The crystal structure of plant acetohydroxy acid isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65 Å resolution

EMBO Journal

Volumn 16, Issue 12, 1997, Pages 3405-3415

  Biou, Valérie ^b   Dumas, Renaud ^a   Cohen Addad, Claudine ^b   Douce, Roland ^a   Job, Dominique ^a   Pebay Peyroula, Eva ^b  

^a SANOFI   (France)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

Enzyme structure function studies; Herbicide target; Isomeroreductase; Three dimensional structure; Two cation containing active site

Indexed keywords

HERBICIDE; HYDROXYACID; ISOLEUCINE; KETOL ACID REDUCTOISOMERASE; MAGNESIUM ION; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; VALINE; XYLOSE ISOMERASE;

AMINO ACID SEQUENCE; AMINO ACID SYNTHESIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVE SITE; NONHUMAN; PHYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN FOLDING;

ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; CATIONS, DIVALENT; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ENZYME INHIBITORS; HERBICIDES; HYDROXAMIC ACIDS; KETOL-ACID REDUCTOISOMERASE; LIGANDS; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NADP; PLANT PROTEINS; RECOMBINANT FUSION PROTEINS; SPINACIA OLERACEA;

ANIMALIA;

EID: 0030996769     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.12.3405     Document Type: Article

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