The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination

Molecular and Cellular Biology

Volumn 17, Issue 10, 1997, Pages 6097-6104

  Kooistra, Rolf ^a   Vreeken, Kees ^a   Zonneveld, José B M ^a   De Jong, Anja ^a   Eeken, Jan C J ^a   Osgood, Chris J ^a,c   Buerstedde, Jean Marie ^b   Lohman, Paul H M ^a   Pastink, Albert ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

^c OLD DOMINION UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DOUBLE STRANDED DNA; MESYLIC ACID METHYL ESTER; RECA PROTEIN; RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENT; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; DROSOPHILA MELANOGASTER; EMBRYO; EVOLUTION; FEMALE; IN SITU HYBRIDIZATION; IONIZING RADIATION; MALE; MITOSIS; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ISOLATION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; X RAY;

ANIMALIA; DROSOPHILA MELANOGASTER; MAMMALIA; MELANOGASTER; SACCHAROMYCES CEREVISIAE;

EID: 0030864010     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.10.6097     Document Type: Article

References (65)

1. Aboussekhra, A., R. Chanet, A. Adjiri, and F. Fabre. 1992. Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins. Mol. Cell. Biol. 12:3224-3234.
2. Akaboshi, E., Y. Inoue, and H. Ryo. 1994. Cloning of the cDNA and genomic DNA that correspond to the recA-like gene of Drosophila melanogaster. Jpn. J. Genet. 69:663-670.
3. Bai, Y., and L. S. Symington. 1996. A Rad52 homolog is required for RAD51-independent mitotic recombination in Saccharomyces cerevisiae. Genes Dev. 10:2025-2037.
4. Basile, G., M. Aker, and R. K. Mortimer. 1992. Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51. Mol. Cell. Biol. 12:3235-3246.
5. Beall, E. L., and D. C. Rio. 1996. Drosophila IRBP/Ku p70 corresponds to the mutagen-sensitive mus309 gene and is involved in P-element excision in vivo. Genes Dev. 10:921-933.
6. Becker, H. J. 1976. Mitotic recombination, p. 1019-1087. In M. Ashburner and E. Novitski (ed.), The genetics and biology of Drosophila, vol. 1c. Academic Press, Ltd., London, United Kingdom.
7. Bendixen, C., I. Sunjevaric, R. Bauchwitz, and R. Rothstein. 1994. Identification of a mouse homologue of the Saccharomyces cerevisiae recombination and repair gene, RAD52. Genomics 23:300-303.
8. Bezzubova, O., H. Schmidt, K. Ostermann, W.-D. Heyer, and J.-M. Buerstedde. 1993. Identification of a chicken RAD52 homologue suggests conservation of the RAD52 recombination pathway throughout the evolution of higher eukaryotes. Nucleic Acids Res. 21:5945-5949.
9. Bezzubova, O., A. Shinohara, R. G. Mueller, H. Ogawa, and J.-M. Buerstedde. 1993. A chicken RAD51 homologue is expressed at high levels in lymphoid and reproductive organs. Nucleic Acids Res. 21:1577-1580.
10. Boulton, S. J., and S. P. Jackson. 1996. Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J. 15:5093-5103.
11. Cavener, D. R. 1987. Comparison of the consensus sequences flanking translational start sites in Drosophila and vertebrates. Nucleic Acids Res. 4:1353-1361.
12. Chepurnaya, O. V., S. A. Kozhin, V. T. Peshekhonov, and V. G. Korolev. 1995. RAD58(XRS4) - a new gene in the RAD52 epistasis group. Curr. Genet. 28:274-279.
13. Contopoulou, C. R., V. E. Cook, and R. K. Mortimer. 1987. Analysis of DNA double strand breakage and repair using orthogonal field alternation gel electrophoresis. Yeast 3:71-76.
14. Dolganov, G. M., R. S. Maser, A. Novikov, L. Tosto, S. Chong, D. A. Bressan, and H. J. Petrini. 1996. Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair. Mol. Cell. Biol. 16:4832-4841.
15. Eckardt-Schupp, E. Personal communication.
16. Eisen, J. A., K. S. Sweder, and P. C. Hanawalt. 1995. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res. 23:2715-2723.
17. Engels, W. R., C. R. Preston, P. Thompson, and W. B. Eggleston. 1986. In situ hybridization to Drosophila salivary chromosomes with biotinylated DNA probes and alkaline phosphatase. Focus 8:6-8.
18. Flygare, J., F. Benson, and D. Hellgren. 1996. Expression of the human RAD51 gene during the cell cycle in primary human peripheral blood lymphocytes. Biochim. Biophys. Acta 1312:231-236.
