Nitric oxide is a regulator of bone remodelling

Journal of Pharmacy and Pharmacology

Volumn 49, Issue 9, 1997, Pages 897-902

  Chae, Han Jung ^a   Park, Rae Kil ^b   Chung, Hun Taeg ^b   Kang, Jang Sook ^a   Kim, Myung Sun ^b   Choi, Du Young ^b   Bang, Byung Gwan ^a   Kim, Hyung Ryong ^a,b  

^a Institute Wonkwang Biomaterial Implant   (South Korea)

^b Wonkwang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CALCITRIOL; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1BETA; NITRIC OXIDE; NITROPRUSSIDE SODIUM; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BONE ATROPHY; BONE METABOLISM; BONE REMODELING; CALCIFICATION; CELL DIFFERENTIATION; CELL LINE; CELL SECRETION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; FETUS; MOUSE; NEWBORN; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OSTEOSARCOMA; PATHOGENESIS; PERIODONTAL DISEASE; RHEUMATOID ARTHRITIS;

EID: 0030800914     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1997.tb06132.x     Document Type: Article

References (34)

1. Bertolini, D. R., Nedwin, G. E., Bringman, D., Smith, D., Mundy, G. R. (1986) Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors. Nature 319: 516-519
2. Bredt, D. S., Hwang, P. M., Glatt, C. E., Lowenstein, C., Reed, R. R., Snyder, S. H. (1991) Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature 351: 714-718
3. Damoulis, P. D., Hauschka, P. V. (1994) Cytokines induce nitric oxide production in mouse osteoblasts. Biochem. Biophys. Res. Commun. 201: 924-931
4. Damoulis, P. D., Hauschka, P. V. (1997) Nitric oxide acts in conjunction with proinflammatory cytokine to promote cell death in osteoblasts. J. Bone. Miner. Res. 12: 412-422
5. Fox, S. W., Chambers, T. J., Chow, J. W. M. (1995) Nitric oxide is an early mediator of the induction of bone formation by mechanical stimulation. J. Bone Miner. Res. 10 (Suppl. 1): S204 (abstract)
6. Gowen, M., Wood, D. D., Ihrie, E. J., McGuire, M. K. B., Russell, R. G. G. (1983) An interleukin-1 like factor stimulates bone resorption in vitro. Nature 306: 378-380
7. Gowen, M., Nedwin, G. E., Mundy, G. R. (1986) Preferential inhibition of cytokine stimulated bone resorption by recombinant interferon gamma. J. Bone Miner. Res. 1: 469-473
8. 15N] nitrate in biological fluids. Anal. Biochem. 128: 131-138
9. Hibbs, J. B., Traintor, R. R., Vavrin, Z., Rachlin, E. M. (1988) Nitric oxide: a cytotoxic activated macrophage effector molecule. Biochem. Biophys. Res. Commun. 157: 87-95
10. Hukkanen, M., Hughes, F. J., Buttery, L. D., Gross, S. S., Evans, T.J., Seddon, S., Riveros-Moreno, V., MacIntyre, I., Polak, J. M. (1995) Cytokine-stimulated expression of inducible nitric oxide synthase by mouse, rat, and human osteoblast-like cells and its functional role in osteoblast metabolic activity. Endocrinology 136: 5445-5453
11. Kasten, T. P., Collin-Osdoby, P., Patel, N., Osdoby, P., Krunowski, M., Misko, T. P., Settle, S. L., Currie, M. G., Nickols, G. A. (1994) Potentiation of osteoclast bone-resorption activity by inhibition of nitric oxide synthase. Proc. Natl Acad. Sci. USA 91: 3569-3573
12. Lamas, S., Marsden, P. A., Li, G. K., Tempst, P., Michel., T. (1992) Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. Proc. Natl Acad. Sci. USA 89: 6348-6352
13. Lowenstein, C. J., Snyder., S. H. (1992) Nitric oxide, a novel biological messenger. Cell 70: 705-707
14. Löwik, C. W. G. M., Nibbering, P. H., Van der Ruit, M., Papapoulos, S. E. (1994) Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclast bone resorption. J. Clin. Invest. 93: 1465-1472
