Site-directed mutagenesis but not γ-carboxylation of Glu-35 in factor VIIa affects the association with tissue factor

FEBS Letters

Volumn 385, Issue 3, 1996, Pages 241-243

  Persson, Egon ^a   Nielsen, Lars S ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

Factor VIIa; Gla domain; Gla mutation; Surface plasmon resonance; Tissue factor binding; carboxylation

Indexed keywords

BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 9; PROTEIN C; PROTHROMBIN; THROMBOPLASTIN;

AMINO ACID SEQUENCE; ARTICLE; HUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS;

1-CARBOXYGLUTAMIC ACID; ANIMALS; BASE SEQUENCE; BINDING SITES; CALCIUM; CRICETINAE; DNA PRIMERS; FACTOR VIIA; GLUTAMIC ACID; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; THROMBOPLASTIN;

EID: 0029951107     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(96)00400-0     Document Type: Article

References (22)

1. Furie, B. and Furie, B.C. (1988) Cell 53, 505-518.
2. O'Hara, P.J., Grant, F.J., Haldeman, B.A., Gray, C.L., Insley, M.Y., Hagen, F.S. and Murray, M.J. (1987) Proc. Natl. Acad. Sci. USA 84, 5158-5162.
3. Soriano-Garcia, M., Padmanabhan, K., de Vos, A.M. and Tulinsky, A. (1992) Biochemistry 31, 2554-2566.
4. Banner, D.W., D'Arcy, A., Chène, C., Winkler, F.K., Guha, A., Konigsberg, W.H., Nemerson, Y. and Kirchhofer, D. (1996) Nature 380, 41-46.
5. Sunnerhagen, M., Forsén, S., Hoffrén, A.-M., Drakenberg, T., Teleman, O. and Stenflo, J. (1995) Nat. Struct. Biol. 2, 504-509.
6. Berkner, K.L., Walker, K., King, J. and Kumar, A.A. (1989) Thromb. Haemost. 62, 345.
7. Zhang, L., Jhingan, A. and Castellino, F.J. (1992) Blood 80, 942-952.
8. Zhang, L. and Castellino, F.J. (1992) J. Biol. Chem. 267, 26078-26084.
9. Zhang, L. and Castellino, F.J. (1993) J. Biol. Chem. 268, 12040-12045.
10. Christiansen, W.T., Tulinsky, A. and Castellino, F.J. (1994) Biochemistry 33, 14993-15000.
11. Ratcliffe, J.V., Furie, B. and Furie, B.C. (1993) J. Biol. Chem. 268, 24339-24345.
12. Thim, L., Bjoern, S., Christensen, M., Nicolaisen, E.M., Lund-Hansen, T., Pedersen, A. and Hedner, U. (1988) Biochemistry 27, 7785-7793.
13. Bond, M.D., Patel, H., Huberty, M.C., Jankowski, M.A., Scoble, H.A., Switzer, M. and Foster, W.B. (1995) Thromb. Haemost. 73, 1205.
14. Persson, E. and Petersen, L.C. (1995) Eur. J. Biochem. 234, 293-300.
15. Laemmli, U.K. (1970) Nature 227, 680-685.
16. Hagen, F.S., Gray, C.L., O'Hara, P., Grant, F.J., Saari, G.C., Kurachi, K. and Davie, E.W. (1986) Proc. Natl. Acad. Sci. USA 83, 2412-2416.
17. Sanger, F., Nicklen, S. and Coulsen, A.R. (1977) Proc. Natl. Acad. Sci. USA 74, 5463-5467.
18. Busby, S.J., Mulvihill, E., Rao, D., Kumar, A.A., Lioubin P., Heipel, M., Sprecher, C., Halfpap, L., Prunkard, D., Gambee, J. and Foster, D.C. (1991) J. Biol. Chem. 266, 15286-15292.
19. Ho, S.N., Hunt, H.D., Horton, R.M., Pullen, J.K. and Pease, L.R. (1989) Gene 77, 51-59.
20. Gorman, C.M. (1985) in: DNA Cloning. A Practical Approach, vol. 1-2 (Glover, D.M. ed.) IRL Press, Oxford.
21. Persson, E. (1996) Haemostasis 26 (Suppl. 1), 31-34.
22. Cheung, W.-F. and Stafford, D.W. (1995) Thromb. Res. 79, 199-206.