Structures of F420H2:NADP+ oxidoreductase with and without its substrates bound

EMBO Journal

Volumn 20, Issue 23, 2001, Pages 6561-6569

  Warkentin, Eberhard ^a   Mamat, Björn ^a,b   Sordel Klippert, Melanie ^b   Wicke, Michaela ^b   Thauer, Rudolf K ^b   Iwata, Momi ^c   Iwata, So ^c   Ermler, Ulrich ^a   Shima, Seigo ^b  

^a MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Crystal structure; Drug design; F420; Hydride transfer; Oxidoreductase

Indexed keywords

5' DEAZAFLAVIN DERIVATIVE; BACTERIAL ENZYME; COENZYME F420; FLAVOPROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; UNCLASSIFIED DRUG; DEOXYRIBODIPYRIMIDINE PHOTOLYASE; DRUG DERIVATIVE; F420 DEPENDENT NADP REDUCTASE; F420-DEPENDENT NADP REDUCTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; RIBOFLAVIN;

AMINO TERMINAL SEQUENCE; ARCHAEOGLOBUS FULGIDUS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; BINDING SITE; CATALYSIS; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE;

BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; DEOXYRIBODIPYRIMIDINE PHOTO-LYASE; DIMERIZATION; MODELS, CHEMICAL; MODELS, MOLECULAR; NADH, NADPH OXIDOREDUCTASES; NADP; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RIBOFLAVIN; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T;

EID: 0035803592     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.23.6561     Document Type: Article

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