15. MacIntyre , I., Zaidi, M., Towhidul Alam, A. S. T., Datta, H. K., Moonga, B. S., Lidbury, P. S., Hecker, M., Vane, J. R. (1991) Osteoclast inhibition : an action of nitric oxide not mediated by cyclic GMP. Proc. Natl Acad. Sci. USA 88: 2936-2940
16. McCall, T. B., Boughton-Smith, N. K., Palmer, R. M. J., Whittle, B. J. R., Moncata, S. (1989) Synthesis of nitric oxide from L-arginine by neurophils. Biochem. J. 261: 293-296
17. Moncada, S., Higgs, A. (1993) The L-arginine nitric oxide pathway. N. Engl. J. Med. 329: 2002-2012
18. Moncada, S., Palmer, R. M. J., Higgs, E. A. (1991) Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43: 109-142
19. Nathan, C. (1992) Nitric oxide as a secretory product of mammalian cells. Fed. Am. Soc. Exp. Biol. J. 6. 3051-3064
20. Nathan, C., Hibbs Jr., J. B. (1991) Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opin. Immunol. 3: 65-70
21. Nussler, A. K., DiSilvio, M., Billiar, T. R., Hoffman, R. A., Geller, D. A., Selby, R., Madrigas, J., Simmons, R. L. (1992) Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin. J. Exp. Med. 176: 261-264
22. Palmer, R. M. J., Andrews, T., Foxwell, N. A., Moncada, S. (1992) Glucocortocoids do not affects the induction of a novel calcium dependent nitric oxide synthase in rabbit chondrocytes. Biochem. Biophys. Res. Commun. 188: 209-215
23. Parfitt, A. M. (1987) Bone remodelling and bone loss: understanding the physiology of osteoporosis. Clin. Obstet. Gynecol. 30: 789-811
24. Pitsillides, A. A., Rawlinson, S. C. F., Suswillo, R. F. S., Zaman, G., Nijweide, P. J., Lanyon, L. E. (1995) Mechanical strain-induced nitric oxide production by oseoblasts and osteocytes. J. Bone Miner. Res. 10 (Suppl. 1). S217
25. Ralston, S. H., Grabowski, P. S. (1996) Mechanisms of cytokine induced bone resorption: role of nitric oxide, cyclic guanosine monophosphate, and prostaglandins. Bone 19: 29-33
26. Ralston, S. H., Helfrich, M., Grabowski, P. S., Benjamin, N. (1993) A role for nitric oxide in the regulation of cytokine-induced resorption. J. Bone Miner. Res. 8 (Suppl. 1): 383
27. Ralston, S. H., Todd, D., Helfrich, M. H., Benjamin, N., Grabowski, P. S. (1994) Human osteoblast-like cells produce nitric oxide and express inducible nitric oxide synthase. Endocrinology 135: 330-336
28. Riancho, J. A., Zarrabeitia, M. T., Fernandez-Luna, J. I., Gonzalez-Macias, J. (1995) Mechanisms controlling nitric oxide synthesis in osteoblasts. Mol. Cell. Endocrinol. 107: 87-93
29. Roodman, G. D. (1993) Role of cytokines in the regulation of bone resorption. Calcif. Tissue Int. 53: S94-S98
30. Shultz, P. J. M., Tayeh, M. A., Marletta, M. A., Raij, L. (1991) Synthesis and action of nitric oxide in rat glomerular mesangial cells. Am. J. Physiol. 261: F600-F609
31. Silve, C. M., Hradek, G. T., Jones, A. L., Arnaud, C. D. (1982) Parathyroid hormone receptor in intact embryonic chicken bone: characterization and cellular localization. J. Cell Biol. 94: 379-386
32. Stuehr, D. J., Nathan, C. (1989) Nitric oxide: a macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J. Exp. Med. 169: 1543-1545
33. Wong, G. L., Cohn, D. V. (1974) Separation of parathyroid hormone and calcitonin sensitive cells from non-responsive bone cells. Nature 252: 713-715
34. Xie, Q. W., Cho, H. J., Calaycay, J., Mumford, R. A., Swiderek, K. M., Lee, T. D., Ding, A., Troso, T., Nathan, C. (1992) Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 256: 225-228