Pharmacological characterization of adenosine A(2B) receptors. Studies in human mast cells co-expressing A(2A) and A(2B) adenosine receptor subtypes

Biochemical Pharmacology

Volumn 55, Issue 5, 1998, Pages 627-633

  Feoktistov, Igor ^a   Biaggioni, Italo ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Adenosine; cAMP; Fura 2; Mast cells; Purinergic; Receptors

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 6 N BENZYLADENOSINE 5' (N ETHYLCARBOXAMIDE); 6 N BENZYLADENOSINE 5' (N METHYLCARBOXAMIDE); ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2B RECEPTOR; ADENOSINE RECEPTOR; ADENYLATE CYCLASE; CYCLIC AMP; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; DOSE RESPONSE; ERYTHROLEUKEMIA CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MAST CELL; PRIORITY JOURNAL;

NON-PROGRAMMATIC;

ADENOSINE; ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); CALCIUM; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MAST CELLS; PHENETHYLAMINES; PYRIMIDINES; RECEPTORS, PURINERGIC P1; TRIAZOLES; TUMOR CELLS, CULTURED;

EID: 0032030579     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00512-1     Document Type: Article

References (34)

1. 1. Daly JW, Butts-Lamb P and Padgett W, Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines. Cell Mol Neurobiol 3: 69-80, 1983.
2. 3H]NECA in rat striatal membranes. Mol Pharmacol 29: 331-346, 1986.
3. 2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest 96: 1979-1986, 1995.
4. 4. Marquardt DL, Walker LL and Heinemann S, Cloning of two adenosine receptor subtypes from mouse bone marrow-derived mast cells. J Immunol 152: 4508-4515, 1994.
5. 5. Boyle DL, Sajjadi FG and Firestein GS, Inhibition of synoviocyte collagenase gene expression by adenosine receptor stimulation. Arthritis Rheum 39: 923-930, 1996.
6. 2b receptors mediate an increase in interleukin (IL)-6 mRNA and IL-6 protein synthesis in human astroglioma cells. J Neurochem 66: 1426-1431, 1996.
7. 2b receptor. Hypertension 27: 786-793, 1996.
8. 2B receptors in the guinea pig aorta. Eur J Pharmacol 216: 235-242, 1992.
9. 2 adenosine receptors in the aorta and the coronary vessels from the guinea pig. J Pharmacol Exp Ther 265: 248-253, 1993.
10. 2-purinoceptors to the control of vascular tone in the rat isolated mesenteric arterial bed. Br J Pharmacol 115: 648-652, 1995.
11. 11. Haynes JJ, Obikao B, Thompson WJ and Downey J, Adenosine-induced vasodilation: Receptor characterization in pulmonary circulation. Am J Physiol 268: H1862-H1868, 1995.
12. 6-cyclopentyladenosine. J Pharmacol Exp Ther 270: 893-899, 1994.
13. 13. Chiang PH, Wu SN, Tsai EM, Wu CC, Shen MR and Huang CH, Adenosine modulation of neurotransmission in penile erection. Br J Clin Pharmacol 38: 357-362, 1994.
14. 2 receptor-cAMP system in human aortic endothelial cells. Biochem Biophys Res Commun 199: 905-910, 1994.
15. 2b receptors coupled to distinct interactive signaling pathways in intestinal muscle cells. J Pharmacol Exp Ther 274: 300-306, 1995.
16. 2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia. J Biol Chem 270: 2387-2394, 1995.
17. 17. Hancock DL and Coupar IM, Functional characterization of the adenosine receptor mediating inhibition of intestinal secretion. Br J Pharmacol 114: 152-156, 1995.
18. 2b receptors in the rat pineal gland. Eur J Pharmacol 225: 359-360, 1992.
19. 2+ influx and activates a protein phosphatase in bovine adrenal chromaffin cells. J Neurochem 64: 77-84, 1995.
20. 2 receptors modulate extracellular dopamine levels in rat striatum. Neurosci Lett 212: 53-56, 1996.
21. 2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: Characterization with radioligand binding and by activation of adenylate cyclase. Mol Pharmacol 41: 352-359, 1992.
22. 2a adenosine receptor-mediated cAMP elevation in rat pheochromocytoma PC12 cells. Mol Pharmacol 44: 950-958, 1993.
23. 2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists. Naunyn Schmiedebergs Arch Pharmacol 353: 250-260, 1996.
24. 2A receptors mediate the inhibitory effect of adenosine on formyl-Met-Leu-Phe-stimulated respiratory burst in neutrophil leucocytes. Naunyn Schmiedebergs Arch Pharmacol 354: 262-267, 1996.
25. 2 receptor subtypes. Mol Pharmacol 43: 909-914, 1993.
26. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
27. 3-selective adenosine agonists. J Med Chem 37: 636-646, 1994.
28. 2a adenosine receptor antagonist. J Pharmacol Exp Ther 276: 398-404, 1996.
29. 3H]SCH58261 to coronary artery membranes. Circ Res 79: 1153-1160, 1996.
30. 3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells. J Biol Chem 268: 16887-16890, 1993.
31. 3 adenosine receptor. Mol Pharmacol 45: 1101-1111, 1994.
32. 2 receptor agonist CGS 21680 on in vitro electrophysiology, cAMP formation and dopamine release in rat hippocampus and striatum. J Pharmacol Exp Ther 252: 1134-1141, 1990.
33. 2b adenosine receptor in NIH 3T3 fibroblasts. Biochem Pharmacol 47: 801-814, 1994.
34. 34. Kenakin T, Pharmacologic Analysis of Drug-Receptor Interaction, 2nd Edn. Raven Press, New York, 1993.