28
    • 0027999250 scopus 로고
    • Double-label immunofluorescence with the laser scanning confocal microscope using cyanine dyes
    • Sargent P. B. (1994) Double-label immunofluorescence with the laser scanning confocal microscope using cyanine dyes. Neuroimage 1, 288-295.
    • (1994) Neuroimage , vol.1 , pp. 288-295
    • Sargent, P.B.1
  • 29
    • 0030061672 scopus 로고    scopus 로고
    • Muscarinic receptor sequestration in SH-SY5Y neuroblastoma cells is inhibited when clathrin distribution is perturbed
    • Slowiejko D. M., McEwen E. L., Ernst S. A., and Fisher S. K. (1996) Muscarinic receptor sequestration in SH-SY5Y neuroblastoma cells is inhibited when clathrin distribution is perturbed. J. Neurochem. 66, 186-196.
    • (1996) J. Neurochem. , vol.66 , pp. 186-196
    • Slowiejko, D.M.1    McEwen, E.L.2    Ernst, S.A.3    Fisher, S.K.4
  • 30
    • 0028889191 scopus 로고
    • Stable expression of a truncated AT1A receptor in CHO-K1 cells. The carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization
    • Thomas W. G., Thekkumkara T. J., Motel T. J., and Baker K. M. (1995) Stable expression of a truncated AT1A receptor in CHO-K1 cells. The carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization. J. Biol. Chem. 270, 207-213.
    • (1995) J. Biol. Chem. , vol.270 , pp. 207-213
    • Thomas, W.G.1    Thekkumkara, T.J.2    Motel, T.J.3    Baker, K.M.4
  • 31
    • 0027504836 scopus 로고
    • Cloning and pharmacological characterization of a rat μ opioid receptor
    • Thompson R. C., Mansour A., Akil H., and Watson S. J., (1193) Cloning and pharmacological characterization of a rat μ opioid receptor. Neuron 11, 903-913.
    • (1193) Neuron , vol.11 , pp. 903-913
    • Thompson, R.C.1    Mansour, A.2    Akil, H.3    Watson, S.J.4
  • 32
    • 0027335690 scopus 로고
    • Precoupling of Gi/G(o)-linked receptors and its allosteric regulation by monovalent cations
    • Tian W. N. and Deth R. C. (1993) Precoupling of Gi/G(o)-linked receptors and its allosteric regulation by monovalent cations. Life Sci. 52, 1899-1907.
    • (1993) Life Sci. , vol.52 , pp. 1899-1907
    • Tian, W.N.1    Deth, R.C.2
  • 33
    • 0030035551 scopus 로고    scopus 로고
    • Human muscarinic cholinergic receptor Hm1 internalizes via clathrin-coated vesicles
    • Tolbert L. M. and Lameh J. (1996) Human muscarinic cholinergic receptor Hm1 internalizes via clathrin-coated vesicles. J. Biol. Chem. 271, 17335-17342.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17335-17342
    • Tolbert, L.M.1    Lameh, J.2
  • 34
    • 0029825797 scopus 로고    scopus 로고
    • Sequestration of the delta opioid receptor. Role of the C terminus in agonist-mediated internalization
    • Trapaidze N., Keith D.E., Cvejic S., Evans C.J., and Devi L.A. (1996) Sequestration of the delta opioid receptor. Role of the C terminus in agonist-mediated internalization. J. Biol. Chem. 271, 29279-29285.
    • (1996) J. Biol. Chem. , vol.271 , pp. 29279-29285
    • Trapaidze, N.1    Keith, D.E.2    Cvejic, S.3    Evans, C.J.4    Devi, L.A.5
  • 35
    • 0028238350 scopus 로고
    • Antagonist-dependent and -independent steps in the mechanism of adrenergic receptor internalization
    • von Zastrow M. Kobilka B. K. (1994) Antagonist-dependent and -independent steps in the mechanism of adrenergic receptor internalization. J. Biol. Chem. 269, 18448-18452.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18448-18452
    • Von Zastrow, M.1    Kobilka, B.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.