Growth inhibitory effect of green tea extract and (-)-epigallocatechin in Ehrlich ascites tumor cells involves a cellular thiol-dependent activation of mitogenic-activated protein kinases

Chemico-Biological Interactions

Volumn 134, Issue 2, 2001, Pages 113-133

  Opare Kennedy, David ^a   Kojima, Akiko ^a   Hasuma, Tadayoshi ^b   Yano, Yoshihisa ^b   Otani, Shuzo ^b   Matsui Yuasa, Isao ^a  

^a Osaka Prefecture University   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

( ) Epigallocatechin; Ehrlich ascites tumor cells; ERK 1 2 MAPK; Glutathione; Green tea; JNK SAPK; p38 MAPK; Protein sulfhydryl

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; EPIGALLOCATECHIN; MITOGEN ACTIVATED PROTEIN KINASE; PLANT EXTRACT; POLYPHENOL DERIVATIVE; SYNAPTOPHYSIN; THIOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASCITES TUMOR CELL; CELL VIABILITY; CONCENTRATION RESPONSE; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; EHRLICH ASCITES TUMOR CELL; ENZYME ACTIVITY; MALE; NONHUMAN; RAT; STIMULATION; TEA;

ACETYLCYSTEINE; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, EHRLICH TUMOR; CATECHIN; CELL DIVISION; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; KINETICS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; POLYMERS; SULFHYDRYL COMPOUNDS; TEA; TUMOR CELLS, CULTURED;

EID: 0035897081     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(00)00251-9     Document Type: Article

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