Regulation of p42/p44 mitogen-activated protein kinase by the human adenosine A3 receptor in transfected CHO cells

European Journal of Pharmacology

Volumn 420, Issue 1, 2001, Pages 19-26

  Graham, Stuart ^a   Combes, Patricia ^a   Crumiere, Magali ^a   Klotz, Karl Norbert ^b   Dickenson, John M ^a  

^a NOTTINGHAM TRENT UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Adenosine A3 receptor; c fos Promoter; CHO (chinese hamster ovary) cell; MAD (mitogen activated protein) kinase

Indexed keywords

1 DEOXY 1 [6 [[[(3 IODOPHENYL)METHYL]AMINO] 9H PURIN 9 YL] N METHYL BETA DEXTRO RIBOFURANURONAMIDE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE A3 RECEPTOR; CHELERYTHRINE; COMPLEMENTARY DNA; CYCLIC AMP; DAIDZEIN; FORSKOLIN; FURAN DERIVATIVE; GENISTEIN; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME REGULATION; GENE EXPRESSION; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; REPORTER GENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOSINE; ANDROSTADIENES; ANIMALS; CHO CELLS; CHROMONES; CRICETINAE; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; FORSKOLIN; HUMANS; LUCIFERASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MORPHOLINES; PHOSPHORYLATION; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; RECOMBINANT FUSION PROTEINS;

EID: 0035908039     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00976-1     Document Type: Article

References (38)

1. G-protein dependent activation of phospholipase C by adenosine A3 receptors in rat brain
2. Genistein, a specific inhibitor of tyrosine specific protein kinases
3. 2+-ionophore-induced secretion in a rat mast cell line
4. 3 receptors mediate mitogen-activated protein kinase activation via a phosphatidylinositol 3-kinase and an atypical protein kinase C-dependent mechanism
5. Potent selective inhibitors of protein kinase C
6. 2-purinoceptor-mediated activation of the mitogen-activated protein kinase cascade in transfected CHO cells
7. Influence of rolipram on the cyclic 3′,5′-adenine monophosphate response to histamine and adenosine in slices of guinea-pig cerebral cortex
8. A synthetic inhibitor of the mitogen-activated protein kinase cascade
9. 2B receptor-mediated interleukin-8 production in human mast cells
10. 3 receptors mediate hypotension in the angiotension II supported circulation of the pithes rat
11. 1A receptor via a G protein βγ subunit initiated pathway
12. q-mediated mitogen activated protein kinase activation
13. Phosphatidylinositol 3-kinase is an early intermediate in the Gβγ-mediated mitogen-activated protein kinase signaling pathway
14. Cherlerythrine is a potent and specific inhibitor of protein kinase C.
15. The regulation of AP-1 activity by mitogen-activated protein kinases
16. Comparative pharmacology of human adenosine receptor subtypes - Characterization of stably transfected receptors in CHO cells
17. 3 adenosine receptors
18. ras
19. Signal transduction through MAP kinase cascades
20. Signaling from G-protein coupled receptors to mitogen-activated protein (MAP) kinase cascades
21. Protein measurements with the folin phenol reagent
22. 3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart
23. Role of c-Src tyrosine kinase in G-protein coupled receptor and Gβγ subunit mediated activation of mitogen-activated protein kinases
24. Selective inhibition of protein kinase C isozymes by the indolcarbazole Gö
25. 3 receptor
26. 3 adenosine receptor
27. Sustained activation of p42/p44 mitogen-activated protein kinase during recovery from simulated ischaemia mediates adaptive cytoprotection in cardiomyocytes
28. Receptors for purines and pyrimidines
29. 3R is the unique adenosine receptor which facilitates release of allergic mediators in mast cells
30. 1MF-2 cells
31. 3 receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2
32. 2A adenosine receptor via a rap1-dependent and via a p21ras-dependent pathway
33. 2A adenosine receptor in primary human endothelial cells
34. Regulation of the ERK subgroup of MAP kinase cascades through G protein coupled receptors
35. PI 3-kinase gamma and protein kinase C-zeta mediate Ras-independent activation of MAP kinase by a G(i) protein coupled receptor
36. Protein kinases as mediators of phosphoinositide 3-kinase signaling
37. Mitogenic signaling via G-protein coupled receptors
38. Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human