Characterization of a Novel Isoform of Caspase-9 That Inhibits Apoptosis

Journal of Biological Chemistry

Volumn 276, Issue 15, 2001, Pages 12190-12200

  Angelastro, James M ^a   Moon, Nah Yong ^a   Liu, David X ^a   Yang, An Suei ^a   Greene, Lloyd A ^a   Franke, Thomas F ^a  

^a Columbia Univ Coll of Phys/Surgs ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; ENZYMES; TISSUE;

APOPTOSIS; CELL DEATH;

BIOCHEMISTRY;

CASPASE 9; CASPASE 9 CARBOXYL TERMINAL DIVERGENT; ISOENZYME; UNCLASSIFIED DRUG; CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, RAT; CASP9 PROTEIN, HUMAN; CASP9 PROTEIN, RAT; CASPASE; CASPASE 3; DNA; PRIMER DNA; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; ENZYME INDUCTION; ENZYME MECHANISM; ENZYME STRUCTURE; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; RAT; ANIMAL; CELL LINE; CELL STRAIN; CHEMISTRY; ENZYME ACTIVATION; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; PHYSIOLOGY;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; CASPASE 3; CASPASE 9; CASPASES; CELL LINE; CLONING, MOLECULAR; DNA; DNA PRIMERS; ENZYME ACTIVATION; HUMANS; MOLECULAR SEQUENCE DATA; PC12 CELLS; RATS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 0035853709     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009523200     Document Type: Article

References (34)

1. Green, D. R., and Reed, J. C. (1998) Science 281, 1309-1312
2. Thornberry, N. A., and Lazebnik, Y. (1998) Science 281, 1312-1316
3. Salvesen, G. S., and Dixit, V. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 10964-10967
4. Stennicke, H. R., Deveraux, Q. L., Humke, E. W., Reed, J. C., Dixit, V. M., and Salvesen, G. S. (1999) J. Biol. Chem. 274, 8359-8362
5. Zheng, T. S., Hunot, S., Kuida, K., and Flavell, R. A. (1999) Cell Death Differ, 6, 1043-1053
6. Slee, E. A., Harte, M. T., Kluck, R. M., Wolf, B. B., Casiano, C. A., Newmeyer, D. D., Wang, H. G., Reed, J. C., Nicholson, D. W., Alnemri, E. S., Green, D. R., and Martin, S. J. (1999) J. Cell Biol. 144, 281-292
7. Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T., and Alnemri, E. S. (1998) Mol. Cell 1, 949-957
8. Stennicke, H. R., and Salvesen, G. S. (1997) J. Biol. Chem. 272, 25719-25723
9. Rodriguez, J., and Lazebnik, Y. (1999) Genes Dev. 13, 3179-3184
10. Wang, L., Miura, M., Bergeron, L., Zhu, H., and Yuan, J. (1994) Cell 78, 739-750
11. Fujita, E., Jinbo, A., Matuzaki, H., Konishi, H., Kikkawa, U., and Momoi, T. (1999) Biochem. Biophys. Res. Commun. 264, 550-555
12. Seol, D. W., and Billiar, T. R. (1999) J. Biol. Chem. 274, 2072-2076
13. Srinivasula, S. M., Ahmad, M., Guo, Y., Zhan, Y., Lazebnik, Y., Fernandes-Alnemri, T., and Alnemri, E. S. (1999) Cancer Res. 59, 999-1002
14. Hu, S., Vincenz, C., Ni, J., Gentz, R., and Dixit, V. M. (1997) J. Biol. Chem. 272, 17255-17257
15. Greene, L. A., and Tischler, A. S. (1976) Proc. Natl. Acad. Sci. U. S. A. 73, 2424-2428
16. Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G. G., Salvesen, G. S., and Dixit, V. M. (1995) Cell 81, 801-809
17. Stennicke, H. R., and Salvesen, G. S. (1999) Methods 17, 313-319
18. Stennicke, H. R., Jurgensmeier, J. M., Shin, H., Deveraux, Q., Wolf, B. B., Yang, X., Zhou, Q., Ellerby, H. M., Ellerby, L. M., Bredesen, D., Green, D. R., Reed, J. C., Froelich, C. J., and Salvesen, G. S. (1998) J. Biol. Chem. 273, 27084-27090
19. Angelastro, J. M., Ho, C. L., Frappier, T., Liem, R. K., and Greene, L. A. (1998) J. Neurochem. 70, 540-549
20. Greene, L. A., Farinelli, S. E., Cunningham, M. E., and Park, D. S. (1998) in Culturing Nerve Cells (Banker, G. G. K., ed) pp. 161-187, MIT Press, Cambridge, MA
21. Troy, C. M., Stefanis, L., Greene, L. A., and Shelanski, M. L. (1997) J. Neurosci. 17, 1911-1918
22. Smith, T. F., and Waterman, M. S. (1981) J. Mol. Biol. 147, 195-197
23. Yang, A.-S., and Honig, B. (1999) Proteins Suppl. 3, 66-72
24. Rotonda, J., Nicholson, D. W., Fazil, K. M., Gallant, M., Gareau, Y., Labelle, M., Peterson, E. P., Rasper, D. M., Ruel, R., Vaillancourt, J. P., Thornberry, N. A., and Becker, J. W. (1996) Nat. Struct. Biol. 3, 619-625
25. Mittl, P. R., Di Marco, S., Krebs, J. F., Bai, X., Karanewsky, D. S., Priestle, J. P., Tomaselli, K. J., and Grutter, M. G. (1997) J. Biol. Chem. 272, 6539-6547
26. Wilkins, M. R., Lindskog, I., Gasteiger, E., Bairoch, A., Sanchez, J. C., Hochstrasser, D. F., and Appel, R. D. (1997) Electrophoresis 18, 403-408
27. Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P., Chapman, K. T., and Nicholson, D. W. (1997) J. Biol. Chem. 272, 17907-17911
28. Stefanis, L., Park, D. S., Friedman, W. J., and Greene, L. A. (1999) J. Neurosci. 19, 6235-6247
29. Juin, P., Hueber, A. O., Littlewood, T., and Evan, G. (1999) Genes Dev. 13, 1367-1381
30. Janicke, R. U., Sprengart, M. L., Wati, M. R., and Porter, A. G. (1998) J. Biol. Chem. 273, 9357-9360
31. Ritter, P. M., Marti, A., Blanc, C., Baltzer, A., Krajewski, S., Reed, J. C., and Jaggi, R. (2000) Eur. J. Cell Biol. 79, 358-364
32. Faleiro, L., and Lazebnik, Y. (2000) J. Cell Biol. 151, 951-960
33. Alnemri, E. S., Fernandes-Alnemri, T., and Litwack, G. (1995) J. Biol. Chem. 270, 4312-4317
34. Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., Bodmer, J. L., Schroter, M., Burns, K., Mattmann, C., Rimoldi, D., French, L. E., and Tschopp, J. (1997) Nature 388, 190-195