Characterization of RAD52 homologs in the fission yeast Schizosaccharomyces pombe

Mutation Research - DNA Repair

Volumn 461, Issue 4, 2001, Pages 311-323

  Van Den Bosch, Michael ^a   Vreeken, Kees ^a   Zonneveld, José B M ^a   Brandsma, Jourica A ^b   Lombaerts, Marcel ^b   Murray, Johanne M ^c   Lohman, Paul H M ^a   Pastink, Albert ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

Double strand breaks; Homologous recombination; Rad52 homologs; S. pombe; X ray sensitivity

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DELETION MUTANT; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; FUNGUS MUTANT; GENE CONVERSION; GENE MUTATION; NONHUMAN; PHENOTYPE; PLASMID; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE; X RAY; YEAST;

AMINO ACID SEQUENCE; CELL SURVIVAL; CLONING, MOLECULAR; DNA-BINDING PROTEINS; FUNGAL PROTEINS; MEIOSIS; MOLECULAR SEQUENCE DATA; RAD52 DNA REPAIR AND RECOMBINATION PROTEIN; RECOMBINATION, GENETIC; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPORES, FUNGAL; ULTRAVIOLET RAYS;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCES POMBE; SCHIZOSACCHAROMYCES POMBE;

EID: 0035808728     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(00)00060-4     Document Type: Article

References (49)

1. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
2. Repair and consequences of double-strand breaks in DNA
3. Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein
4. Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins
5. Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51
6. DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA
7. Function of yeast Rad52 protein as a mediator between replication protein A the Rad51 recombinase
8. Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase
9. Stimulation by Rad52 of yeast Rad51-mediated recombination
10. Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A
11. Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins
12. The RAD52 epistasis group in mammalian double strand break repair
13. Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro
14. Synergistic actions of Rad51 and Rad52 in recombination and DNA repair
15. Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing
16. Visualisation of human rad52 protein and its complexes with hRad51 and DNA
17. Binding of double-strand breaks in DNA by human Rad52 protein
18. Analysis of DNA double strand breakage and repair using orthogonal field alternation gel electrophoresis
19. Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells
20. Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation
21. Targeted disruption of the Rad51 gene leads to lethality in embryonic mice
22. A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53
23. Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death
24. Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination
25. Reduced X-ray resistance and homologous recombination frequencies in a RAD54(-/-) mutant of the chicken DT40 cell line
26. The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination
27. Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52
28. Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation
29. A Rad52 homolog is required for RAD51-independent mitotic recombination in Saccharomyces cerevisiae
30. The fission yeast rad22 gene, having a function in mating-type switching and repair of DNA damages, encodes a protein homolog to Rad52 of Saccharomyces cerevisiae
31. Cloning and characterisation of the Schizosaccharomyces pombe rad32 gene: a gene required for repair of double strand breaks and recombination
32. Cloning the RAD51 homologue of Schizosaccharomyces pombe
33. +, a gene involved in the repair of radiation damage and replication fidelity
34. +, a Schizosaccharomyces pombe homolog of the Saccharomyces cerevisiae RAD51 gene
35. A new recombinational DNA repair gene from Schizosaccharomyces pombe with homology to Escherichia coli RecA
36. A recombination repair gene of Schizosaccharomyces pombe, rhp57, is a functional homolog of the Saccharomyces cerevisiae RAD57 gene and is phylogenetically related to the human XRCC3 gene
37. Two related families of retrotransposons from Schizosaccharomyces pombe
38. Fission yeast Schizosaccharomyces pombe correctly excises a mammalian RNA transcript intervening sequence
39. Thiamine-repressible expression vectors pREP and pRIP for fission yeast
40. Cassette for the generation of sequential gene disruptions in the yeast Schizosaccharomyces pombe
41. + genes
42. Efficient targeted integration at leu1-32 and ura4-294 in Schizosaccharomyces pombe
43. Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52
44. Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis
45. RDH54, a RAD54 homologue in Saccharomyces cerevisiae, is required for mitotic diploid-specific recombination and repair and for meiosis
46. A double-strand break repair component is essential for S phase completion in fission yeast cell cycling