19. Friedberg, E. C., G. C. Walker, and W. Siede. 1995. DNA repair and mutagenesis. ASM Press, Washington, D.C.
20. Game, J. C. 1993. DNA double-strand breaks and the RAD50-RAD57 genes in Saccharomyces. Semin. Cancer Biol. 4:73-83.
21. Godwin, A. R., R. J. Bollag, D.-M. Christie, and R. M. Liskay. 1994. Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells. Proc. Natl. Acad. Sci. USA 91:12554-12558.
22. Gorbalenya, A. E., and E. V. Koonin. 1993. Helicases: amino acid sequence comparisons and structure-function relationships. Curr. Opin. Struct. Biol. 3:419-429.
23. Haynes, R. H., and B. A. Kunz. 1981. DNA repair and mutagenesis in yeast, p. 371-414. In J. Strathern, E. W. Jones and J. R. Broach (ed.), The molecular biology of the yeast Saccharomyces cerevisiae: life cycle and inheritance. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
24. Jacoby, D. B., and P. C. Wensink. 1994. Yolk protein factor 1 is a Drosophila homolog of Ku, the DNA-binding subunit of a DNA-dependent protein kinase from humans. J. Biol. Chem. 269:11484-11491.
25. +, a Schizosaccharomyces pombe homolog of the Saccharomyces cerevisiae RAD51 gene. Gene 142:207-211.
26. Jeggo, P. A., G. E. Taccioli, and S. P. Jackson. 1995. Menage à trois: double strand break repair, V(D)J recombination and DNA-PK. Bioessays 17:949-957.
27. Jeong-Yu, S., and D. Carroll. 1992. Test of the double-strand break repair model of recombination in Xenopus laevis oocytes. Mol. Cell. Biol. 12:112-119.
28. Kanaar, R., C. Troelstra, S. M. A. Swagemakers, J. Essers, B. Smit, J.-H. Franssen, A. Pastink, O. Bezzubova, J.-M. Buerstedde, B. Clever, W.-D. Heyer, and J. H. J. Hoeijmakers. 1996. Characterization of human and mouse homologs of the Saccharomyces cerevisiae double-strand DNA break repair gene RAD54. Curr. Biol. 6:828-838.
29. Lehman, C. W., J. K. Trautman, and D. Carroll. 1994. Illegitimate recombination in Xenopus: characterization of end-joined junctions. Nucleic Acids Res. 22:434-442.
30. Lim, D.-S., and P. Hasty. 1996. A mutation in mouse rad51 results in an early embryonic lethal that is suppresses by a mutation in p53. Mol. Cell. Biol. 16:7133-7143.
31. Lin, F.-L. M., K. Sperle, and N. Sternberg. 1990. Repair of double-stranded DNA breaks by homologous DNA fragments during transfer of DNA into mouse L cells. Mol. Cell. Biol. 10:113-119.
32. Lindsley, D. L., and G. G. Zimm. 1992. The genome of Drosophila melanogaster. Academic Press, Inc., San Diego, Calif.
33. Lukacsovich, T., D. Yang, and A. S. Waldman. 1994. Repair of a specific double-strand break generated within a mammalian chromosome by yeast endonuclease I-SceI. Nucleic Acids Res. 22:5649-5657.
34. McKee, B. D., X.-J. Ren, and C.-S. Hong. 1996. A recA-like gene in Drosophila melanogaster that is expressed at high levels in female but not male meiotic tissues. Chromosoma 104:479-488.
35. Milne, G. T., S. Jin, K. B. Shannon, and D. T. Weaver. 1996. Mutations in two ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:4189-4198.
36. Morita, T., Y. Yoshimura, A. Yamamoto, K. Murata, M. Mori, H. Yamamoto, and A. Matsushiro. 1993. A mouse homolog of the Escherichia coli recA and Saccharomyces cerevisiae RAD51 genes. Proc. Natl. Acad. Sci. USA 90:6577-6580.
37. Mortensen, U. H., C. Bendixen, I. Sunjevaric, and R. Rothstein. 1996. DNA strand annealing is promoted by the yeast Rad52 protein. Proc. Natl. Acad. Sci. USA 93:10729-10734.
38. Mozer, B., R. Marlor, S. Parkhurst, and V. Corces. 1985. Characterization and developmental expression of a Drosophila ras oncogene. Mol. Cell. Biol. 5:885-889.
39. Muris, D. F. R., O. Bezzubova, J.-M. Buerstedde, K. Vreeken, A. S. Balajee, C. J. Osgood, C. Troelstra, J. H. J. Hoeijmakers, K. Ostermann, H. Schmidt, A. T. Natarajan, J. C. J. Eeken, P. H. M. Lohman, and A. Pastink. 1994. Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination. Mutat. Res. 315:295-305.
40. Muris, D. F. R., K. Vreeken, A. M. Carr, B. C. Broughton, A. R. Lehmann, P. H. M. Lohman, and A. Pastink. 1993. Cloning the RAD51 homologue of Schizosaccharomyces pombe. Nucleic Acids Res. 12:4586-4591.
