Solution structure of Co(III)-bleomycin-OOH bound to a phosphoglycolate lesion containing oligonucleotide: Implications for bleomycin-induced double-strand DNA cleavage

Biochemistry

Volumn 40, Issue 20, 2001, Pages 5894-5905

  Hoehn, Silvia T ^a   Junker, Hans Dieter ^a   Bunt, Richard C ^a   Turner, Christopher J ^b   Stubbe, JoAnne ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; COMPLEXATION; CYTOLOGY; DNA; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SOLUTIONS; TOXICITY;

SOLUTION STRUCTURE;

BIOCHEMISTRY;

BLEOMYCIN DERIVATIVE; COPPER DERIVATIVE; DOUBLE STRANDED DNA; GLYCOLIC ACID DERIVATIVE; HYDROPEROXIDE; IRON; OLIGONUCLEOTIDE; OXYGEN;

ARTICLE; CONFORMATION; CYTOTOXICITY; DISSOCIATION; DRUG STRUCTURE; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANTIBIOTICS, ANTINEOPLASTIC; BASE SEQUENCE; BINDING SITES; BLEOMYCIN; DNA; DNA DAMAGE; GLYCOLATES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDES; PROTONS; SOLUTIONS; THIAZOLES; TITRIMETRY;

EID: 0035918531     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi002635g     Document Type: Article

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