Cytotoxic targeting of isolectin IB4-binding sensory neurons

Neuroscience

Volumn 108, Issue 1, 2001, Pages 143-155

  Vulchanova, L ^a   Olson, T H ^a   Stone, L S ^a   Riedl, M S ^a   Elde, R ^a   Honda, C N ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

BSI; Hypoalgesia; Lectin; Nociception; Rat; Saporin

Indexed keywords

ISOLECTIN IB4; LECTIN; SAPORIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY; HISTOLOGY; IN VIVO STUDY; MALE; NOCICEPTION; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TARGETING; RAT; SCIATIC NERVE; SENSORY NERVE; SKIN NERVE; SPINAL CORD; SPINAL GANGLION;

ANIMALS; CELL COUNT; IMMUNOTOXINS; LECTINS; MALE; MYELIN SHEATH; N-GLYCOSYL HYDROLASES; NEURONS, AFFERENT; NOCICEPTORS; PAIN THRESHOLD; PLANT PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SCHWANN CELLS; SCIATIC NERVE;

EID: 0035814454     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00377-3     Document Type: Article

References (46)

1. Distribution and targeting of a mu-opioid receptor (MOR1) in brain and spinal cord
2. Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons
3. Stability and plasticity of primary afferent projections following nerve regeneration and central degeneration
4. Endogenous nerve growth factor regulates the sensitivity of nociceptors in the adult rat
5. A distinct subgroup of small DRG cells express GDNF receptor components and GDNF is protective for these neurons after nerve injury
6. The expression of P2X3 purinoreceptors in sensory neurons: Effects of axotomy and glial-derived neurotrophic factor
7. Cutaneous nociceptors
8. Impaired nociception and pain sensation in mice lacking the capsaicin receptor
9. The capsaicin receptor: A heat-activated ion channel in the pain pathway
10. Quantitative assessment of tactile allodynia in the rat paw
11. Distinct ATP receptors on pain-sensing and stretch-sensing neurons
12. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
13. Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat
14. Schwann cell degeneration induced by doxorubicin (adriamycin)
15. Immunocytochemical localization of the vanilloid receptor 1 (VR1): Relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites
16. The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat
17. Developmental alterations in nociceptive threshold, immunoreactive calcitonin gene-related peptide and substance P, and fluoride-resistant acid phosphatase in neonatally capsaicin-treated rats
18. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
19. Epidermal denervation and its effects on keratinocytes and Langerhans cells
20. Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro
21. Central projections of the sciatic, saphenous, median, and ulnar nerves of the rat demonstrated by transganglionic transport of choleragenoid-HRP (B-HRP) and wheat germ agglutinin-HRP (WGA-HRP)
22. Cutaneous sensory receptors in the rat foot
23. Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor
24. The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule
25. The induction of pain: An integrative review
26. Presence or absence of TrkA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections
27. IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life
28. Fluoride-resistant acid phosphatase-containing neurones in dorsal root ganglia are separate from those containing substance P or somatostatin
29. Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves
30. Regulation of myelinated nociceptor function by nerve growth factor in neonatal and adult rats
31. Effects of trkB and trkC neurotrophin receptor agonists on thermal nociception: A behavioral and electrophysiological study
32. Lectin and neuropeptide labeling of separate populations of dorsal root ganglion neurons and associated 'nociceptor' thin axons in rat testis and cornea whole-mount preparations
33. Selective neuronal glycoconjugate expression in sensory and autonomic ganglia: Relation of lectin reactivity to peptide and enzyme markers
34. Tackling pain at the source: New ideas about nociceptors
35. Ribosome-inactivating proteins from plants: Present status and future prospects
36. Evidence for glycoconjugate in nociceptive primary sensory neurons and its origin from the Golgi complex
37. Histochemical localization of galactose-containing glycoconjugate at peripheral nodes of Ranvier in the rat
38. Overexpression of nerve growth factor in skin selectively affects the survival and functional properties of nociceptors
39. Isolectin B4-positive and -negative nociceptors are functionally distinct
40. The cloned capsaicin receptor integrates multiple pain-producing stimuli
41. Increased uptake and transport of cholera toxin B-subunit in dorsal root ganglion neurons after peripheral axotomy: Possible implications for sensory sprouting
42. P2X3 is expressed by DRG neurons that terminate in inner lamina II
43. Depletion of IB4-binding sensory neurons results in elevated nociceptive thresholds
44. Transganglionic transport and binding of the isolectin B4 from Griffonia simplicifolia I in rat primary sensory neurons
45. Neuronal lesioning with axonally transported toxins
46. Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: Electrophysiological evidence