Human ornithine transcarbamylase: Crystallographic insights into substrate recognition and conformational changes

Biochemical Journal

Volumn 354, Issue 3, 2001, Pages 501-509

  Shi, D ^a   Morizono, H ^a   Yu, X ^a   Tong, L ^a   Allewell, N M ^a   Tuchman, M ^a  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

Carbamoyltransferase; Crystal structure; Domain movement; Substrate recognition

Indexed keywords

CONFORMATIONS; CRYSTALLIZATION; CRYSTALS; ENZYMES; SUBSTRATES;

HUMAN ORNITHINE TRANSCARBAMYLASE;

CRYSTALLOGRAPHY;

ORNITHINE CARBAMOYLTRANSFERASE;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BINDING SITES; CARBAMYL PHOSPHATE; CRYSTALLOGRAPHY, X-RAY; HUMANS; KINETICS; MACROMOLECULAR SUBSTANCES; METALLOPROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; ORNITHINE CARBAMOYLTRANSFERASE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SOLVENTS; SUBSTRATE SPECIFICITY;

EID: 0035868405     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3540501     Document Type: Article

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