Why do asthmatic subjects respond so strongly to inhaled adenosine?

Life Sciences

Volumn 69, Issue 11, 2001, Pages 1225-1240

  Meade, Christopher J ^a   Dumont, Indepencia ^a   Worrall, Liam ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Adenosine; Asthma; Eosinophil; Hyperreactivity

Indexed keywords

ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ADENOSINE A2 RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ADENOSINE RECEPTOR STIMULATING AGENT; ALLERGEN; ANTIASTHMATIC AGENT; ANTIGEN; ASTEMIZOLE; BECLOMETASONE DIPROPIONATE; BUDESONIDE; CROMOGLYCATE DISODIUM; ENPROFYLLINE; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; IMMUNOGLOBULIN E; KETANSERIN; LIPOXYGENASE; N6 2 (4 AMINOPHENYL)ETHYLADENOSINE; NEDOCROMIL; RECEPTOR SUBTYPE; SEROTONIN; SEROTONIN 2A ANTAGONIST; STEROID; TERFENADINE; THEOPHYLLINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHINE DERIVATIVE;

AIRWAY RESISTANCE; ASTHMA; BRONCHOSPASM; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; HISTAMINE RELEASE; HUMAN; IMMUNITY; IMMUNIZATION; INHIBITION KINETICS; LOEFFLER PNEUMONIA; MAST CELL; MEDIATOR RELEASE; NERVE TRACT; NONHUMAN; PATHOPHYSIOLOGY; RAT STRAIN; SEROTONIN RELEASE; SHORT SURVEY; SPECIES DIFFERENCE;

ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ADMINISTRATION, INHALATION; ANIMALS; ASTHMA; BRONCHIAL SPASM; BRONCHOCONSTRICTION; DISEASE MODELS, ANIMAL; EOSINOPHILIA; HUMANS; MAST CELLS; RATS; RATS, INBRED STRAINS; RECEPTORS, PURINERGIC P1; VASODILATOR AGENTS;

ANIMALIA;

EID: 0035800376     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01231-0     Document Type: Review

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