Loss of activation of G(s) but not G(i) following expression of an α(2A)-adrenoceptor-G(i1)α fusion protein

FEBS Letters

Volumn 436, Issue 1, 1998, Pages 46-50

  Sautel, Martine ^a   Milligan, Graeme ^a  

^a Molecular Pharmacology Group   (United Kingdom)

Author keywords

AC, adenylyl cyclase; Adenylyl cyclase; Adrenaline; G protein; G protein, guanine nucleotide binding protein; GPCR, G protein coupled receptor; Receptor

Indexed keywords

ADENYLATE CYCLASE; ALPHA 2 ADRENERGIC RECEPTOR; BRIMONIDINE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; IDAZOXAN; OXYMETAZOLINE; PERTUSSIS TOXIN; RECEPTOR PROTEIN; ADENYLATE CYCLASE TOXIN; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; BORDETELLA VIRULENCE FACTOR; CHOLERA TOXIN; FORSKOLIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; QUINOXALINE DERIVATIVE; RECEPTOR, ADRENERGIC, ALPHA 2A; RECEPTOR, ADRENERGIC, ALPHA-2A; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; BINDING SITE; DOSE RESPONSE; DRUG EFFECT; GENETICS; METABOLISM;

ADENYLATE CYCLASE; ADENYLATE CYCLASE TOXIN; ADRENERGIC ALPHA-AGONISTS; ANIMALS; BINDING SITES; CHOLERA TOXIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; OXYMETAZOLINE; PERTUSSIS TOXIN; QUINOXALINES; RATS; RECEPTORS, ADRENERGIC, ALPHA-2; RECOMBINANT FUSION PROTEINS; VIRULENCE FACTORS, BORDETELLA;

EID: 0032566432     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01094-1     Document Type: Article

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