Cytokines production of U5A2-13-positive T cells by stimulation with glycolipid α-galactosylceramide

European Journal of Immunology

Volumn 30, Issue 8, 2000, Pages 2138-2146

  Azuma, Masato ^a,b   Kato, Kazunori ^a   Ikarashi, Yoshinori ^a   Asada Mikami, Rumiko ^a   Maruoka, Hidenori ^c   Takaue, Yoichi ^d   Saito, Atsushi ^b   Wakasugi, Hiro ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

^d NATIONAL CANCER CENTER HOSPITAL   (Japan)

Author keywords

NK like T cell; NK1.1; U5A2 13 mAb

Indexed keywords

BETA 2 MICROGLOBULIN; CYTOKINE; GALACTOSYLCERAMIDE; GAMMA INTERFERON; GLYCOLIPID; INTERLEUKIN 4;

ANIMAL CELL; ARTICLE; CYTOKINE PRODUCTION; DENDRITIC CELL; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS; ANTIGENS, CD1; ANTIGENS, SURFACE; CYTOKINES; FEMALE; GALACTOSYLCERAMIDES; INTERLEUKIN-4; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LIVER; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PROTEINS;

EID: 0033849159     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(2000)30:8<2138::AID-IMMU2138>3.0.CO;2-Y     Document Type: Article

References (50)

1. + T cells
2. + T cell receptor-αβ+ cells: New clues to their origin, specificity, and function
3. Natural T cells: Cells that co-express NKRP-1 and TCR
4. Natural killer like T cells develop in SJL mice despite genetically distinct defects in NK1.1 expression and inducible interleukin-4 production
5. Establishment of monoclonal anti-NK-1.1 antibody
6. The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: The NK gene complex
7. -- T cells in mice and humans
8. + T cell antigen receptor α chain in mice
9. A novel population of T cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family
10. - single positive thymocyte subpopulation that express a highly skewed T cell antigen receptor V and number 61538; family
11. - cells produce IL-4
12. - thymocytes with specific lymphokine secretion
13. + T cells produce large amounts of IL-4 and IFN-γ upon activation by anti-CD3 or CD1
14. + cells upon NKR-P1 cross-linking
15. Agelasphins, novel α-galactosylceramides from the marine sponge Agelas Mauritianus
16. Agelasphins, novel antitumor and immunostimulatiory cerebrosides from the marine sponge Agelas Mauritianus
17. KRN7000, a novel immunomodulator, and its antitumor activities
18. Treatment of hepatic metastasis of the Colon26 adenocarcinoma with an α-galactosylceramide, KRN7000
19. Requirement for V and agr;14 NKT cells in IL-12-mediated rejection of tumors
20. CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3
21. - T cells in a TH2 response and in immuno-globulin E production
22. Activation of NK T cells by CD1d and α-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype
23. Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Vα14 natural killer T cells
24. Antitumor activities of combined treatment with a novel immunomodulator, (2S,3S,4R)-1-O-(α-D-galactopyranosyl)-2-(N-hexa-cosanoylamino) -1,3,4-octadec anetriol (KRN7000), and radiotherapy in tumor-bearing mice
25. + αβ T cells in IL-12 production during Salmonella infection
26. Natural Miler T cell ligand α-galactosylceramide inhibited lymph node metastasis of highly metastatic melanoma cells
27. + T cells in the pathogenesis of organ-specific autoimmune diseases
28. T helper phenotype and genetic susceptibility in experimental Lyme disease
29. T cell genetic background determines maintenance of IL-12 signaling: Effects on BALB/c and B10.D2 T helper cell type 1 phenotype development
30. + T lymphocytes
31. + T cells in major histocompatibility complex class II-deficient mice
32. A novel monoclonal antibody permitting recognition of NKT cells in various mouse strains
33. Functional and pheno-typical characteristics of hepatic NK-like T cells in NK1.1-positive and -negative mouse strains
34. + NK T lymphocytes
35. CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides
36. Mouse CD1-specific NK1 T cells: Development, specificity, and function
37. Germ-line transmission of a disrupted β2-microglobulin gene produced by homologous recombination in embryonic stem cells
38. Immunoglobulin E production in the absence of interleukin-4-secreting CD1d- dependent cells
39. Induction of interleukin 2 receptor β chain expression by self-recognition in the thymus
40. + T cells that promptly produce interleukin 4
41. Infectious Th1 and Th2 autoimmunity in diabetes-prone mice
42. Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
43. Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice
44. Characterization of the adjuvant effect of IL-12 and efficacy of IL-12 inhibitiors in type II collagen-induced arthritis
45. IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function
46. Prevention of experimental autoimmune uveoretinitis by monoclonal antibody to interleukin-12
47. - (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10
48. + T cells prevent sponteneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice
49. Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes
50. +-like thymocytes in the NOD mouse