Use of the Tetracycline-controlled Transcriptional Silencer (tTS) to Eliminate Transgene Leak in Inducible Overexpression Transgenic Mice

Journal of Biological Chemistry

Volumn 276, Issue 27, 2001, Pages 25222-25229

  Zhu, Zhou ^b   Ma, Bing ^b   Homer, Robert J ^a   Zheng, Tao ^b   Elias, Jack A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Dept of Internal Medicine ^*

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL ACTIVATION; GENES; PROTEINS;

ALVEOLAR ENLARGEMENT; TRANSCRIPTIONAL REPRESSORS;

GENETIC ENGINEERING;

CLARA CELL 10 PROTEIN; CLARA CELL PROTEIN; DOXYCYCLINE; DOXYCYCLINE INDUCIBLE REVERSE TETRACYCLINE TRANSACTIVATOR; HYBRID PROTEIN; INTERLEUKIN 13; REPRESSOR PROTEIN; REVERSE TETRACYCLINE TRANSACTIVATOR PROTEIN; TETRACYCLINE CONTROLLED TRANSCRIPTIONAL SILENCER PROTEIN; TETRACYCLINE DERIVATIVE; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; RECOMBINANT PROTEIN; TETRACYCLINE; TETRACYCLINE RESISTANCE ENCODING TRANSPOSON REPRESSOR PROTEIN; TETRACYCLINE RESISTANCE-ENCODING TRANSPOSON REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; ZFP354A PROTEIN, MOUSE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; LUNG VOLUME; METAPLASIA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; TRANSGENE; ANIMAL; BIOSYNTHESIS; DRUG EFFECT; GENETICS; LUNG; TRANSACTIVATION; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

ANIMALS; DNA-BINDING PROTEINS; DOXYCYCLINE; GENE EXPRESSION REGULATION; INTERLEUKIN-13; LUNG; MICE; MICE, TRANSGENIC; PHENOTYPE; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; TETRACYCLINE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSGENES;

EID: 0035816681     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101512200     Document Type: Article

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