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Volumn 276, Issue 27, 2001, Pages 25366-25371
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Phe-308 and Phe-312 in transmembrane domain 7 are major sites of α1-adrenergic receptor antagonist binding: Imidazoline agonists bind like antagonists
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NONE
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Author keywords
[No Author keywords available]
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Indexed keywords
BIOCHEMISTRY;
CELL MEMBRANES;
GENETIC ENGINEERING;
MUTAGENESIS;
ADRENERGIC RECEPTORS;
ANTAGONIST BINDING;
PROTEINS;
2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN;
5 METHYLURAPIDIL;
8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE;
ADRENALIN;
ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT;
ALPHA 1A ADRENERGIC RECEPTOR;
CIRAZOLINE;
CLONIDINE;
GUANINE NUCLEOTIDE BINDING PROTEIN;
IMIDAZOLINE;
METHOXAMINE;
NIGULDIPINE;
OXYMETAZOLINE;
PHENYLALANINE;
PHENYLEPHRINE;
PRAZOSIN;
RHODOPSIN;
5-METHYLURAPIDIL;
ALPHA 1 ADRENERGIC RECEPTOR;
ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT;
DIHYDROPYRIDINE DERIVATIVE;
DIOXANE DERIVATIVE;
IMIDAZOLE DERIVATIVE;
PIPERAZINE DERIVATIVE;
ANIMAL CELL;
ARTICLE;
BINDING AFFINITY;
CONTROLLED STUDY;
DRUG MECHANISM;
DRUG PROTEIN BINDING;
HUMAN;
HUMAN CELL;
LIGAND BINDING;
MUTAGENESIS;
NONHUMAN;
PRIORITY JOURNAL;
PROTEIN ANALYSIS;
PROTEIN BINDING;
PROTEIN DOMAIN;
RAT;
STRUCTURE ANALYSIS;
TRANSMEMBRANE DOMAIN 7;
AMINO ACID SEQUENCE;
ANIMAL;
CELL MEMBRANE;
CHEMICAL STRUCTURE;
DRUG ANTAGONISM;
HAMSTER;
METABOLISM;
MOLECULAR GENETICS;
NUCLEOTIDE SEQUENCE;
PROTEIN SECONDARY STRUCTURE;
STRUCTURE ACTIVITY RELATION;
ANIMALIA;
ADRENERGIC ALPHA-ANTAGONISTS;
AMINO ACID SEQUENCE;
ANIMALS;
CELL MEMBRANE;
CLONIDINE;
CONSERVED SEQUENCE;
CRICETINAE;
DIHYDROPYRIDINES;
DIOXANES;
HUMANS;
IMIDAZOLES;
MODELS, MOLECULAR;
MOLECULAR SEQUENCE DATA;
OXYMETAZOLINE;
PHENYLALANINE;
PIPERAZINES;
PRAZOSIN;
PROTEIN STRUCTURE, SECONDARY;
RATS;
RECEPTORS, ADRENERGIC, ALPHA-1;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 0035816665
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M103152200 Document Type: Article |
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Times cited : (61)
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References (25)
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