Developmental expression of the fragile X-related 1 proteins in mouse testis: Association with microtubule elements

Human Molecular Genetics

Volumn 10, Issue 24, 2001, Pages 2803-2811

  Huot, Marc Etienne ^a   Mazroui, Rachid ^a   Leclerc, Pierre ^a,b   Khandjian, Edouard W ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; MESSENGER RNA; RNA BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; ELECTRON MICROSCOPY; FRAGILE X SYNDROME; IMMUNOHISTOCHEMISTRY; MALE; MENTAL RETARDATION MALFORMATION SYNDROME; MICROTUBULE; MOUSE; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SPLICING; RNA TRANSPORT; SPERMATOGENESIS; TESTIS DEVELOPMENT; TISSUE SPECIFICITY;

ANIMALIA; MAMMALIA;

EID: 0035891843     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/10.24.2803     Document Type: Article

References (64)

1. FMR1 and mutations in fragile X syndrome: Molecular biology, biochemistry and genetics
2. Biology of the fragile X mental retardation protein, an RNA-binding protein
3. FMR 1 gene and fragile X syndrome
4. Absence of expression of the FMR-1 gene in fragile X syndrome
5. Fragile sites on human chromosomes: Demonstration of their dependence on the type of tissue culture medium
6. Highly conserved 3′ UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1
7. The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2
8. The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein
9. FXR1, an autosomal homolog of the fragile X mental retardation gene
10. The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals
11. Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations
12. + mRNA in actively translating polyribosomes
13. FMRP associates with polyribosomes as an mRNP and the 1304N mutation of severe fragile X syndrome abolishes this association
14. Muscle specific fragile X related protein 1 isoforms are sequestered in the nucleus of undifferentiated myoblast
15. Evidence that fragile X mental retardation protein is a negative regulator of translation
16. The fragile X mental retardation protein inhibits translation via interacting with mRNA
17. Immunocytochemical and biochemical characterization of FMRP, FXR1P and FXR2P in the mouse
18. Immunocytochemical characterization of FMRP, FXR1P and FXR2P during embryonic development in the mouse
19. Novel isoforms of the fragile X related protein FXR1P are expressed during myogenesis
20. Alternative splicing in the murine and human FXR1 genes
21. Spermatogenic cells of the prepuberal mouse. Isolation and morphological characterization
22. Preparation of spermagonia, spermatocytes and round spermatids for analysis of gene expression using fluorescence-activated cell sorting
23. Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes
24. Interactional cloning of the 84-kDa major outer dense fiber protein Odf84
25. Reversible assembly purification of microtubules without assembly-promoting agents and further purification of tubulin, microtubule-associated proteins and MAP fragments
26. The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation
27. Gene expression during mammalian meiosis
28. The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins
29. Spnr, a murine RNA-binding protein that is localized to cytoplasmic microtubules
30. Spermatid perinuclear ribonucleic acid-binding protein binds microtubules in vitro and associates with abnormal manchettes in vivo in mice
31. Transport between the cell nucleus and the cytoplasm
32. Transport of proteins and RNA in and out of the nucleus
33. Nucleocytoplasmic trafficking of proteins with or without Ran?
34. A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with the FMRP-related proteins FXR1P and FXR2P
35. p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase
36. G proteins and small GTPases: Distant relatives keep in touch
37. Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons
38. Staufen protein associates with the 3′ UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner
39. Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dentritic transport in living hippocampal neurons
40. Mammalian Staufen is a double-stranded RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum
41. Two rat brain staufen isoforms differentially bind RNA
42. A testis cytoplasmic RNA-binding protein that has the properties of translational repressor
43. A novel gene, translin, encodes a recombinantion hotspot binding protein associated with chromosomal translocations
44. Testis/brain RNA-binding protein attaches translationally repressed and transported mRNAs to microtubules
45. The RNA-binding protein, TB-RBP, is the mouse homologue of translin, a recombination protein associated with chromosomal translocations
46. The DNA/RNA-binding protein, TB-RBP, moves from the nucleus to the cytoplasm and through intercellular bridges in male germ cells
47. mRNA and cytoskeletal filaments
48. Molecular insights into mRNA transport and local translation in the mammalian nervous system
49. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
50. Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic and sperm morphological abnormalities
51. The roles of RNA-binding proteins in spermatogenesis and male infertility
52. Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them
53. Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex
54. Metabotropic glutamate receptors trigger postsynaptic protein synthesis
55. Abnormal dentritic spines in fragile X knockout mice: Maturation and pruning deficits
56. Abnormal development of dendritic spines in FMR1 knock-out mice
57. A heterogeneous set of FMR1 proteins is widely distributed in mouse tissues and is modulated in cell culture
58. Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a
59. A 56-54 kDa non grata signal in immunoblot analysis using the horseradish peroxidase-chemiluminescence system
60. The fragile X mental retardation protein is associated with ribosomes
61. UV crosslinking of RNA to nylon membrane enhances hybridization signals
62. Recovery, capacitation, acrosome reaction and fractionation of sperm