Role of CtBP in transcriptional repression by the Drosophila giant protein

Developmental Biology

Volumn 239, Issue 2, 2001, Pages 229-240

  Strunk, Bethany ^a   Struffi, Paolo ^a   Wright, Kevin ^a   Pabst, Brandon ^a   Thomas, Jelani ^a   Qin, Ling ^a   Arnosti, David N ^a  

^a Michigan State University   (United States)

Author keywords

CtBP; Even skipped; Giant; Kr ppel; Transcriptional repression

Indexed keywords

PROTEIN; PROTEIN CTBP; PROTEIN KRUPPEL; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BLASTODERM; CONSENSUS SEQUENCE; DROSOPHILA; DROSOPHILA HYDEI; ENHANCER REGION; EVOLUTION; GENE CONTROL; GENE EXPRESSION; IN SITU HYBRIDIZATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; TRANSGENE;

DROSOPHILA; GASTROPODA;

EID: 0035891067     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2001.0454     Document Type: Article

References (36)

1. The hardwiring of development: Organization and function of genomic regulatory systems
2. The eve stripe 2 enhancer employs multiple modes of transcriptional synergy
3. Molecular evolution in Drosophila and the higher Diptera II. A time scale for fly evolution
4. Long-range repression in the Drosophila embryo
5. The giant gene of Drosophila encodes a b-ZIP DNA-binding protein that regulates the expression of other gap genes
6. Groucho/TLE family proteins and transcriptional repression
7. The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster
8. DNA sequence-dependent folding determines the divergence in binding specificities between Maf and other bZIP proteins
9. Control by combinatorial codes
10. Short-range repression permits multiple enhancers to function autonomously within a complex promoter
11. Transcriptional repression by the Drosophila Giant protein: Cis element positioning provides an alternative means of interpreting an effector gradient
12. Cis-acting control elements for Krüppel expression in the Drosophila embryo
13. Gene expression mediated by cis-acting sequences of the Krüppel gene in response to the Drosophila morphogens bicoid and hunchback
14. Competition for overlapping sites in the regulatory region of the Drosophila gene Krüppel
15. Analysis of Krüppel control elements reveals that localized expression results from the interaction of multiple subelements
16. Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed
17. Structure and regulation of the fushi tarazu gene from Drosophila hydei
18. dCtBP-dependent and -independent repression activities of the Drosophila knirps protein
19. Mutually repressive interactions between the gap genes giant and Krüppel define middle body regions of the Drosophila embryo
20. Hairy stripe 7 element mediates activation and repression in response to different domains and levels of Krüppel in the Drosophila embryo
21. Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage
22. Functional analysis of eve stripe 2 enhancer evolution in Drosophila: Rules governing conservation and change
23. Evidence for stabilizing selection in a eukaryotic enhancer element
24. Rapid divergence in the course of Drosophila evolution reveals structural important domains of the Notch antagonist Hairless
25. Structural determinants present in the C-terminal binding protein binding site of adenovirus early region 1A proteins
26. Interaction of short-range repressors with Drosophila CtBP in the embryo
27. dCtBP mediates transcriptional repression by Knirps, Krüppel and Snail in the Drosophila embryo
28. Drosophila CtBP: A Hairy-interacting protein required for embryonic segmentation and Hairy-mediated transcriptional repression
29. Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene
30. Regulation of the even-skipped stripe 2 in the Drosophila embryo
31. Spacing ensures autonomous expression of different stripe enhancers in the even-skipped promoter
32. Regulation of a segmentation stripe by overlapping activators and repressors in the embryo
33. The zygotic control of Drosophila pair-rule gene expression. I. A search for new pair-rule regulatory loci
34. The gap protein giant uses distinct mechanisms for differential positioning of gene expression borders in the Drosophila embryo
35. Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo
36. Acetylation of adenovirus E1A regulates binding of the transcriptional core-pressor CtBP