Agonist efficacy and allosteric models of receptor action

Annals of the New York Academy of Sciences

Volumn 812, Issue , 1997, Pages 98-115

  Onaran, H Ongun ^a   Costa, Tommaso ^b  

^a ANKARA UNIVERSITY   (Turkey)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

RECEPTOR;

AGONIST; ALLOSTERISM; GENETIC ENGINEERING; MATHEMATICAL MODEL; MOLECULAR CLONING; MUTAGENESIS; PROBABILITY; REVIEW; SIGNAL TRANSDUCTION;

EID: 0001870572     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb48150.x     Document Type: Review

References (24)

1. KENAKIN, T. P. 1992. Pharmacological analysis of drug-receptor interaction. Raven Press. New York.
2. BLACK, J. W. & P. LEFF. 1983. Proc. R. Soc. London Ser. B 220: 141-162.
3. STEPHENSON, R. P. 1956. Arch. Int. Pharmacodyn. Ther. 99: 32-49.
4. FURCHGOTT, R. F. 1966. In Advances in Drug Research, Vol. 3. N. J. Harper & A. B. Simmonds, Eds.: 21-55. Academic Press.
5. MONOD, J., J. P. CHANGEUX & F. JACOB. 1963. J. Mol. Biol. 6: 306-329.
6. MONOD, J., J. WYMAN & J. P. CHANGEUX. 1965. J. Mol. Biol. 12: 88-118.
7. WYMAN, J. 1987. J. Am. Chem. Soc. 89: 2202-2218.
8. WEBER, G. 1972. Biochemistry 11: 864-878.
9. DEL CASTILLO, J. & B. KATZ. 1957. Proc. R. Soc. London Biol. Sci. 146: 369-381.
10. KARLIN, A. 1967. J. Theor. Biol. 16: 306-320.
11. THRON, C. D. 1973. Mol. Pharmacol. 9: 1-9.
12. COLQUHOUN, D. 1973. In Drug Receptors. H. P. Rang, Ed.: 149-182. MacMillan.
13. LEFF, P. 1995. TIPS 16: 89-97.
14. DE LEAN, A., J. M. STADEL & R. J. LEFKOWITZ. 1980. J. Biol. Chem. 255: 7108-7117.
15. WREGGET, K. A. & A. DE LEAN. 1984. Mol. Pharmacol. 26: 214-227.
16. EHLERT, F. J. 1985. Mol. Pharmacol. 28: 410-421.
17. MACKAY, D. 1990. J. Theor. Biol. 142: 415-427.
18. KENAKIN, T. P. & P. H. MORGAN. 1989. Mol. Pharmacol. 35: 214-222.
19. COSTA, T., Y. OGINO, P. MUNSON, H. O. ONARAN & D. RODBARD. 1992. Mol. Pharmacol. 41: 549-560.
20. WEBER, G. 1973. Adv. Protein Chemistry 29: 1-83.
21. WYMAN, J. & D. W. ALLEN. 1951. J. Polymer Sci. 7: 499-518.
22. KJELSBERG, M. A., S. COTECCHIA, J. OSTROWSKI, M. CARON & R. J. LEFKOWITZ. 1992. J. Biol. Chem. 267: 1430-1433.
23. SAMAMA, P., S. COTECCHIA, T. COSTA & R. J. LEFKOWITZ. 1993. J. Biol. Chem. 268:4625-4636.
24. HILL, T. I. 1956. Statistical Mechanics. McGraw-Hill. New York.