41. +, a gene involved in the repair of radiation damage and replication fidelity. J. Cell Sci. 109:73-81.
42. Ostermann, K., A. Lorentz, and H. Schmidt. 1993. The fission yeast rad22 gene, having a function in mating-type switching and repair of DNA damages, encodes a protein homolog to Rad52 of Saccharomyces cerevisiae. Nucleic Acids Res. 21:5940-5944.
43. Pastink, A., E. Heemskerk, M. J. M. Nivard, C. J. van Vliet, and E. W. Vogel. 1991. Mutational specificity of ethyl methanesulfonate in excision-repair proficient and deficient strains of Drosophila melanogaster. Mol. Gen. Genet. 229:213-218.
44. Petes, T. D., R. E. Malone, and L. S. Symington. 1991. Recombination in yeast, p. 407-521. In J. Broach, J. Pringle, and E. Jones (ed.), The molecular and cellular biology of the yeast Saccharomyces: genome dynamics, protein synthesis, and energetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
45. Petrini, J. H. J., M. E. Walsh, C. DiMare, X.-N. Chen, J. R. Korenberg, and D. T. Weaver. 1995. Isolation and characterization of the human MRE11 homologue. Genomics 29:80-86.
46. Price, A. 1993. The repair of ionising radiation-induced damage to DNA. Cancer Biol. 4:61-71.
47. Roth, D. B., T. Lindahl, and M. Gellert. 1995. How to make ends meet. Curr. Biol. 5:496-499.
48. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
49. Sander, M., K. Owenhaupt, W. S. Lane, and A. Rich. 1991. Cloning and characterization of Rrp1, the gene encoding Drosophila strand transferase: carboxy-terminal homology to DNA repair endo/exonucleases. Nucleic Acids Res. 19:4523-4529.
50. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-termination inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
51. Shen, Z., K. Denison, R. Lobb, J. M. Gatewood, and D. J. Chen. 1995. The human and mouse homologs of the yeast RAD52 gene: cDNA cloning, sequence analysis, assignment to human chromosome 12p12.2-p13, and mRNA expression in mouse tissues. Genomics 25:199-206.
52. Shinohara, A., H. Ogawa, Y. Matsuda, N. Ushio, K. Ikeo, and T. Ogawa. 1993. Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA. Nat. Genet. 4:239-243.
53. Shinohara, A., H. Ogawa, and T. Ogawa. 1992. RAD51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell 69:457-470.
54. Siede, W., A. A. Friedl, J. Dianova, F. Eckardt-Schupp, and E. C. Friedberg. 1996. The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination. Genetics 142:91-102.
55. Sung, P., and D. L. Robberson. 1995. DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA. Cell 82:453-161.
56. Szakmary, A. Personal communication.
57. Taki, T., T. Ohnishi, A. Yamamote, S. Hiraga, N. Arita, S. Izumoto, T. Hayakawa, and T. Morita. 1996. Antisense inhibition of the RAD51 enhances radiosensitivity. Biochem. Biophys. Res. Commun. 223:434-438.
58. Tashiro, S., N. Kotomura, A. Shinohara, K. Tanaka, K. Ueda, and N. Kamada. 1996. S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes. Oncogene 12:2165-2170.
59. Tavassoli, M., M. Shayeghi, A. Nasim, and F. Z. Watts. 1995. Cloning and characterisation of the Schizosaccharomyces pombe rad32 gene: a gene required for repair of double-strand breaks and recombination. Nucleic Acids Res. 23:383-388.
60. Troelstra, C., A. van Gool, J. de Wit, W. Vermeulen, D. Bootsma, and J. H. J. Hoeijmakcrs. 1992. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell 71:939-953.
61. Tsuzuki, T., Y. Fujii, K. Sakumi, Y. Tominaga, K. Nakao, M. Sekiguchi, A. Matusuhiro, Y. Yoshimura, and T. Morita. 1996. Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc. Natl. Acad. Sci. USA 93:6236-6240.
62. Vogel, E. W. 1992. Tests for recombinagens in somatic cells of Drosophila. Mutat. Res. 284:159-175.
63. Weaver, D. T. 1995. What to do at an end: DNA double-strand-break repair. Trends Genet. 11:388-392.
64. Yamamoto, A., T. Taki, H. Yagi, T. Habu, K. Yoshida, Y. Yoshimura, K. Yamamoto, A. Matsushiro, Y. Nishimune, and T. Morita. 1996. Cell cycle-dependent expression of the mouse Rad51 gene in proliferating cells. Mol. Gen. Genet. 251:1-12.
65. Zdzienicka, M. Z. 1995. Mammalian mutants defective in the response to ionizing radiation-induced DNA damage. Mutat. Res. 336:203-213.